{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T17:43:06Z","timestamp":1769881386775,"version":"3.49.0"},"reference-count":43,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T00:00:00Z","timestamp":1639612800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Anterior cervical corpectomy and plating has been recognized as a valuable approach for the surgical treatment of cervical spinal metastases. This study aimed to report the surgical, clinical and radiological outcomes of anterior carbon-PEEK instrumentations for cervical spinal metastases. Methods: Demographical, clinical, surgical and radiological data were collected from 2017 to 2020. The Neck Disability Index (NDI) questionnaire for neck pain, EORTC QLQ-C30 questionnaire for quality of life, Nurick scale for myelopathy and radiological parameters (segmental Cobb angle and cervical lordosis) were collected before surgery, at 6 weeks postoperatively and follow-up. Results: Seventeen patients met inclusion criteria. Mean age was 60.9 \u00b1 7.6 years and mean follow-up was 12.9 \u00b1 4.0 months. The NDI (55.4 \u00b1 11.7 to 25.1 \u00b1 5.4, p &lt; 0.001) scores and the EORTC QLQ-C30 global health\/QoL significantly improved postoperatively and at the last follow-up. The segmental Cobb angle (10.7\u00b0 \u00b1 5.6 to 3.1\u00b0 \u00b1 2.2, p &lt; 0.001) and cervical lordosis (0.9\u00b0 \u00b1 6.7 to \u22126.2 \u00b1 7.8, p = 0.002) significantly improved postoperatively. Only one minor complication (5.9%) was recorded. Conclusions: Carbon\/PEEK implants represent a safe alternative to commonly used titanium ones and should be considered in cervical spinal metastases management due to their lower artifacts in postoperative imaging and radiation planning. Further larger comparative and cost-effectiveness studies are needed to confirm these results.<\/jats:p>","DOI":"10.3390\/jcm10245910","type":"journal-article","created":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T11:27:36Z","timestamp":1639654056000},"page":"5910","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Anterior Corpectomy and Plating with Carbon-PEEK Instrumentation for Cervical Spinal Metastases: Clinical and Radiological Outcomes"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5087-6006","authenticated-orcid":false,"given":"Sokol","family":"Trungu","sequence":"first","affiliation":[{"name":"Neurosurgery Unit, Cardinale G. Panico Hospital, 73039 Tricase, Italy"},{"name":"NESMOS Department, Sant\u2019Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5110-8386","authenticated-orcid":false,"given":"Luca","family":"Ricciardi","sequence":"additional","affiliation":[{"name":"NESMOS Department, Sant\u2019Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Forcato","sequence":"additional","affiliation":[{"name":"Neurosurgery Unit, Cardinale G. Panico Hospital, 73039 Tricase, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Scollato","sequence":"additional","affiliation":[{"name":"Neurosurgery Unit, Cardinale G. Panico Hospital, 73039 Tricase, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Minniti","sequence":"additional","affiliation":[{"name":"Radiation Oncology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy"},{"name":"IRCCS Neuromed, 86077 Pozzilli (IS), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Miscusi","sequence":"additional","affiliation":[{"name":"NESMOS Department, Sant\u2019Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonino","family":"Raco","sequence":"additional","affiliation":[{"name":"NESMOS Department, Sant\u2019Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S131","DOI":"10.1093\/neuros\/nyw084","article-title":"Spine Oncology\u2014Metastatic Spine Tumors","volume":"80","author":"Choi","year":"2017","journal-title":"Neurosurgery"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"94","DOI":"10.3171\/2010.3.SPINE09202","article-title":"Diagnosis and management of metastatic spine disease","volume":"13","author":"Sciubba","year":"2010","journal-title":"J. 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