{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:30:11Z","timestamp":1762900211774,"version":"build-2065373602"},"reference-count":37,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T00:00:00Z","timestamp":1635120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Mucopolysaccharidosis (MPS) is a rare congenital lysosomal storage disorder with complex airways. High anterior larynx is assessed by thyromental distance (TMD) nasendoscopy. A simpler method to assess this hyoid bone is described. The distance between the central-hyoid and symphysis of the mandible (hyo-mental distance; HMD) and inclination of this line to the horizontal axis (hyo-mental angle; HMA) in neutrally positioned patients is investigated. Methods: HMA, HMD in MPS, and non-MPS were compared, and their correlation with height and weight were assessed. Results: 50 adult MPS patients (M = 32, F = 18, age range = 19\u201366 years; mean BMI = 26.8 kg\/m2) of MPS I, II, III, IV, and VI were compared with 50 non-MPS (M = 25, F = 25; age range = 22\u201384 years; mean BMI = 26.5 kg\/m2). Mean HMA in MPS was 25.72\u00b0 (\u221210 to +50) versus 2.42\u00b0 (\u221235 to +28) in non-MPS. Mean HMD was 46.5 (25.7\u201366) millimeters in MPS versus 41.8 (27\u201360.3) in non-MPS. HMA versus height and weight showed a moderate correlation (r = \u22120.4, p &lt; 0.05) in MPS and no significant correlation (r &lt; 0.4, p &gt; 0.05) in non-MPS. HMD versus height and weight showed no correlation (r &lt; 0.4, p &gt; 0.05) in both groups. Conclusions: HMA seems more acute in MPS despite nearly the same HMD as non-MPS, signifying a high larynx, which may be missed by TMD.<\/jats:p>","DOI":"10.3390\/jcm10214924","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T21:40:21Z","timestamp":1635198021000},"page":"4924","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hyo-Mental Angle and Distance: An Important Adjunct in Airway Assessment of Adult Mucopolysaccharidosis"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9495-7764","authenticated-orcid":false,"given":"Chaitanya","family":"Gadepalli","sequence":"first","affiliation":[{"name":"Ear Nose and Throat Department, Salford Royal NHS Foundation Trust, Manchester M6 8HD, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0148-6332","authenticated-orcid":false,"given":"Karolina M.","family":"Stepien","sequence":"additional","affiliation":[{"name":"Adult Inherited Metabolic Department, Salford Royal NHS Foundation Trust, Manchester M6 8HD, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Govind","family":"Tol","sequence":"additional","affiliation":[{"name":"Anaesthetics Department, Salford Royal NHS Foundation Trust, Manchester M6 8HD, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Mehta, A.B., and Winchester, B. 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