{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:34:00Z","timestamp":1791326040531,"version":"4.3.1"},"reference-count":34,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T00:00:00Z","timestamp":1625702400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Purpose: To assess visual performance and quality of life after implantation of diffractive trifocal IOLs with enhanced depth of focus (Acriva Reviol Tri-ED) compared to monofocal IOLs. Setting: Ophthalmology Clinic, Department of Medicine and Science of Ageing, University \u201cG. d\u2019Annunzio\u201d Chieti-Pescara, Italy. Design: Prospective clinical study. Methods: This study comprised 36 eyes of 18 patients with senile cataract candidates for phacoemulsification and implantation of the Acriva Reviol Tri-ED (Group 1\u201318 eyes) and the AcrySof IQ Monofocal IOL SN60WF (Group 2\u201318 eyes). The main outcome measures, over a 6-month follow-up period, were uncorrected and corrected visual acuity at different distances (40, 60 cm and 4 m), defocus curve, contrast sensitivity and wavefront error. Patient satisfaction was evaluated by means of the NEI-RQL-42 questionnaire. Results: At 180 days postoperatively, the difference of the UCDVA and CDVA between the groups was not statistically significant (p = 0.888 and p = 0.843, respectively). The difference between the groups was statistically significant for UCIVA (p = 0.019) and UCNVA (p = 0.036). The mean values of contrast sensitivity under photopic and mesopic conditions were not significantly different between the groups. The RMS of spherical aberration was significantly lower in Group 1 compared to Group 2. The NEI-RQL-42 questionnaire showed statistically significant differences between the groups for the dependence on correction (p &lt; 0.001). Conclusions: The diffractive trifocal IOL with enhanced depth of focus Acriva Reviol Tri-ED was effective in improving functional capacity for intermediate and near vision compared to monofocal IOLs and provided a good quality of vision due to a significant reduction in spherical aberration.<\/jats:p>","DOI":"10.3390\/jcm10143038","type":"journal-article","created":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T10:42:17Z","timestamp":1625740937000},"page":"3038","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Visual Performance and Quality of Life after Femtosecond Laser-Assisted Cataract Surgery with Trifocal IOLs Implantation"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7426-8603","authenticated-orcid":false,"given":"Carla Enrica","family":"Gallenga","sequence":"first","affiliation":[{"name":"Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5383-5173","authenticated-orcid":false,"given":"Rossella","family":"D\u2019Aloisio","sequence":"additional","affiliation":[{"name":"Department of Medicine and Aging Science, Ophthalmology Clinic, University \u201cG. d\u2019Annunzio\u201d of Chieti-Pescara, 66100 Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3357-5532","authenticated-orcid":false,"given":"Erminia","family":"D\u2019Ugo","sequence":"additional","affiliation":[{"name":"Department of Medicine and Aging Science, Ophthalmology Clinic, University \u201cG. d\u2019Annunzio\u201d of Chieti-Pescara, 66100 Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Vecchiarino","sequence":"additional","affiliation":[{"name":"Department of Medicine and Aging Science, Ophthalmology Clinic, University \u201cG. d\u2019Annunzio\u201d of Chieti-Pescara, 66100 Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1625-6305","authenticated-orcid":false,"given":"Luca","family":"Agnifili","sequence":"additional","affiliation":[{"name":"Department of Medicine and Aging Science, Ophthalmology Clinic, University \u201cG. d\u2019Annunzio\u201d of Chieti-Pescara, 66100 Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Beatrice","family":"Simonelli","sequence":"additional","affiliation":[{"name":"Department of Medicine and Aging Science, Ophthalmology Clinic, University \u201cG. d\u2019Annunzio\u201d of Chieti-Pescara, 66100 Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Di Nicola","sequence":"additional","affiliation":[{"name":"Laboratory of Biostatistics, Department of Experimental and Clinical Sciences, University \u201cG. d\u2019Annunzio\u201d of Chieti-Pescara, 66100 Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5311-5184","authenticated-orcid":false,"given":"Lisa","family":"Toto","sequence":"additional","affiliation":[{"name":"Department of Medicine and Aging Science, Ophthalmology Clinic, University \u201cG. d\u2019Annunzio\u201d of Chieti-Pescara, 66100 Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Perri","sequence":"additional","affiliation":[{"name":"Section of Ophthalmology, Department of Neuroscience and Rehabilitation, University of Ferrara, 44121 Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,7,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"426","DOI":"10.3928\/1081597X-20120518-06","article-title":"Distance and near visual acuity improvement after implantation of multifocal intraocular lenses in cataract patients with presbyopia: A systematic review","volume":"28","author":"Agresta","year":"2012","journal-title":"J. Refract. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1444-0938.2012.00815.x","article-title":"Comparative study of Acrysof ReSTOR multifocal intraocular lenses +4.00 D and +3.00 D: Visual performance and wavefront error","volume":"96","author":"Toto","year":"2013","journal-title":"Clin. Exp. Optom."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"754","DOI":"10.3928\/1081597X-20141021-07","article-title":"Comparison of two multifocal intraocular lens designs that differ only in near add","volume":"30","author":"Pedrotti","year":"2014","journal-title":"J. Refract. Surg."},{"key":"ref_4","unstructured":"(2021, May 05). Acriva Reviol Tri-ED IOL Product Brochure: VSY Biotechnology. Available online: http:\/\/www.vsybiotechnology.com\/media\/2016\/08\/Reviol_Tri-ED.pdf."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.jcrs.2007.05.010","article-title":"Visual performance and biocompatibility of two multifocal diffractive IOLs: Six-month comparative study","volume":"33","author":"Toto","year":"2007","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"476","DOI":"10.3928\/1081597X-20130617-06","article-title":"Astigmatism correction with toric IOL: Analysis of visual performance, position, and wavefront error","volume":"29","author":"Toto","year":"2013","journal-title":"J. Refract. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/S0886-3350(99)00147-9","article-title":"Long-term visual results of bifocal intra-ocular lens implantation","volume":"25","author":"Avitabile","year":"1999","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0008-4182(01)80040-5","article-title":"Contrast sensitivity and depth of focus with aspheric multifocal versus conventional monofocal intraocular lens","volume":"36","author":"Dadeya","year":"2001","journal-title":"Can. J. Ophthalmol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0886-3350(03)00664-3","article-title":"Refractive outcomes after bilateral multifocal intraocular lens implantation","volume":"30","author":"Jaramillo","year":"2004","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0161-6420(03)00862-5","article-title":"Visual Performance with Multifocal Intraocular Lenses Mesopic Contrast Sensitivity under Distance and Near Conditions","volume":"111","author":"Espana","year":"2004","journal-title":"Ophthalmology"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1016\/j.jcrs.2004.04.049","article-title":"Quality of vision after AMO Array multifocal intraocular lens implantation","volume":"30","author":"Nida","year":"2004","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1364\/JOSAA.20.001841","article-title":"Optical aberrations of intraocular lenses measured in vivo and in vitro","volume":"20","author":"Barbero","year":"2003","journal-title":"J. Opt. Soc. Am. A Opt. Image Sci. Vis."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jcrs.2013.06.025","article-title":"Outcomes of a new diffractive trifocal intraocular lens","volume":"40","author":"Mojzis","year":"2014","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1007\/s00417-010-1424-8","article-title":"Initial results of trifocal diffractive IOL implantation","volume":"248","author":"Voskresenskaya","year":"2010","journal-title":"Graefes. Arch. Clin. Exp. Ophthalmol."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Acar, B.T., Duman, E., and Simsek, S. (2016). Clinical outcomes of a new diffractive trifocal intraocular lens with Enhanced Depth of Focus (EDOF). BMC Ophthalmol., 16.","DOI":"10.1186\/s12886-016-0389-8"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Carballo-Alvarez, J., Vazquez-Molini, J.M., Sanz-Fernandez, J.C., Garcia-Bella, J., Polo, V., Garcia-Feijoo, J., and Martinez-de-la-Casa, J.M. (2015). Visual outcomes after bilateral trifocal diffractive intraocular lens implantation. BMC Ophthalmol., 15.","DOI":"10.1186\/s12886-015-0012-4"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jcrs.2012.09.017","article-title":"Visual outcomes and subjective experience after bilateral implantation of a new diffractive trifocal intraocular lens","volume":"39","author":"Sheppard","year":"2013","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.2147\/OPTH.S44415","article-title":"Visual performance after the implantation of a new trifocal intraocular lens","volume":"7","author":"Vryghem","year":"2013","journal-title":"Clin. Ophthalmol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.2147\/OPTH.S32343","article-title":"Visual and refractive outcomes after implantation of a fully diffractive trifocal lens","volume":"6","author":"Cochener","year":"2012","journal-title":"Clin. Ophthalmol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ajo.2015.09.030","article-title":"Trifocal Intraocular Lens Implantation to Treat Visual Demands in Various Distances Following Lens Removal","volume":"161","author":"Kohnen","year":"2016","journal-title":"Am. J. Ophthalmol."},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Kretz, F.T., Muller, M., Gerl, M., Gerl, R.H., and Auffarth, G.U. (2015). Binocular function to increase visual outcome in patients implanted with a diffractive trifocal intraocular lens. BMC Ophthalmol., 15.","DOI":"10.1186\/s12886-015-0089-9"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"962891","DOI":"10.1155\/2015\/962891","article-title":"Clinical Outcomes after Binocular Implantation of a New Trifocal Diffractive Intraocular Lens","volume":"2015","author":"Kretz","year":"2015","journal-title":"J. Ophthalmol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1016\/j.jcrs.2014.11.050","article-title":"Implantation of a diffractive trifocal intraocular lens: One-year follow-up","volume":"41","author":"Mojzis","year":"2015","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s40662-017-0076-8","article-title":"Visual and refractive outcomes following implantation of a new trifocal intraocular lens","volume":"4","author":"Lawless","year":"2017","journal-title":"Eye Vis."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Garc\u00eda-P\u00e9rez, J.L., Gros-Otero, J., S\u00e1nchez-Ramos, C., Bl\u00e1zquez, V., and Contreras, I. (2017). Short term visual outcomes of a new trifocal intraocular lens. BMC Ophthalmol., 17.","DOI":"10.1186\/s12886-017-0462-y"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"666","DOI":"10.3928\/1081597X-20140903-06","article-title":"Comparative analysis of the visual performance after cataract surgery with implantation of a bifocal or trifocal diffractive IOL","volume":"30","author":"Mojzis","year":"2014","journal-title":"J. Refract. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1590\/S0004-27492009000400017","article-title":"Comparison between OPD-Scan results and visual outcomes of monofocal and multifocal intraocular lenses","volume":"72","author":"Hida","year":"2009","journal-title":"Arq. Bras. Oftalmol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.jcrs.2017.03.037","article-title":"Visual performance after bilateral implantation of 2 new presbyopia-correcting intraocular lenses: Trifocal versus extended range of vision","volume":"43","author":"Monaco","year":"2017","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"280","DOI":"10.3928\/1081597X-20080301-10","article-title":"Problems in the measurement of wavefront aberration for eyes implanted with diffractive bifocal and multifocal intraocular lenses","volume":"24","author":"Charman","year":"2008","journal-title":"J. Refract. Surg."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.jcrs.2007.11.038","article-title":"Limited accuracy of Hartmann\u2013Shack wavefront sensing in eyes with diffractive multifocal IOLs","volume":"34","author":"Gatinel","year":"2008","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_31","first-page":"805","article-title":"Comparison of visual outcomes and subjective visual quality after bilateral implantation of a diffractive trifocal intraocular lens and blended implantation of apodized diffractive bifocal intraocular lenses","volume":"10","author":"Gundersen","year":"2016","journal-title":"Clin. Ophthalmol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/j.jcrs.2015.08.011","article-title":"Comparison of a trifocal intraocular lens with a +3.0 D bifocal IOL: Results of a prospective randomized clinical trial","volume":"41","author":"Jonker","year":"2015","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"146","DOI":"10.3928\/1081597X-20160114-01","article-title":"Prospective clinical comparison of patient outcomes following implantation of trifocal or bifocal intraocular lenses","volume":"32","author":"Cochener","year":"2016","journal-title":"J. Refract. Surg."},{"key":"ref_34","first-page":"455","article-title":"Comparison of visual outcomes after implantation of diffractive trifocal toric intraocular lens and a diffractive apodized bifocal toric intraocular lens","volume":"10","author":"Gundersen","year":"2016","journal-title":"Clin. Ophthalmol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/10\/14\/3038\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T06:27:40Z","timestamp":1760164060000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/10\/14\/3038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,8]]},"references-count":34,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2021,7]]}},"alternative-id":["jcm10143038"],"URL":"https:\/\/doi.org\/10.3390\/jcm10143038","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,8]]}}}