{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T11:18:42Z","timestamp":1790767122552,"version":"4.1.0"},"reference-count":29,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,9,25]],"date-time":"2022-09-25T00:00:00Z","timestamp":1664064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCDD"],"abstract":"<jats:p>This study aims at examining the chronological development of hospitalized cardiovascular and COVID-19 patients and comparing the effects on related sub-disciplines and main diagnoses for pre-pandemic (2017\u20132019) and pandemic (2020\u20132021) years in the setting of a German university maximum care provider. Data were retrospectively retrieved from the hospital performance controlling system for patient collectives with main diagnosis of diseases of the circulatory system (nCirculatory) and COVID-19 secondary diagnosis (nCOVID-19). The cardiovascular patient collective (nCirculatory = 25,157) depicts a steady state in terms of relative yearly development of patient numbers (+0.4%, 2019\u20132020, +0.1%, 2020\u20132021). Chronological assessment points towards monthly decline during lockdowns and phases of high regional incidence of COVID-19 (i.e., 2019\u20132020: March \u221210.2%, April \u221212.4%, December \u221214.8%). Main diagnoses of congestive heart failure (+16.1% 2019\/2020; +19.2% 2019\/2021) and acute myocardial infarction show an increase in case numbers over the course of the whole pandemic (+15.4% 2019\/2020; +9.4% 2019\/2021). The results confirm negative effects on the cardiovascular care situation during the entire pandemic in the setting of a university maximum care provider. A general increase in cardiac disorders and a worrisome turn in case development of acute myocardial infarction emphasize the feared cardiovascular burden of COVID-19.<\/jats:p>","DOI":"10.3390\/jcdd9100325","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T01:41:58Z","timestamp":1664156518000},"page":"325","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Chronological Development of Cardiovascular Disease in Times of COVID-19: A Retrospective Analysis of Hospitalized Diseases of the Circulatory System and COVID-19 Patients of a German University Hospital"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5355-8903","authenticated-orcid":false,"given":"Sebastian","family":"Griewing","sequence":"first","affiliation":[{"name":"University Hospital Marburg, Philipps-University Marburg, 35043 Marburg, Hessen, Germany"},{"name":"Institute for Health Care Management, General Business Administration, Philipps-University Marburg, Universit\u00e4tsstra\u00dfe 24, 35037 Marburg, Hessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9015-3646","authenticated-orcid":false,"given":"Niklas","family":"Gremke","sequence":"additional","affiliation":[{"name":"University Hospital Marburg, Philipps-University Marburg, 35043 Marburg, Hessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9498-9558","authenticated-orcid":false,"given":"Julian","family":"Kreutz","sequence":"additional","affiliation":[{"name":"University Hospital Marburg, Philipps-University Marburg, 35043 Marburg, Hessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Schieffer","sequence":"additional","affiliation":[{"name":"University Hospital Marburg, Philipps-University Marburg, 35043 Marburg, Hessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Timmermann","sequence":"additional","affiliation":[{"name":"University Hospital Marburg, Philipps-University Marburg, 35043 Marburg, Hessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0485-5722","authenticated-orcid":false,"given":"Birgit","family":"Markus","sequence":"additional","affiliation":[{"name":"University Hospital Marburg, Philipps-University Marburg, 35043 Marburg, Hessen, Germany"},{"name":"Institute for Health Care Management, General Business Administration, Philipps-University Marburg, Universit\u00e4tsstra\u00dfe 24, 35037 Marburg, Hessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,25]]},"reference":[{"key":"ref_1","unstructured":"(2022, August 29). 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