{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T04:29:22Z","timestamp":1781065762136,"version":"3.54.1"},"reference-count":30,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T00:00:00Z","timestamp":1620518400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Introduction: Fungal infections remain a major challenge affecting outcomes after kidney (KT) and liver transplantation (LT). Methods: In this retrospective single center study, the incidence of Candida contamination in renal and hepatic graft preservation solution (PS) was evaluated. In addition, Candida associated infections in recipients and related complications were analyzed. Results: Overall, the PS of 1248 hepatic and 1273 renal grafts were evaluated. The incidence of fungal contamination in the PS of hepatic and renal grafts was 1.2% and 0.86%, respectively. Additionally, the hepatic PS of one patient who underwent a combined liver\u2013kidney transplant had Candida contamination. Candida albicans was the most common organism (70.4%) and 65.4% of the patients received antifungal treatment. Candida-associated complications in the recipients was 19%. Complications in LT patients included Candida peritonitis and Candida sepsis. Two KT recipients with contaminated PS developed a mycotic aneurysm at the anastomotic site resulting in severe bleeding. The 1-year mortality in patients with PS contamination for LT and KT recipients was 33% and 18%, respectively. Although the incidence of fungal contamination of PS was low, contaminated PS was associated with a high mortality. Conclusion: The results of the study suggest that PS should be evaluated for fungal growth.<\/jats:p>","DOI":"10.3390\/jcm10092022","type":"journal-article","created":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T21:32:46Z","timestamp":1620595966000},"page":"2022","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Candida Contamination in Kidney and Liver Organ Preservation Solution: Does It Matter?"],"prefix":"10.3390","volume":"10","author":[{"given":"Sabrina","family":"Stern","sequence":"first","affiliation":[{"name":"Department of General, Visceral and Transplant Surgery, University Duisburg-Essen, 45147 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitri","family":"Bezinover","sequence":"additional","affiliation":[{"name":"Anesthesiology and Perioperative Medicine, Penn State University, PA 17033, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter-M.","family":"Rath","sequence":"additional","affiliation":[{"name":"Institute for Microbiology, University Duisburg-Essen, 45147 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of General, Visceral and Transplant Surgery, University Duisburg-Essen, 45147 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9157-4573","authenticated-orcid":false,"given":"Fuat H.","family":"Saner","sequence":"additional","affiliation":[{"name":"Department of General, Visceral and Transplant Surgery, University Duisburg-Essen, 45147 Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1002\/lt.23640","article-title":"Update on donor-derived infections in liver transplantation","volume":"19","author":"Echenique","year":"2013","journal-title":"Liver Transpl."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1097\/TP.0b013e31816f61a6","article-title":"Pulmonary and blood stream infections in adult living donor and cadaveric liver transplant patients","volume":"85","author":"Saner","year":"2008","journal-title":"Transplantation"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1111\/ajt.12133","article-title":"Donor-derived bacteremia in liver transplant recipients despite antibiotic prophylaxis","volume":"13","author":"Doucette","year":"2013","journal-title":"Am. 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