{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:22:05Z","timestamp":1760235725571,"version":"build-2065373602"},"reference-count":17,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T00:00:00Z","timestamp":1631836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: We evaluated the safety and efficacy of endoscopic cyclophotocoagulation (ECP) for eyes with primary open-angle glaucoma (POAG). Methods: We included a total of 104 pseudophakic eyes treated with ECP. Visual acuity and intraocular pressure (IOP, mmHg) measurements were evaluated preoperatively and on days 1 and 7 and 2 and 12 months postoperatively. IOP \u2264 15 or \u226530% reduction from baseline were defined as therapeutic success. Results: The mean baseline IOP was 23.89 \u00b1 8.63, and it decreased significantly at the day 1 (16.25 \u00b1 7.32, p &lt; 0.0001), day 7 (17.81 \u00b1 6.37, p &lt; 0.0001), 2nd month (17.77 \u00b1 8.54, p &lt; 0.0001) and 12th month (16.42 \u00b1 7.05, p &lt; 0.0001) follow-up visits. Therapeutic success was achieved in 55 (61.80%) eyes at the 12-month follow-up. Patients with POAG duration longer than 10 years or those using alpha agonist eye drops had a lower rate of therapeutic success (odds ratio: 0.52, 95% CI = 0.32\u20130.85, p &lt; 0.05 and odds ratio: 0.92, 95% CI = 0.55\u20130.95, p = 0.024, respectively). A longer disease course was associated with higher IOP values (Rs =+0.281; p = 0.024) postoperatively. The number of antiglaucoma medications decreased significantly from 2.55 \u00b1 1.16 to 2.11 \u00b1 1.14 (p = 0.003). The ECP complications included a minor IOP increase (9.37%), pupil irregularity (15.73%), and the presence of fibrin (3.29%). Conclusions: The ECP is an effective and safe option, especially in eyes with a shorter glaucoma course.<\/jats:p>","DOI":"10.3390\/jcm10184212","type":"journal-article","created":{"date-parts":[[2021,9,18]],"date-time":"2021-09-18T00:13:47Z","timestamp":1631924027000},"page":"4212","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Safety and Efficacy of Isolated Endoscopic Cyclophotocoagulation in Pseudophakic Patients with Primary Open-Angle Glaucoma\u201412-Month Follow-Up"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9416-5030","authenticated-orcid":false,"given":"Marta P.","family":"Wi\u0105cek","sequence":"first","affiliation":[{"name":"First Department of Ophthalmology, Pomeranian Medical University, Powst. Wlkp. 72, 70-111 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Miszczuk","sequence":"additional","affiliation":[{"name":"First Department of Ophthalmology, Pomeranian Medical University, Powst. Wlkp. 72, 70-111 Szczecin, Poland"},{"name":"\u201cDom Lekarski\u201d Medical Center, ul. Rydla 37, 70-783 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrzej","family":"Lipi\u0144ski","sequence":"additional","affiliation":[{"name":"\u201cDom Lekarski\u201d Medical Center, ul. Rydla 37, 70-783 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Machali\u0144ska","sequence":"additional","affiliation":[{"name":"First Department of Ophthalmology, Pomeranian Medical University, Powst. Wlkp. 72, 70-111 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.2147\/OPTH.S80490","article-title":"Minimally invasive glaucoma surgery: Current status and future prospects","volume":"10","author":"Coleman","year":"2016","journal-title":"Clin. Ophthalmol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1159\/000458496","article-title":"When Should We Give Up Filtration Surgery: Indications, Techniques and Results of Cyclodestruction","volume":"59","author":"Solano","year":"2017","journal-title":"Dev. Ophthalmol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1007\/s10792-016-0411-4","article-title":"Refractive outcome of combined phacoemulsification and endoscopic cyclophotocoagulation","volume":"37","author":"Kang","year":"2016","journal-title":"Int. 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Ophthalmol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jcrs.2015.07.046","article-title":"Effect of endocyclophotocoagulation on refractive outcomes in angle-closure eyes after phacoemulsification and posterior chamber intraocular lens implantation","volume":"42","author":"Wang","year":"2016","journal-title":"J. Cataract. Refract. Surg."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1097\/IJG.0b013e3180575215","article-title":"One-site Versus Two-site Endoscopic Cyclophotocoagulation","volume":"16","author":"Kahook","year":"2007","journal-title":"J. Glaucoma"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/10\/18\/4212\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:01:13Z","timestamp":1760166073000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/10\/18\/4212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,17]]},"references-count":17,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2021,9]]}},"alternative-id":["jcm10184212"],"URL":"https:\/\/doi.org\/10.3390\/jcm10184212","relation":{},"ISSN":["2077-0383"],"issn-type":[{"type":"electronic","value":"2077-0383"}],"subject":[],"published":{"date-parts":[[2021,9,17]]}}}