{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:30:40Z","timestamp":1760236240676,"version":"build-2065373602"},"reference-count":26,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T00:00:00Z","timestamp":1636588800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCDD"],"abstract":"<jats:p>Percutaneous coronary intervention (PCI) of bifurcation lesions is a technical challenge associated with high risk of adverse events, especially in primary PCI. The aim of the study is to analyze long-term outcomes after PCI for coronary bifurcation in acute myocardial infarction (AMI). The outcome was defined as the rate of major adverse cardiac event related to target lesion failure (MACE-TLF) (death-TLF, nonfatal myocardial infarction-TLF and target lesion revascularization (TLR)) and the rate of stent thrombosis (ST). From 306 patients enrolled to the registry, 113 were diagnosed with AMI. In the long term, AMI was not a risk factor for MACE-TLF. The risk of MACE-TLF was dependent on the culprit lesion, especially in the right coronary artery (RCA) and side branch (SB) with a diameter &gt;3 mm. When PCI was performed in the SB, the inflation pressure in SB remained the single risk factor of poor prognosis. The rate of cumulative ST driven by late ST in AMI was dependent on the inflation pressure in the main branch (MB). In conclusion, PCI of bifurcation culprit lesions should be performed carefully in case of RCA and large SB diameter and attention should be paid to high inflation pressure in the SB. On the contrary, the lower the inflation pressure in the MB, the higher the risk of ST.<\/jats:p>","DOI":"10.3390\/jcdd8110155","type":"journal-article","created":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T23:02:41Z","timestamp":1636671761000},"page":"155","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Real-Life Outcomes of Coronary Bifurcation Stenting in Acute Myocardial Infarction (Zabrze\u2013Opole Registry)"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6366-9073","authenticated-orcid":false,"given":"Wojciech","family":"Milejski","sequence":"first","affiliation":[{"name":"2nd Department of Cardiology, Faculty of Medicine in Zabrze, Medical University of Silesia in Katowice, M. Sk\u0142odowskiej-Curie 10, 41-800 Zabrze, Poland"},{"name":"Department of Cardiology, University Hospital in Opole, W. Witosa 26, 45-401 Opole, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerzy","family":"Sacha","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital in Opole, W. Witosa 26, 45-401 Opole, Poland"},{"name":"Faculty of Physical Education and Physiotherapy, Opole University of Technology, Pr\u00f3szkowska 76, 45-758 Opole, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Feusette","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital, Institute of Medical Sciences, University of Opole, W. Witosa 26, 45-401 Opole, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Cisowski","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Hospital, Institute of Medical Sciences, University of Opole, W. Witosa 26, 45-401 Opole, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Muzyk","sequence":"additional","affiliation":[{"name":"2nd Department of Cardiology, Faculty of Medicine in Zabrze, Medical University of Silesia in Katowice, M. Sk\u0142odowskiej-Curie 10, 41-800 Zabrze, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9312-762X","authenticated-orcid":false,"given":"Andrzej","family":"Tomasik","sequence":"additional","affiliation":[{"name":"2nd Department of Cardiology, Faculty of Medicine in Zabrze, Medical University of Silesia in Katowice, M. Sk\u0142odowskiej-Curie 10, 41-800 Zabrze, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5639-2128","authenticated-orcid":false,"given":"Marek","family":"Gierlotka","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital, Institute of Medical Sciences, University of Opole, W. Witosa 26, 45-401 Opole, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0187-1364","authenticated-orcid":false,"given":"Beata","family":"Morawiec","sequence":"additional","affiliation":[{"name":"2nd Department of Cardiology, Faculty of Medicine in Zabrze, Medical University of Silesia in Katowice, M. Sk\u0142odowskiej-Curie 10, 41-800 Zabrze, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4445-9721","authenticated-orcid":false,"given":"Damian","family":"Kawecki","sequence":"additional","affiliation":[{"name":"2nd Department of Cardiology, Faculty of Medicine in Zabrze, Medical University of Silesia in Katowice, M. Sk\u0142odowskiej-Curie 10, 41-800 Zabrze, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,11,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1056\/NEJMoa067731","article-title":"Stent thrombosis in randomized clinical trials of drug-eluting stents","volume":"356","author":"Mauri","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1016\/j.jacc.2012.08.001","article-title":"Third universal definition of myocardial infarction","volume":"60","author":"Thygesen","year":"2012","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1093\/eurheartj\/ehs215","article-title":"ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation","volume":"33","author":"Steg","year":"2012","journal-title":"Eur. Heart J."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2999","DOI":"10.1093\/eurheartj\/ehr236","article-title":"ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC)","volume":"32","author":"Hamm","year":"2011","journal-title":"Eur. Heart J."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1157\/13084649","article-title":"A new classification of coronary bifurcation lesions","volume":"59","author":"Medina","year":"2006","journal-title":"Rev. Espa\u00f1ola Cardiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1161\/CIRCULATIONAHA.106.685313","article-title":"Clinical end points in coronary stent trials: A case for standardized definitions","volume":"115","author":"Cutlip","year":"2007","journal-title":"Circulation"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4244\/EIJV4I1A16","article-title":"Impact of bifurcation lesions on clinical outcome and prognosis of primary angioplasty in acute myocardial infarction","volume":"4","author":"Garot","year":"2008","journal-title":"EuroIntervention"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"817","DOI":"10.4244\/EIJV9I7A135","article-title":"Impact of bifurcation target lesion on angiographic, electrocardiographic, and clinical outcomes of patients undergoing primary percutaneous coronary intervention (from the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction [HORIZONS-AMI] trial)","volume":"9","author":"Dudek","year":"2013","journal-title":"EuroIntervention"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"388","DOI":"10.3346\/jkms.2013.28.3.388","article-title":"Trans-radial versus trans-femoral intervention for the treatment of coronary bifurcations: Results from coronary bifurcation stenting registry","volume":"28","author":"Chung","year":"2013","journal-title":"J. Korean Med. Sci."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Dola, J., Morawiec, B., Wa\u0144ha, W., Nowalany-Kozielska, E., Wojakowski, W., and Kawecki, D. (2020). Results of PCI with drug-eluting stents in an all-comer population depending on vessel diameter. J. Clin. Med., 9.","DOI":"10.3390\/jcm9020524"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e000852","DOI":"10.1136\/openhrt-2018-000852","article-title":"Culprit vessel: Impact on short-term and long-term prognosis in patients with ST-elevation myocardial infarction","volume":"5","author":"Entezarjou","year":"2018","journal-title":"Open Heart"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.jcin.2011.02.016","article-title":"Percutaneous coronary intervention of unprotected left main coronary artery disease as culprit lesion in patients with acute myocardial infarction","volume":"4","author":"Pappalardo","year":"2011","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1016\/j.jcin.2016.06.056","article-title":"Contemporary approach to coronary bifurcation lesion treatment","volume":"9","author":"Sawaya","year":"2016","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.ijcard.2015.03.183","article-title":"Coronary bifurcation lesions: Present status and future perspectives","volume":"187","author":"Leesar","year":"2015","journal-title":"Int. J. Cardiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/s13239-019-00403-8","article-title":"The impact of the right coronary artery geometric parameters on hemodynamic performance","volume":"10","author":"Pinho","year":"2019","journal-title":"Cardiovasc. Eng. Technol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/j.jcin.2014.04.026","article-title":"Impact of the complexity of bifurcation lesions treated with drug-eluting stents: The DEFINITION study (Definitions and impact of complEx biFurcation lesIons on clinical outcomes after percutaNeous coronary IntervenTIOn using drug-eluting steNts)","volume":"7","author":"Chen","year":"2014","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"90","DOI":"10.4244\/EIJ-D-19-00144","article-title":"Percutaneous coronary intervention for obstructive bifurcation lesions: The 14th consensus document from the European Bifurcation Club","volume":"15","author":"Banning","year":"2019","journal-title":"EuroIntervention"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.recesp.2017.12.019","article-title":"Treatment strategy for STEMI with bifurcation culprit lesion undergoing primary PCI: The COBIS II registry","volume":"71","author":"Choi","year":"2018","journal-title":"Rev. Espa\u00f1ola Cardiol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1002\/ccd.27551","article-title":"Comparison of the planned one- and elective two-stent techniques in patients with coronary bifurcation lesions with or without acute coronary syndrome from the COBIS II registry","volume":"92","author":"Kim","year":"2018","journal-title":"Catheter. Cardiovasc. Interv."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Qu, W.-B., Zhang, W., Liu, J.-Y., Zhang, F., Mu, S.-N., Zhang, S.-M., Tang, H., Liu, X.-Q., Li, X.-Q., and Liu, B.-C. (2019). Modified balloon-stent kissing technique avoid side-branch compromise for simple true bifurcation lesions. BMC Cardiovasc. Disord., 19.","DOI":"10.1186\/s12872-019-1052-0"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1016\/j.jacc.2014.02.607","article-title":"Causes of early stent thrombosis in patients presenting with acute coronary syndrome: An ex vivo human autopsy study","volume":"63","author":"Nakano","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_22","first-page":"373","article-title":"First- versus second-generation drug-eluting stents in acute coronary syndromes (Katowice-Zabrze registry)","volume":"106","author":"Kawecki","year":"2016","journal-title":"Arq. Bras. Cardiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/S0140-6736(07)60314-6","article-title":"Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: Data from a large two-institutional cohort study","volume":"369","author":"Daemen","year":"2007","journal-title":"Lancet"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1016\/j.jacc.2006.10.026","article-title":"Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: An observational study of drug-eluting versus bare-metal stents","volume":"48","author":"Pfisterer","year":"2006","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"393","DOI":"10.2147\/VHRM.S23388","article-title":"Everolimus-eluting stents in interventional cardiology","volume":"8","author":"Steinberg","year":"2012","journal-title":"Vasc. Health Risk Manag."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Hafiane, A. (2019). Vulnerable plaque, characteristics, detection, and potential therapies. J. Cardiovasc. Dev. Dis., 6.","DOI":"10.3390\/jcdd6030026"}],"container-title":["Journal of Cardiovascular Development and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2308-3425\/8\/11\/155\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:28:52Z","timestamp":1760167732000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2308-3425\/8\/11\/155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,11]]},"references-count":26,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2021,11]]}},"alternative-id":["jcdd8110155"],"URL":"https:\/\/doi.org\/10.3390\/jcdd8110155","relation":{},"ISSN":["2308-3425"],"issn-type":[{"type":"electronic","value":"2308-3425"}],"subject":[],"published":{"date-parts":[[2021,11,11]]}}}