{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T14:30:32Z","timestamp":1776868232622,"version":"3.51.2"},"reference-count":80,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T00:00:00Z","timestamp":1663286400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCDD"],"abstract":"<jats:p>The global evolution of the SARS-CoV-2 virus is known to all. The diagnosis of SARS-CoV-2 pneumonia is expected to worsen, and mortality will be higher when combined with myocardial injury (MI). The combination of novel coronavirus infections in patients with MI can cause confusion in diagnosis and assessment, with each condition exacerbating the other, and increasing the complexity and difficulty of treatment. It would be a formidable challenge for clinical practice to deal with this situation. Therefore, this review aims to gather literature on the progress in managing MI related to SARS-CoV-2 pneumonia. This article reviews the definition, pathogenesis, clinical evaluation, management, and treatment plan for MI related to SARS-CoV-2 pneumonia based on the most recent literature, diagnosis, and treatment trial reports. Many studies have shown that early diagnosis and implementation of targeted treatment measures according to the different stages of disease can reduce the mortality rate among patients with MI related to SARS-CoV-2 pneumonia. The reviewed studies show that multiple strategies have been adopted for the management of MI related to COVID-19. Clinicians should closely monitor SARS-CoV-2 pneumonia patients with MI, as their condition can rapidly deteriorate and progress to heart failure, acute myocardial infarction, and\/or cardiogenic shock. In addition, appropriate measures need to be implemented in the diagnosis and treatment to provide reasonable care to the patient.<\/jats:p>","DOI":"10.3390\/jcdd9090307","type":"journal-article","created":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T02:06:50Z","timestamp":1663553210000},"page":"307","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The Management of Myocardial Injury Related to SARS-CoV-2 Pneumonia"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5673-3965","authenticated-orcid":false,"given":"Mohammed","family":"Al-Kaif","sequence":"first","affiliation":[{"name":"School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor 11800, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0125-2683","authenticated-orcid":false,"given":"Ahmad","family":"Bitar","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, Michel Sayegh College of Pharmacy, Aqaba University of Technology, South of Aqaba, South Beach Road, Opposite Aqaba Development Corporation Stores, Aqaba 910122, Jordan"},{"name":"Department of Pharmaceutical Technology, Faculty of Pharmacy, Malaysian Allied Health Sciences Academy, Jalan SP 2, Bandar Saujana Putra, Jenjarom 42610, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laith","family":"Al-Kaif","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Techniques, Al Mustaqbal University College, Hillah 51001, Babylon, Iraq"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4336-9468","authenticated-orcid":false,"given":"Nur","family":"Daud","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor 11800, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5491-9851","authenticated-orcid":false,"given":"Abubakar","family":"Sha\u2019aban","sequence":"additional","affiliation":[{"name":"School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4YS, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dzul","family":"Noor","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor 11800, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatimatuzzahra\u2019","family":"Abd Aziz","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor 11800, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4435-1235","authenticated-orcid":false,"given":"Arturo","family":"Cesaro","sequence":"additional","affiliation":[{"name":"Department of Translational Medical Sciences, University of Campania \u201cLuigi Vanvitelli\u201d, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhamad","family":"SK Abdul Kader","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Penang General Hospital, George Town 10990, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Abdul Wahab","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Penang General Hospital, George Town 10990, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chee","family":"Khaw","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Penang General Hospital, George Town 10990, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baharudin","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, University of Malaya, Kuala Lumpur 50603, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet"},{"key":"ref_2","unstructured":"W.H.O. 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