{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T19:40:07Z","timestamp":1771011607357,"version":"3.50.1"},"reference-count":30,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T00:00:00Z","timestamp":1614729600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Psoriasis is an immune-mediated, chronic inflammatory disease, which mainly affects the skin, although it has systemic pathological effects. Comorbidities of psoriasis include ocular disorders, which are often nonspecific or mildly symptomatic. The aim of this study was to show the importance of ocular-disease screening in psoriatic patients using the Ocular Manifestations in Psoriasis Screening (OcMaPS) questionnaire. Patients suffering from moderate-to-severe psoriasis referring at our outpatient-clinic were consecutively enrolled. Each patient was asked to complete a screening questionnaire (OcMaPS). Patients reporting ocular symptoms were referred for an ophthalmological examination. A total of 372 patients were enrolled in the study. Ocular symptoms were detected in 39 patients (10.5%), and 37 patients were referred to ophthalmological examination which confirmed the presence of ocular manifestation in 30 patients. There were three cases (10%) of uveitis, 14 (46.6%) of dry eye and 13 (43.3%) of cataract, in progress or already treated with surgery. In the remaining seven patients, no ocular manifestations were found. Ocular manifestations in psoriatic patients are not rare. It is important to be aware of ocular symptoms in psoriatic patients, screening patients (with a consultation or OcMaPS questionnaire), which leads to earlier diagnosis and treatment.<\/jats:p>","DOI":"10.3390\/jcm10051031","type":"journal-article","created":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T05:10:16Z","timestamp":1614748216000},"page":"1031","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Ocular Manifestations in Psoriasis Screening (OcMaPS) Questionnaire: A Useful Tool to Reveal Misdiagnosed Ocular Involvement in Psoriasis"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4658-7391","authenticated-orcid":false,"given":"Angelo","family":"Ruggiero","sequence":"first","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Via Pansini 5, 80131 Napoli, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Fabbrocini","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Via Pansini 5, 80131 Napoli, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3864-216X","authenticated-orcid":false,"given":"Sara","family":"Cacciapuoti","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Via Pansini 5, 80131 Napoli, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleonora","family":"Cinelli","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Via Pansini 5, 80131 Napoli, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Gallo","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Via Pansini 5, 80131 Napoli, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1803-2046","authenticated-orcid":false,"given":"Matteo","family":"Megna","sequence":"additional","affiliation":[{"name":"Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Via Pansini 5, 80131 Napoli, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"6892","DOI":"10.3748\/wjg.v21.i22.6892","article-title":"Nonalcoholic fatty liver disease, spleen and psoriasis: New aspects of low-grade chronic inflammation","volume":"21","author":"Balato","year":"2015","journal-title":"World J. Gastroenterol."},{"key":"ref_2","first-page":"4673","article-title":"Efficacy and safety of guselkumab in psoriasis patients who failed usteki-numab and\/or anti-interleukin-17 treatment: A real-life 52-week retrospective study","volume":"13","author":"Ruggiero","year":"2020","journal-title":"Dermatol. Ther."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1590\/abd1806-4841.20153038","article-title":"Psoriasis: Classical and emerging comorbidities","volume":"90","author":"Oliveira","year":"2015","journal-title":"An. Bras. Dermatol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.clindermatol.2019.07.029","article-title":"Ocular changes in patients with psoriasis","volume":"37","author":"Demerdjieva","year":"2019","journal-title":"Clin. Dermatol."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Chimenti, M.S., Triggianese, P., Salandri, G., Conigliaro, P., Canofari, C., Caso, F., Costa, L., Nucci, C., Aiello, F., and Cesareo, M. (2020). A Multimodal Eye Assessment in Psoriatic Arthritis Patients sine-Psoriasis: Evidence for a Potential Association with Systemic Inflammation. J. Clin. Med., 9.","DOI":"10.3390\/jcm9030719"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1177\/1203475420952420","article-title":"The Incidence and Prevalence of Uveitis in Psoriasis: A Systematic Review and Me-ta-Analysis","volume":"24","author":"Lam","year":"2020","journal-title":"J. Cutan. Med. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.berh.2016.10.007","article-title":"The eye and inflammatory rheumatic diseases: The eye and rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis","volume":"30","author":"Murray","year":"2016","journal-title":"Best Pr. Res. Clin. Rheumatol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"715","DOI":"10.3109\/08820538.2016.1170161","article-title":"Psoriasis and Psoriatic Ar-thritis-Related Uveitis: Different Ophthalmological Manifestations and Ocular Inflammation Features","volume":"32","author":"Abbouda","year":"2017","journal-title":"Semin. Ophthalmol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1080\/09546630701341949","article-title":"Psoriasis of the face and flexures","volume":"18","author":"Murphy","year":"2007","journal-title":"J. Dermatol. Treat."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1080\/09546634.2019.1577947","article-title":"Ocular findings in patients with psoriasis: Is it related to the side effects of treatment or to psoriasis itself? A case-control study","volume":"31","author":"Ghalamkarpour","year":"2019","journal-title":"J. Dermatol. Treat."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1111\/j.1365-4632.2011.05424.x","article-title":"Ocular findings in patients with psoriasis","volume":"52","author":"Kilic","year":"2013","journal-title":"Int. J. Dermatol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.jaad.2010.10.032","article-title":"Ocular psoriasis","volume":"65","author":"Rehal","year":"2011","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_13","first-page":"649","article-title":"Psoriasis or \u201cpsoriases\u201d?","volume":"148","author":"Balato","year":"2013","journal-title":"G. Ital. Dermatol. Venereol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1159\/000249009","article-title":"Is Eyelid Involvement a Sign of Severe Psoriasis?\/Papulonecrotic Tuberculides on Glans penis","volume":"174","author":"Bernhard","year":"1987","journal-title":"Dermatology"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"219","DOI":"10.5935\/0004-2749.20180044","article-title":"Ocular manifestations of psoriasis","volume":"81","author":"Cruz","year":"2018","journal-title":"Arq. Bras. Oftalmol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1136\/bjophthalmol-2017-310307","article-title":"Tear film and ocular surface assessment in psoriasis","volume":"102","author":"Aragona","year":"2017","journal-title":"Br. J. Ophthalmol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1007\/s10792-020-01437-x","article-title":"The ocular manifestations in IBD screening (OMIS) questionnaire: Pilot study on detection of ocular involvement in inflammatory bowel diseases","volume":"40","author":"Strano","year":"2020","journal-title":"Int. Ophthalmol."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Rendon, A., and Sch\u00e4kel, K. (2019). Psoriasis Pathogenesis and Treatment. Int. J. Mol. Sci., 20.","DOI":"10.3390\/ijms20061475"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Megna, M., Fabbrocini, G., Cinelli, E., Camela, E., and Ruggiero, A. (2020). Guselkumab in moderate to severe psoriasis in routine clinical care: An Italian 44-week real-life experience. J. Dermatol. Treat., 1\u20135.","DOI":"10.1080\/09546634.2020.1800577"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"4144","DOI":"10.1111\/dth.14144","article-title":"Efficacy and safety of risankizumab in psoriasis patients who failed an-ti-IL-17, anti-12\/23 and\/or anti IL-23: Preliminary data of a real-life 16-week retrospective study","volume":"33","author":"Megna","year":"2020","journal-title":"Dermatol. Ther."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.cytogfr.2014.10.009","article-title":"An inflammatory triangle in psoriasis: TNF, type I IFNs and IL-17","volume":"26","author":"Grine","year":"2015","journal-title":"Cytokine Growth Factor Rev."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1001\/archderm.143.12.1493","article-title":"The risk of mortality in patients with psoriasis: Results from a population-based study","volume":"143","author":"Gelfand","year":"2007","journal-title":"Arch. Dermatol."},{"key":"ref_23","first-page":"284","article-title":"The impact of psoriasis on quality of life: Results of a 1998 National Psoriasis Foundation patient-membership survey","volume":"137","author":"Krueger","year":"2001","journal-title":"Arch. Dermatol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1001\/jamaophthalmol.2017.0569","article-title":"Risk of Uveitis Among People with Psoriasis: A Nationwide Cohort Study","volume":"135","author":"Chi","year":"2017","journal-title":"JAMA Ophthalmol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1097\/ICU.0000000000000466","article-title":"Cytokines in uveitis","volume":"29","author":"Weinstein","year":"2018","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"91","DOI":"10.2147\/PTT.S179182","article-title":"Psoriasis and uveitis: Links and risks","volume":"9","author":"Fotiadou","year":"2019","journal-title":"Psoriasis Targets Ther."},{"key":"ref_27","first-page":"210","article-title":"Psoriasis and intraocular inflammation","volume":"77","author":"Knox","year":"1979","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.annder.2009.12.004","article-title":"La phototh\u00e9rapie UVB \u00e0 spectre \u00e9troit dans le psoriasis vulgaire: Utilisation pratique et pr\u00e9-conisations de la Soci\u00e9t\u00e9 Fran\u00e7aise de Photodermatologie Narrow-band UVB therapy in psoriasis vulgaris: Good practice guideline and recommendations of the French Society of Photodermatology","volume":"137","author":"Beani","year":"2010","journal-title":"Ann. Dermatol. Venereol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12348-020-00202-6","article-title":"A review of ocular adverse events of biological anti-TNF drugs","volume":"10","author":"Susanna","year":"2020","journal-title":"J. Ophthalmic. Inflamm. Infect."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.jaad.2008.02.039","article-title":"Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics","volume":"58","author":"Menter","year":"2008","journal-title":"J. Am. Acad. Dermatol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/10\/5\/1031\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:31:44Z","timestamp":1760160704000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/10\/5\/1031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,3]]},"references-count":30,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,3]]}},"alternative-id":["jcm10051031"],"URL":"https:\/\/doi.org\/10.3390\/jcm10051031","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,3]]}}}