{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:40:31Z","timestamp":1760031631289,"version":"build-2065373602"},"reference-count":22,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T00:00:00Z","timestamp":1743552000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Open Acess Publishing Fund of the Philipps-Universit\u00e4t Marburg"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCDD"],"abstract":"<jats:p>(1) Background: The measurement of hemodynamic parameters has proven to be crucial in the treatment of hospitalized heart failure patients, necessitating invasive measurement by right heart catheterization (RHC). The reliability of whole-body impedance cardiography (ICG) among this cohort has not been investigated to date; (2) Methods: The RHC and whole-body ICG examinations measured cardiac output (CO), the cardiac index (CI), total peripheral resistance (TPR), and pulmonary vascular resistance (PVR). To assess the accuracy of the whole-body ICG measurement, bias and precision were calculated as the mean difference and the twofold standard deviation between the average values of measurements; (3) Results: A total of 203 patients were analyzed. No significant bias was observed between the non-invasive CO and CI measurements when compared with the RHC measurements (\u22120.14 \u00b1 2.56 L\/min, p = 0.1; \u22120.09 \u00b1 1.3 L\/min\/m2, p = 0.06), but a significant bias occurred in the measurement of non-invasive TPR and non-invasive PVR (\u22121243 \u00b1 3510 dyn \u00d7 s\u22121 \u00d7 cm\u22125, p = 0.001; \u2212121 \u00b1 504 dyn \u00d7 s\u22121 \u00d7 cm\u22125, p &lt; 0.001); (4) Conclusions: CO and CI can be measured with whole-body ICG among hospitalized CHF patients with acceptable accuracy. The reliability of measuring TPR and PVR should be further investigated.<\/jats:p>","DOI":"10.3390\/jcdd12040128","type":"journal-article","created":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T04:06:05Z","timestamp":1743566765000},"page":"128","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Non-Invasive Measurement of Hemodynamic Parameters via Whole-Body Impedance Cardiography Among Hospitalized Heart Failure Patients: An Effective Alternative to Invasive Right Heart Catheterization?"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0526-7989","authenticated-orcid":false,"given":"Felix","family":"Ausbuettel","sequence":"first","affiliation":[{"name":"Department of Cardiology, University Hospital Marburg, Baldingerstra\u00dfe, 35043 Marburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabah","family":"Khwamurad","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiovascular Center Bad Neustadt\/Saale, Von-Guttenberg-Stra\u00dfe 11, 97616 Bad Neustadt\/Saale, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murad Haj","family":"Abdo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiovascular Center Bad Neustadt\/Saale, Von-Guttenberg-Stra\u00dfe 11, 97616 Bad Neustadt\/Saale, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5256-3823","authenticated-orcid":false,"given":"Sebastian","family":"Kerber","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiovascular Center Bad Neustadt\/Saale, Von-Guttenberg-Stra\u00dfe 11, 97616 Bad Neustadt\/Saale, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3590-5980","authenticated-orcid":false,"given":"Karin","family":"Nentwich","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiovascular Center Bad Neustadt\/Saale, Von-Guttenberg-Stra\u00dfe 11, 97616 Bad Neustadt\/Saale, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Hautmann","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiovascular Center Bad Neustadt\/Saale, Von-Guttenberg-Stra\u00dfe 11, 97616 Bad Neustadt\/Saale, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9549-3503","authenticated-orcid":false,"given":"Sebastian","family":"Barth","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiovascular Center Bad Neustadt\/Saale, Von-Guttenberg-Stra\u00dfe 11, 97616 Bad Neustadt\/Saale, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1161\/CIRCRESAHA.113.300268","article-title":"Epidemiology of heart failure","volume":"113","author":"Roger","year":"2013","journal-title":"Circ. Res."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1002\/ejhf.1594","article-title":"Survival of patients with chronic heart failure in the community: A systematic review and meta-analysis","volume":"21","author":"Jones","year":"2019","journal-title":"Eur. J. Heart Fail."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur. Heart J."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.jacc.2004.03.060","article-title":"Cardiac power is the strongest hemodynamic correlate of mortality in cardiogenic shock: A report from the SHOCK trial registry","volume":"44","author":"Fincke","year":"2004","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1253\/circj.70.1164","article-title":"Impedance cardiography for cardiac output estimation: Reliability of wrist-to-ankle electrode configuration","volume":"70","author":"Paredes","year":"2006","journal-title":"Circ. J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1378\/chest.125.4.1431","article-title":"Accurate, noninvasive continuous monitoring of cardiac output by whole-body electrical bioimpedance","volume":"125","author":"Cotter","year":"2004","journal-title":"Chest"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1097\/00003246-199705000-00012","article-title":"Whole-body impedance cardiography in the measurement of cardiac output","volume":"25","author":"Kaukinen","year":"1997","journal-title":"Crit. Care Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1097\/00003246-199910000-00023","article-title":"Cardiac output can be reliably measured noninvasively after coronary artery bypass grafting operation","volume":"27","author":"Kaukinen","year":"1999","journal-title":"Crit. Care Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"335","DOI":"10.4103\/aca.aca_44_21","article-title":"Comparative study of cardiac output measurement by regional impedance cardiography and thermodilution method in patients undergoing off pump coronary artery bypass graft surgery","volume":"25","author":"Guha","year":"2022","journal-title":"Ann. Card. Anaesth."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1053\/jcan.2003.47","article-title":"Cardiac output measurement after coronary artery bypass grafting using bolus thermodilution, continuous thermodilution, and whole-body impedance cardiography","volume":"17","author":"Kaukinen","year":"2003","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1097\/CRD.0000000000000223","article-title":"Thermodilution Cardiac Output: A Concept Over 250 Years in the Making","volume":"27","author":"Argueta","year":"2019","journal-title":"Cardiol. Rev."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Kubiak, G.M., Ciarka, A., Biniecka, M., and Ceranowicz, P. (2019). Right Heart Catheterization-Background, Physiological Basics, and Clinical Implications. J. Clin. Med., 8.","DOI":"10.3390\/jcm8091331"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Tamimi, O., and Mohammed, M.H.A. (2021). Pulmonary Vascular Resistance Measurement Remains Keystone in Congenital Heart Disease Management. Front. Cardiovasc. Med., 8.","DOI":"10.3389\/fcvm.2021.607104"},{"key":"ref_14","first-page":"216","article-title":"Resistance reconstructed estimation of total peripheral resistance from computa-tionally derived cardiac output","volume":"49","author":"Hill","year":"2013","journal-title":"Biomed. Sci. Instrum."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1378\/chest.126.4.1313","article-title":"New formula for pre-dicting mean pulmonary artery pressure using systolic pulmonary artery pressure","volume":"126","author":"Chemla","year":"2004","journal-title":"Chest"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1002\/ejhf.813","article-title":"Epidemiology and one-year outcomes in patients with chronic heart failure and preserved, mid-range and reduced ejection fraction: An analysis of the ESC Heart Failure Long-Term Registry","volume":"19","author":"Chioncel","year":"2017","journal-title":"Eur. J. Heart Fail."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ahj.2020.06.002","article-title":"A multinational registry to study the characteristics and outcomes of heart failure patients: The global congestive heart failure (G-CHF) registry","volume":"227","author":"Joseph","year":"2020","journal-title":"Am. Heart J."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2812","DOI":"10.1097\/00003246-200008000-00022","article-title":"Noninvasive whole-body electrical bioimpedance cardiac output and invasive thermodilution cardiac output in high-risk surgical patients","volume":"28","author":"Imhoff","year":"2000","journal-title":"Crit. Care Med."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1007\/s001340050469","article-title":"Non-invasive measurement of cardiac output: Whole-body impedance cardiography in simultaneous comparison with thermodilution and direct oxygen Fick methods","volume":"23","author":"Kaukinen","year":"1997","journal-title":"Intensive Care Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"189","DOI":"10.4103\/aca.ACA_1_19","article-title":"Com-parison of continuous cardiac output monitoring derived from regional impedance cardiography with continuous ther-modilution technique in cardiac surgical patients","volume":"23","author":"Bhavya","year":"2020","journal-title":"Ann. Card. Anaesth."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1253\/circj.CJ-13-0172","article-title":"Noninvasive and simple assessment of cardiac output and pulmonary vascular resistance with whole-body impedance cardiography is useful for monitoring patients with pulmonary hypertension","volume":"77","author":"Taniguchi","year":"2013","journal-title":"Circ. J."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"154281","DOI":"10.1016\/j.jcrc.2023.154281","article-title":"Echocardiographic assessment of pulmonary capillary wedge pressure by E\/e\u2019 ratio: A systematic review and meta-analysis","volume":"76","author":"Martelli","year":"2023","journal-title":"J. Crit. 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