{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:45:26Z","timestamp":1787244326371,"version":"build-2736575974"},"reference-count":27,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2021,7,18]],"date-time":"2021-07-18T00:00:00Z","timestamp":1626566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Introduction: During atrial fibrillation (AF) ablation, it is generally considered that atrial tachycardia (AT) episodes are a consequence of ablation.\u00a0Objective: To investigate the spatial relationship between localized AT episodes and dispersion\/ablation regions during persistent AF ablation procedures.\u00a0Methods: We analyzed 72 consecutive patients who presented for an index persistent AF ablation procedure guided by the presence of spatiotemporal dispersion of multipolar electrograms. We characterized spontaneous or post-ablation ATs\u2019 mechanism and location in regard to dispersion regions and ablation lesions. Results: In 72 consecutive patients admitted for persistent AF ablation, 128 ATs occurred in 62 patients (1.9 \u00b1 1.1\/patient). Seventeen ATs were recorded before any ablation. In a total of 100 ATs with elucidated mechanism, there were 58 localized sources and 42 macro-reentries. A large number of localized ATs arose from regions exhibiting dispersion during AF (n = 49, 84%). Importantly, these ATs\u2019 locations were generally remote from the closest ablation lesion (n = 42, 72%). Conclusions: In patients undergoing a persistent AF ablation procedure guided by the presence of spatiotemporal dispersion of multipolar electrograms, localized ATs originate within dispersion regions but remotely from the closest ablation lesion. These results suggest that ATs represent a stabilized manifestation of co-existing AF drivers rather than ablation-induced arrhythmias.<\/jats:p>","DOI":"10.3390\/jcm10143170","type":"journal-article","created":{"date-parts":[[2021,7,18]],"date-time":"2021-07-18T21:16:48Z","timestamp":1626643008000},"page":"3170","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Localized Atrial Tachycardia and Dispersion Regions in Atrial Fibrillation: Evidence of Spatial Concordance"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1472-0773","authenticated-orcid":false,"given":"Edouard","family":"Gitenay","sequence":"first","affiliation":[{"name":"H\u00f4pital Saint Joseph, 26 bd de Louvain, 13008 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9ment","family":"Bars","sequence":"additional","affiliation":[{"name":"H\u00f4pital Saint Joseph, 26 bd de Louvain, 13008 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Bremondy","sequence":"additional","affiliation":[{"name":"H\u00f4pital Saint Joseph, 26 bd de Louvain, 13008 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anis","family":"Ayari","sequence":"additional","affiliation":[{"name":"H\u00f4pital Saint Joseph, 26 bd de Louvain, 13008 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Maillot","sequence":"additional","affiliation":[{"name":"H\u00f4pital Saint Joseph, 26 bd de Louvain, 13008 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Baptiste","sequence":"additional","affiliation":[{"name":"H\u00f4pital Saint Joseph, 26 bd de Louvain, 13008 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Taormina","sequence":"additional","affiliation":[{"name":"H\u00f4pital Saint Joseph, 26 bd de Louvain, 13008 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aicha","family":"Fofana","sequence":"additional","affiliation":[{"name":"H\u00f4pital Saint Joseph, 26 bd de Louvain, 13008 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Siame","sequence":"additional","affiliation":[{"name":"H\u00f4pital Saint Joseph, 26 bd de Louvain, 13008 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Kalifa","sequence":"additional","affiliation":[{"name":"H\u00f4pital Saint Joseph, 26 bd de Louvain, 13008 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Seitz","sequence":"additional","affiliation":[{"name":"H\u00f4pital Saint Joseph, 26 bd de Louvain, 13008 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,7,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1016\/j.jacc.2003.12.054","article-title":"A new approach for catheter ablation of atrial fibrillation: Mapping of the electrophysiologic substrate","volume":"43","author":"Nademanee","year":"2004","journal-title":"J. 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