{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:02:49Z","timestamp":1791298969982,"version":"4.1.0"},"reference-count":63,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: The long-term effects of COVID-19 remain largely unclear. This study aims to investigate post-acute health consequences and mortality one year after hospital discharge. Methods: All surviving adult patients who were discharged after hospital admission due to acute COVID-19 in the first wave of the pandemic underwent a comprehensive interview. Functional assessment was performed in patients aged over 65. Clinical and hospital records were reviewed and mortality causes assessed. Results: A total of 587 patients with COVID-19 were discharged from hospital, including 266 after hospital admission and 321 from the emergency room. Mortality within the following year occurred in 34\/266 (12.8%) and 10\/321 (3.1%), respectively, due to causes directly or possibly related to COVID-19 in 20.5% and 25% of patients. Post-COVID-19 syndrome was assessed in 543 patients at one year from discharge. Any clinical complaint was reported by 90.1% of patients who needed hospitalization and 80.4% of those discharged from the emergency room (p = 0.002), with breathlessness (41.6%), tiredness (35.4%), ageusia (30.2%), and anosmia (26.3%) being the most common complaints. Ongoing symptoms attributed to COVID-19 were reported by 66.8% and 49.5% of patients, respectively (p &lt; 0.001). Newly developed COPD, asthma, diabetes, heart failure, and arthritis\u2014as well as worsening of preexisting comorbidities\u2014were found. Conclusions: One-year mortality among survivors of acute COVID-19 was 7.5%. A significant proportion of COVID-19 patients experienced ongoing symptoms at 1 year from onset of the disease.<\/jats:p>","DOI":"10.3390\/jcm10132945","type":"journal-article","created":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T10:03:19Z","timestamp":1625047399000},"page":"2945","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":136,"title":["Long-Term Outcomes of Patients with Coronavirus Disease 2019 at One Year after Hospital Discharge"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8364-1449","authenticated-orcid":false,"given":"Modesto M.","family":"Maestre-Mu\u00f1iz","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Hospital General de Tomelloso, 13700 Ciudad Real, Spain"},{"name":"Department of Medicine and Medical Specialties, Universidad de Alcal\u00e1, 28801 Alcal\u00e1 de Henares, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1006-0958","authenticated-orcid":false,"given":"\u00c1ngel","family":"Arias","sequence":"additional","affiliation":[{"name":"Hospital General La Mancha Centro, Research Unit, Alc\u00e1zar de San Juan, 13600 Ciudad Real, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria La Princesa, 28006 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4573-7711","authenticated-orcid":false,"given":"Emilia","family":"Mata-V\u00e1zquez","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital General de Tomelloso, 13700 Ciudad Real, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Mart\u00edn-Toledano","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital General de Tomelloso, 13700 Ciudad Real, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germ\u00e1n","family":"L\u00f3pez-Larramona","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital General de Tomelloso, 13700 Ciudad Real, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8668-2564","authenticated-orcid":false,"given":"Ana Mar\u00eda","family":"Ruiz-Chicote","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital General de Tomelloso, 13700 Ciudad Real, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1rbara","family":"Nieto-Sandoval","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital General de Tomelloso, 13700 Ciudad Real, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1183-1072","authenticated-orcid":false,"given":"Alfredo J.","family":"Lucendo","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria La Princesa, 28006 Madrid, Spain"},{"name":"Department of Gastroenterology, Hospital General de Tomelloso, 13700 Ciudad Real, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1056\/NEJMoa2001316","article-title":"Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus\u2013Infected Pneumonia","volume":"382","author":"Li","year":"2020","journal-title":"N. 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