{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:16:40Z","timestamp":1789672600076,"version":"4.0.1"},"reference-count":50,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Institute on Aging","award":["P30AG072959"],"award-info":[{"award-number":["P30AG072959"]}]},{"name":"National Institute on Aging","award":["P30AG017266"],"award-info":[{"award-number":["P30AG017266"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCDD"],"abstract":"<jats:p>Hypertension is a major public health concern, especially in older adults, and gender differences are a factor in terms of its prevalence. Social connections benefit health, while social isolation is linked to negative outcomes. Prior studies suggest social isolation and connectedness vary by gender, but few have explored this relationship with hypertension. This study examined gender differences in the association between social isolation and hypertension in older adults using data from the National Survey of American Life (1280 adults aged \u226555). Weighted logistic regressions tested gender differences in objective and subjective social isolation and hypertension. Both men and women who were objectively isolated from family and friends, or only friends, were less likely to have hypertension than those not isolated. However, when accounting for subjective isolation, only isolation from family predicted hypertension. Gender moderated this relationship\u2014men isolated from family and friends had a higher likelihood of hypertension, while no such association was found for women. Findings suggest that preventing objective isolation, particularly from family, may help reduce hypertension risk in older adults. This study highlights the need to further investigate social isolation\u2019s impact on health and its underlying mechanisms among older adults in the U.S.<\/jats:p>","DOI":"10.3390\/jcdd12040136","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T03:36:45Z","timestamp":1743737805000},"page":"136","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Gender Differences in Objective and Subjective Social Isolation and Self-Reported Hypertension in Older Adults"],"prefix":"10.3390","volume":"12","author":[{"given":"Tyrone C.","family":"Hamler","sequence":"first","affiliation":[{"name":"Graduate School of Social Work, University of Denver, Denver, CO 80210, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2592-0773","authenticated-orcid":false,"given":"Ann W.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Jack, Joseph and Morton Mandel School of Applied Social Sciences, Case Western Reserve University, Cleveland, OH 44106, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry Owen","family":"Taylor","sequence":"additional","affiliation":[{"name":"Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, ON M5S 1V4, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weidi","family":"Qin","sequence":"additional","affiliation":[{"name":"Sandra Rosenbaum School of Social Work, University of Wisconsin-Madison, Madison, WI 53706, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0860-6317","authenticated-orcid":false,"given":"Fei","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Social Work, University of Tennessee-Knoxville, Knoxville, TN 37210, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,4]]},"reference":[{"key":"ref_1","unstructured":"Centers for Disease Control and Prevention (2025, March 15). 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