{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T02:34:51Z","timestamp":1791513291912,"version":"4.3.4"},"reference-count":119,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T00:00:00Z","timestamp":1612310400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Nutritional deficiencies (malnutrition, cachexia, sarcopenia, and unfavorable changes in the body composition) developing as a side effect of radiotherapy (RT) currently represents a significant but still inaccurately studied clinical problem in cancer patients. The incidence of malnutrition observed in head and neck cancer (HNC) patients in oncological radiology departments can reach 80%. The presence of malnutrition, sarcopenia, and cachexia is associated with an unfavorable prognosis of the disease, higher mortality, and deterioration of the quality of life. Therefore, it is necessary to identify patients with a high risk of both metabolic syndromes. However, the number of studies investigating potential predictive markers for the mentioned purposes is still significantly limited. This literature review summarizes the incidence of nutritional deficiencies in HNC patients prior to therapy and after the commencement of RT, and presents recent perspectives for the prediction of unfavorable nutritional changes developing as a result of applied RT.<\/jats:p>","DOI":"10.3390\/jcm10040574","type":"journal-article","created":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T20:31:51Z","timestamp":1612384311000},"page":"574","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Nutritional Deficiencies in Radiotherapy-Treated Head and Neck Cancer Patients"],"prefix":"10.3390","volume":"10","author":[{"given":"Tomasz","family":"Powr\u00f3zek","sequence":"first","affiliation":[{"name":"Department of Human Physiology, Medical University in Lublin, Radziwi\u0142\u0142owska 11, 20-080 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Dziwota","sequence":"additional","affiliation":[{"name":"Department of Human Physiology, Medical University in Lublin, Radziwi\u0142\u0142owska 11, 20-080 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Ma\u0142ecka-Massalska","sequence":"additional","affiliation":[{"name":"Department of Human Physiology, Medical University in Lublin, Radziwi\u0142\u0142owska 11, 20-080 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,2,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.coms.2018.06.001","article-title":"Epidemiology and Demographics of the Head and Neck Cancer Population","volume":"30","author":"Cohen","year":"2018","journal-title":"Oral Maxillofac. 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