{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T04:53:23Z","timestamp":1792904003270,"version":"4.5.0"},"reference-count":27,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T00:00:00Z","timestamp":1626220800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Compliance is highly relevant during clear aligner therapy (CAT). In this retrospective cohort study, we assessed compliance and associated covariates in a large cohort of CAT patients. A comprehensive sample of 2644 patients (75.0% females, 25.0% males, age range 18\u201364 years, median 27 years), all receiving CAT with PlusDental (Berlin, Germany) finished in 2019, was analyzed. Covariates included demographic ones (age, gender) as well as self-reported questionnaire-obtained ones (satisfaction with ones\u2019 smile prior treatment, the experience of previous orthodontic therapy). The primary outcome was compliance: Based on patients\u2019 consistent use of the mobile application for self-report and aligner wear time of \u226522 h, patients were classified as fully compliant, fairly compliant, or poorly compliant. Chi-square test was used to compare compliance in different subgroups. A total of 953\/2644 (36.0%) of patients showed full compliance, 1012\/2644 (38.3%) fair compliance, and 679\/2644 (25.7%) poor compliance. Males were significantly more compliant than females (p = 0.000014), as were patients without previous orthodontic treatment (p = 0.023). Age and self-perceived satisfaction with ones\u2019 smile prior to treatment were not sufficiently associated with compliance (p &gt; 0.05). Our findings could be used to guide practitioners towards limitedly compliant individuals, allowing early intervention.<\/jats:p>","DOI":"10.3390\/jcm10143103","type":"journal-article","created":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T10:13:42Z","timestamp":1626257622000},"page":"3103","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":80,"title":["Factors Influencing Patient Compliance during Clear Aligner Therapy: A Retrospective Cohort Study"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5418-5683","authenticated-orcid":false,"given":"Lan Huong","family":"Timm","sequence":"first","affiliation":[{"name":"Sunshine Smile, Windscheidstra\u00dfe 18, 10627 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8992-4629","authenticated-orcid":false,"given":"Gasser","family":"Farrag","sequence":"additional","affiliation":[{"name":"Sunshine Smile, Windscheidstra\u00dfe 18, 10627 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Baxmann","sequence":"additional","affiliation":[{"name":"Orthodentix, Arnoldstrasse 13 b, 47906 Kempen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1223-1669","authenticated-orcid":false,"given":"Falk","family":"Schwendicke","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnostics, Digital Health and Health Services Research, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, A\u00dfmannshauser Stra\u00dfe 4-6, 14197 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,7,14]]},"reference":[{"key":"ref_1","first-page":"163","article-title":"Communication through telemedicine: Home teleassistance in orthodontics","volume":"10","author":"Favero","year":"2009","journal-title":"Eur. 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