{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T22:23:52Z","timestamp":1772749432747,"version":"3.50.1"},"reference-count":45,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T00:00:00Z","timestamp":1631836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>People with multiple sclerosis (MS) were expected to be particularly affected by the COVID-19 pandemic. The purpose of the study was to evaluate the burden of pandemic, perceived by Polish MS patients, with regard to major contributing factors. The survey, conducted in August\/September 2020, included: Perceived Stress Scale (PSS-10), Coping Orientations to Problems Experienced (Brief\u2013COPE), questions on demographic data, MS characteristics, and health-related and social aspects of pandemic burden. Relationships were searched between PSS-10 and Mini-COPE results and other analyzed items, using U Mann\u2013Whitney test, Kruskal\u2013Wallis ANOVA rank test and Spearman rank correlation. The survey was answered by 287 MS patients (208 female, 79 male, aged 21\u201369 years). Since March 2020, 2.4% of respondents had been positive for COVID-19 and 5.2% had undergone a quarantine. Mean PSS-10 score was 19.99, with moderate or high level of stress in 83.3% of respondents. Problem-focused strategies were more frequently used than emotion-focused strategies (1.76 vs. 1.16). Higher PSS-10 score was associated with comorbidities (H = 4.28), increase in major MS symptoms during the pandemic (21.92 vs. 18.06), experience of healthcare limitations (21.12 vs. 17.98), work-related (22.58 vs. 18.69), financial (22.70 vs. 18.83) and family-related problems (22.54 vs. 17.73) due to pandemic restrictions. A coping model was associated with functional disability and limitations to daily activities (H = 7.81). During the first stage of the pandemic, MS patients reported increased level of stress and preferred problem-focused coping. The level of stress and coping showed more relationships with pandemic impact upon social issues than with MS-related variables.<\/jats:p>","DOI":"10.3390\/jcm10184215","type":"journal-article","created":{"date-parts":[[2021,9,18]],"date-time":"2021-09-18T00:13:47Z","timestamp":1631924027000},"page":"4215","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Burden of COVID-19 Pandemic Perceived by Polish Patients with Multiple Sclerosis"],"prefix":"10.3390","volume":"10","author":[{"given":"Anna","family":"Pokryszko-Dragan","sequence":"first","affiliation":[{"name":"Department of Neurology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justyna","family":"Chojdak-\u0141ukasiewicz","sequence":"additional","affiliation":[{"name":"Department of Neurology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Gruszka","sequence":"additional","affiliation":[{"name":"Department of Neurology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcin","family":"Paw\u0142owski","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Wroclaw Medical University, Wybrze\u017ce Pasteura 10, 50-367 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Paw\u0142owski","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Wroclaw Medical University, Wybrze\u017ce Pasteura 10, 50-367 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Rudkowska-Mytych","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Wroclaw Medical University, Wybrze\u017ce Pasteura 10, 50-367 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna","family":"Rymaszewska","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Wroclaw Medical University, Wybrze\u017ce Pasteura 10, 50-367 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u0142awomir","family":"Budrewicz","sequence":"additional","affiliation":[{"name":"Department of Neurology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"102618","DOI":"10.1016\/j.msard.2020.102618","article-title":"Distress and risk perception in people living with multiple sclerosis during the early phase of the COVID-19 pandemic","volume":"47","author":"Alschuler","year":"2021","journal-title":"Mult. 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