{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T12:37:24Z","timestamp":1784810244903,"version":"3.55.0"},"reference-count":20,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T00:00:00Z","timestamp":1724025600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Addis Ababa University","award":["GSR\/094"],"award-info":[{"award-number":["GSR\/094"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCDD"],"abstract":"<jats:p>Background: Congenital heart disease (CHD) encompasses morphofunctional anomalies in the heart and circulatory system present at birth, which may not become apparent until later in life. In Ethiopia, there needs to be more understanding of the prevalence, patterns, and associated complications of CHD malformations. This study aimed to investigate the patterns and complications of CHDs among patients receiving follow-up care at a specialized university referral hospital in Ethiopia. Methods: A hospital-based cross-sectional study was conducted on 199 patients with CHDs to assess the patterns and complications of defects. Retrospective data were collected from 16,972 patients who had follow-ups at a cardiac clinic in 2021 using medical records, and a statistical analysis was performed with SPSS version 24. Results: The most prevalent types of CHDs in our study population were atrial septal defects (ASDs) at 41.2% (82 cases), ventricular septal defects (VSDs) at 26.6% (53 cases), and patent ductus arteriosus (PDAs) at 9.5% (19 cases). Complications related to CHDs were observed in 69.3% (138) of patients, with 30.7% (61) experiencing a single complication and 39.2% (87) experiencing multiple complications. Conclusion: This study found a higher prevalence of CHDs in females (77.8%) compared to males, a trend consistent across various atrial and ventricular defect types. Individuals aged 15 to 25 years exhibited the highest incidence of ASD and VSD. Moreover, CHD-related anomalies were present in 69.3% of the patients studied.<\/jats:p>","DOI":"10.3390\/jcdd11080253","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T05:19:36Z","timestamp":1724044776000},"page":"253","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Patterns and Complications of Congenital Heart Disease in Adolescents and Adults in Ethiopia"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4177-3554","authenticated-orcid":false,"given":"Misikr Alemu","family":"Eshetu","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, School of Medicine, College of Medicine and Health Science, Mizan-Tepi University, Mizan-Aman P.O. Box 260, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dejuma Yadeta","family":"Goshu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, College of Health Sciences, Addis Ababa University, Addis Ababa P.O. Box 9086, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6665-7900","authenticated-orcid":false,"given":"Molla Asnake","family":"Kebede","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, School of Medicine, College of Medicine and Health Science, Mizan-Tepi University, Mizan-Aman P.O. Box 260, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9603-0029","authenticated-orcid":false,"given":"Hashim Meketa","family":"Negate","sequence":"additional","affiliation":[{"name":"Department of Radiology, School of Medicine, College of Medicine and Health Science, Mizan-Tepi University, Mizan-Aman P.O. Box 260, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3571-9472","authenticated-orcid":false,"given":"Abiel Berhe","family":"Habtezghi","sequence":"additional","affiliation":[{"name":"Mercy Catholic Medical Center, Darby, PA 19023, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula Marsh","family":"Gregory","sequence":"additional","affiliation":[{"name":"Meritus Medical Center, Meritus School of Osteopathic Medicine, Hagerstown, MD 21742, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8220-0473","authenticated-orcid":false,"given":"Amenu Tolera","family":"Wirtu","sequence":"additional","affiliation":[{"name":"Meritus Medical Center, Meritus School of Osteopathic Medicine, Hagerstown, MD 21742, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0566-0417","authenticated-orcid":false,"given":"Jickssa Mulissa","family":"Gemechu","sequence":"additional","affiliation":[{"name":"Department of Foundational Medical Studies, Oakland University William Beaumont School of Medicine, Rochester, MI 48309, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,19]]},"reference":[{"key":"ref_1","unstructured":"Douglas, L., Douglas, P.Z., Peter, L., and Robert, O. 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