{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:18:04Z","timestamp":1791231484115,"version":"4.1.0"},"reference-count":27,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T00:00:00Z","timestamp":1622592000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: We aimed to describe red blood cell (RBC) transfusions in the emergency department (ED) with a particular focus on the hemoglobin (Hb) level thresholds that are used in this setting. Methods: This was a cross-sectional study of 12 EDs including all adult patients that received RBC transfusion in January and February 2018. Descriptive statistics were reported. Logistic regression was performed to assess variables that were independently associated with a pre-transfusion Hb level \u2265 8 g\/dL. Results: During the study period, 529 patients received RBC transfusion. The median age was 74 (59\u201385) years. The patients had a history of cancer or hematological disease in 185 (35.2%) cases. Acute bleeding was observed in the ED for 242 (44.7%) patients, among which 145 (59.9%) were gastrointestinal. Anemia was chronic in 191 (40.2%) cases, mostly due to vitamin or iron deficiency or to malignancy with transfusion support. Pre-transfusion Hb level was 6.9 (6.0\u20137.8) g\/dL. The transfusion motive was not notified in the medical chart in 206 (38.9%) cases. In the multivariable logistic regression, variables that were associated with a higher pre-transfusion Hb level (\u22658 g\/dL) were a history of coronary artery disease (OR: 2.09; 95% CI: 1.29\u20133.41), the presence of acute bleeding (OR: 2.44; 95% CI: 1.53\u20133.94), and older age (OR: 1.02\/year; 95% CI: 1.01\u20131.04). Conclusion: RBC transfusion in the ED was an everyday concern and involved patients with heterogeneous medical situations and severity. Pre-transfusion Hb level was rather restrictive. Almost half of transfusions were provided because of acute bleeding which was associated with a higher Hb threshold.<\/jats:p>","DOI":"10.3390\/jcm10112475","type":"journal-article","created":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T10:38:39Z","timestamp":1622630319000},"page":"2475","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6831-0054","authenticated-orcid":false,"given":"Olivier","family":"Peyrony","sequence":"first","affiliation":[{"name":"Emergency Department, H\u00f4pital Saint-Louis, Assistance Publique-H\u00f4pitaux de Paris, 1 Avenue Claude Vellefaux, 75010 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana\u00e9","family":"Gamelon","sequence":"additional","affiliation":[{"name":"Emergency Department, H\u00f4pital Saint-Louis, Assistance Publique-H\u00f4pitaux de Paris, 1 Avenue Claude Vellefaux, 75010 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Brune","sequence":"additional","affiliation":[{"name":"Emergency Department, H\u00f4pital Saint-Louis, Assistance Publique-H\u00f4pitaux de Paris, 1 Avenue Claude Vellefaux, 75010 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8819-0061","authenticated-orcid":false,"given":"Anthony","family":"Chauvin","sequence":"additional","affiliation":[{"name":"Emergency Department, H\u00f4pital Lariboisi\u00e8re, Assistance Publique-H\u00f4pitaux de Paris, 75010 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0129-4322","authenticated-orcid":false,"given":"Daniel Aiham","family":"Ghazali","sequence":"additional","affiliation":[{"name":"Emergency Department, H\u00f4pital Bichat, Assistance Publique-H\u00f4pitaux de Paris, 75018 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0671-6547","authenticated-orcid":false,"given":"Youri","family":"Yordanov","sequence":"additional","affiliation":[{"name":"Emergency Department, H\u00f4pital Saint-Antoine, Assistance Publique-H\u00f4pitaux de Paris, 75012 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aude","family":"Arsicaud","sequence":"additional","affiliation":[{"name":"Emergency Department, H\u00f4pital Andr\u00e9 Mignot, 78300 Versailles, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Gilleron","sequence":"additional","affiliation":[{"name":"H\u00f4pital Henri Mondor, Assistance Publique-H\u00f4pitaux de Paris, 94000 Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Curac","sequence":"additional","affiliation":[{"name":"H\u00f4pital Beaujon, Assistance Publique-H\u00f4pitaux de Paris, 92024 Clichy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Caroline","family":"Richard","sequence":"additional","affiliation":[{"name":"H\u00f4pital Piti\u00e9 Salpetri\u00e8re, Assistance Publique-H\u00f4pitaux de Paris, 75013 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Laure","family":"Feral-Pierssens","sequence":"additional","affiliation":[{"name":"H\u00f4pital Europ\u00e9en Georges Pompidou, Assistance Publique-H\u00f4pitaux de Paris, 75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Villoing","sequence":"additional","affiliation":[{"name":"H\u00f4pital Cochin, Assistance Publique-H\u00f4pitaux de Paris, 75014 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9299-6703","authenticated-orcid":false,"given":"S\u00e9bastien","family":"Beaune","sequence":"additional","affiliation":[{"name":"H\u00f4pital Ambroise Par\u00e9, Assistance Publique-H\u00f4pitaux de Paris, 92100 Boulogne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Goulet","sequence":"additional","affiliation":[{"name":"H\u00f4pital Tenon, Assistance Publique-H\u00f4pitaux de Paris, 75020 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Paul","family":"Fontaine","sequence":"additional","affiliation":[{"name":"Emergency Department, H\u00f4pital Saint-Louis, Assistance Publique-H\u00f4pitaux de Paris, 1 Avenue Claude Vellefaux, 75010 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Fran\u00e7ois","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang Ile de France, 75010 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"France","family":"Pirenne","sequence":"additional","affiliation":[{"name":"Etablissement Fran\u00e7ais du Sang Ile de France, H\u00f4pital Henri Mondor, Assistance Publique-H\u00f4pitaux de Paris, Universit\u00e9 Paris Est Cr\u00e9teil, INSERM U955, Institut Mondor de Recherche Biom\u00e9dicale, 94000 Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/acem.14153","article-title":"Liberal vs Restrictive Hemoglobin Levels as Thresholds for Blood 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