{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:43:20Z","timestamp":1779918200775,"version":"3.53.1"},"reference-count":27,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T00:00:00Z","timestamp":1632787200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Aims: We aimed to prospectively investigate the effectiveness of a standardized follow-up for AF-detection after common atrial flutter (cAFL) ablation. Methods: A total of 309 patients after cAFL ablation without known AF, from 5 centers, and at least one completed, standardized follow-up at 3, 6 and 12 months, including a 24 h Holter-electrocardiogram (ECG), were included. The primary outcome was incident atrial fibrillation (AF), or atrial tachycardia (AT). Predictors were investigated by Cox proportional-hazards models. Results: The mean age was 67.9 years; 15.2% were female and the mean CHA2DS2-VASc (Congestive heart failure, Hypertension, Age, Diabetes, Stroke, Vascular disease, Sex category) score was 2.4 points. The great majority of patients (90.3%) were anticoagulated. Over a mean follow-up of 12.2 months with a standardized approach, AF\/AT was detected in 73 patients, corresponding to 11.7% at 3 months, 18.4% at 6 months and 28.2% at 12 months of follow-up. AF was found in 64 patients, AT in 9 and both in 2 patients. Occurrence of AF was recorded in 40 (60.6%) patients by Holter-ECG and in the remaining 26 (39.4%) by clinical follow-up only. There was no difference in male versus female (p = 0.08), or in younger versus older patients (p = 0.96) for AF\/AT detection. Only coronary artery disease (hazard ratio [95% confidence intervals] 1.03 [1.01\u20131.05], p = 0.01) was associated with the primary outcome. Conclusions: AF or AT was detected in a large proportion of cAFL patients after cavotricuspid-isthmus (CTI) ablation, using a standardized follow-up over 1 year. This standardized screening can be easily implemented with high patient acceptance. The high proportion of post-ablation AF needs to be taken into consideration when deciding on long-term oral anticoagulation.<\/jats:p>","DOI":"10.3390\/jcm10194453","type":"journal-article","created":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T21:38:09Z","timestamp":1632865089000},"page":"4453","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Prospective Evaluation of a Standardized Screening for Atrial Fibrillation after Ablation of Cavotricuspid Isthmus Dependent Atrial Flutter"],"prefix":"10.3390","volume":"10","author":[{"given":"Philipp","family":"Krisai","sequence":"first","affiliation":[{"name":"Cardiovascular Research Institute Basel, Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland"},{"name":"Electrophysiology and Ablation Unit, Centre Hospitalier Universitaire de Bordeaux, 33600 Bordeaux-Pessac, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0827-1329","authenticated-orcid":false,"given":"Laurent","family":"Roten","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Zeljkovic","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Sestre Milosrdnice, 10000 Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9187-7681","authenticated-orcid":false,"given":"Nikola","family":"Pavlovic","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Sestre Milosrdnice, 10000 Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Ammann","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cantonal Hospital St. Gallen, 9007 St. Gallen, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7197-8415","authenticated-orcid":false,"given":"Tobias","family":"Reichlin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Auf der Maur","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Streicher","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Institute Basel, Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland"},{"name":"Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Knecht","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Institute Basel, Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland"},{"name":"Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"K\u00fchne","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Institute Basel, Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland"},{"name":"Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Osswald","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Institute Basel, Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland"},{"name":"Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Novak","sequence":"additional","affiliation":[{"name":"Herz-und Nierenzentrum Aare, 4500 Solothurn, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Sticherling","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Institute Basel, Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland"},{"name":"Department of Cardiology, University Hospital Basel, 4031 Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.jacep.2016.03.014","article-title":"Incidence of Atrial Fibrillation After Atrial Flutter Ablation","volume":"2","author":"Maskoun","year":"2016","journal-title":"JACC Clin. 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