{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T12:45:02Z","timestamp":1786365902049,"version":"build-2736575974"},"reference-count":54,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T00:00:00Z","timestamp":1618185600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Hodgkin lymphoma (HL) is a highly-curable malignancy mostly affecting young people. As far as we know, there is no published study that has analyzed personality profiles in HL nor their potential role in lymphomagenesis, natural history, or response to treatment. We aim to explore the personality traits of HL patients, as well as the prevalence of mental disorders and suicide ideas. We retrospectively identified all alive HL patients from three centers (Son Espases and Son Llatzer University Hospitals and Hospital del Mar of Barcelona) for using NEO Five-Factor Inventory (NEO-FFI) and Personality Inventory for DSM-5 Brief Form. Patients with HL showed significantly higher neuroticism scores and lower conscientiousness, extraversion, and openness. Considering maladaptive personality traits, HL patients showed higher levels of detachment and psychoticism. All of these translated into the fact that HL patients showed more than double the prevalence of mental illnesses (41%) and more than triple the prevalence of suicidal ideation or attempts than the general population (15 and 6%, respectively). An exploratory analysis of biomarkers associated with HL personality traits showed that higher scores of neuroticism correlated with more elevated erythrocyte sedimentation rate (ESR) and red cell distribution width (RDW), suggesting a potential link between neuroticism and proinflammatory activity in HL.<\/jats:p>","DOI":"10.3390\/jcm10081631","type":"journal-article","created":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T11:05:06Z","timestamp":1618225506000},"page":"1631","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Analysis of Personality Traits in Patients with Hodgkin Lymphoma"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8752-1575","authenticated-orcid":false,"given":"Fatima","family":"Roso-Bas","sequence":"first","affiliation":[{"name":"Clinical Practice and Biology of the Hematological Malignancies Research Group, IdISBa, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6671-2858","authenticated-orcid":false,"given":"Maria Dolores","family":"Alonso-Llobregat","sequence":"additional","affiliation":[{"name":"Clinical Practice and Biology of the Hematological Malignancies Research Group, IdISBa, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leyre","family":"Bento","sequence":"additional","affiliation":[{"name":"Clinical Practice and Biology of the Hematological Malignancies Research Group, IdISBa, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"},{"name":"Unit of Lymphoma, Department of Hematology, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blanca","family":"Sanchez-Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Hematology, Hospital del Mar, 08003 Barcelona, Spain"},{"name":"IMIM, Hospital del Mar Research Institute, 08003 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1061-9889","authenticated-orcid":false,"given":"Ines","family":"Herraez","sequence":"additional","affiliation":[{"name":"Clinical Practice and Biology of the Hematological Malignancies Research Group, IdISBa, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"},{"name":"Department of Hematology. Son Llatzer University Hospital, 07120 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Garcia-Dilla","sequence":"additional","affiliation":[{"name":"Department of Hematology, Hospital del Mar, 08003 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7621-2913","authenticated-orcid":false,"given":"Catalina","family":"Vallespir","sequence":"additional","affiliation":[{"name":"Service of Psychiatry, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Rado","sequence":"additional","affiliation":[{"name":"Service of Psychiatry, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Psychosocial Support Team, Son Llatzer University Hospital, 07198 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesc","family":"Garcia-Pallarols","sequence":"additional","affiliation":[{"name":"Department of Hematology, Hospital del Mar, 08003 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irache","family":"Aguirre","sequence":"additional","affiliation":[{"name":"Service of Psychiatry, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Bargay","sequence":"additional","affiliation":[{"name":"Clinical Practice and Biology of the Hematological Malignancies Research Group, IdISBa, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"},{"name":"Department of Hematology. Son Llatzer University Hospital, 07120 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7465-6203","authenticated-orcid":false,"given":"Antonia","family":"Sampol","sequence":"additional","affiliation":[{"name":"Clinical Practice and Biology of the Hematological Malignancies Research Group, IdISBa, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Salar","sequence":"additional","affiliation":[{"name":"Department of Hematology, Hospital del Mar, 08003 Barcelona, Spain"},{"name":"IMIM, Hospital del Mar Research Institute, 08003 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9062-077X","authenticated-orcid":false,"given":"Antonio","family":"Gutierrez","sequence":"additional","affiliation":[{"name":"Clinical Practice and Biology of the Hematological Malignancies Research Group, IdISBa, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"},{"name":"Unit of Lymphoma, Department of Hematology, Son Espases University Hospital, 07120 Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,4,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0146-6402(94)00001-8","article-title":"Cancer, personality and stress: Prediction and prevention","volume":"16","author":"Eysenck","year":"1994","journal-title":"Adv. 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