{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:37:32Z","timestamp":1760236652196,"version":"build-2065373602"},"reference-count":24,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T00:00:00Z","timestamp":1639353600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"MicroPort (China)","award":["none"],"award-info":[{"award-number":["none"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCDD"],"abstract":"<jats:p>Laser balloon (LB) has emerged as an interesting strategy for pulmonary vein isolation in paroxysmal atrial fibrillation (AF). A third-generation LB has recently been developed, allowing a continuous ablation set. We aimed to compare the results from our center\u2019s experience with second and third-generation LBs to a cohort of matched patients who had undergone radiofrequency ablation (RFA) with contact-force catheters. This retrospective monocenter case-control study included our first 50 LB paroxysmal AF ablations (26 second and 24 third-generation LB) and 50 RFA controls, matched on age, sex and left atrial dilation. The two groups had similar baseline parameters. LB procedures were significantly shorter than RFA (129 (110\u2013160) vs. 160 (119\u2013198) min, p = 0.007). During AF ablation, two major complications occurred in each group. At the one-year follow-up, AF recurrence was diagnosed in 7 (14%) of the LB group vs. 14 (28%) of the RFA group (p = 0.14). Moreover, we observed that third-generation LB procedures were associated with shorter laser applications (22 (19\u201329) vs. 69 (55\u201376) min, p &lt; 0.001) and procedural durations (111 (100\u2013128) vs. 151.5 (128.5\u2013167) min, p &lt; 0.001) compared to second-generation LB procedures. In the context of the major increase in the number of AF ablations, LB demonstrated consistent results in terms of clinical success, complications and also reduced procedure durations compared to RFA.<\/jats:p>","DOI":"10.3390\/jcdd8120183","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T01:20:41Z","timestamp":1639444841000},"page":"183","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy and Safety of Second and Third-Generation Laser Balloon for Paroxysmal Atrial Fibrillation Ablation Compared to Radiofrequency Ablation: A Matched-Cohort"],"prefix":"10.3390","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3554-7714","authenticated-orcid":false,"given":"Charles","family":"Guenancia","sequence":"first","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"},{"name":"INSERM-IADI, U1254, 54500 Vand\u0153uvre l\u00e8s-Nancy, France"},{"name":"D\u00e9partement de Cardiologie, CHU de Dijon, 21000 Dijon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2520-3264","authenticated-orcid":false,"given":"Nefissa","family":"Hammache","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"},{"name":"INSERM-IADI, U1254, 54500 Vand\u0153uvre l\u00e8s-Nancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9mence","family":"Docq","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karim","family":"Benali","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"},{"name":"INSERM-IADI, U1254, 54500 Vand\u0153uvre l\u00e8s-Nancy, France"},{"name":"D\u00e9partement de Cardiologie, CHU de Saint-Etienne, 42270 Saint-Priest-en-Jarez, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darren","family":"Hooks","sequence":"additional","affiliation":[{"name":"Cardiology Department, Wellington Hospital, Wellington 6021, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathieu","family":"Echivard","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Pace","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Magnin-Poull","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9025-6821","authenticated-orcid":false,"given":"Christian","family":"de Chillou","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"},{"name":"INSERM-IADI, U1254, 54500 Vand\u0153uvre l\u00e8s-Nancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1080-7425","authenticated-orcid":false,"given":"Jean-Marc","family":"Sellal","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"},{"name":"INSERM-IADI, U1254, 54500 Vand\u0153uvre l\u00e8s-Nancy, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/eurheartj\/ehaa612","article-title":"2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"42","author":"Hindricks","year":"2021","journal-title":"Eur. 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