{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:56Z","timestamp":1789689656674,"version":"4.0.1"},"reference-count":58,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T00:00:00Z","timestamp":1642550400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Over the last 15 years, the management of aortic valve disease has been changed by transcatheter aortic valve replacement, which has become the standard of care across the entire spectrum of surgical risk. As a result of continuous evolution of this technique, several next-generation transcatheter heart valves (THVs) have been developed to minimize procedural complications and improve patient outcomes. This review aims to provide an update on the new generation THVs and delivery systems.<\/jats:p>","DOI":"10.3390\/jcm11030499","type":"journal-article","created":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T08:20:57Z","timestamp":1642580457000},"page":"499","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["An Update on New Generation Transcatheter Aortic Valves and Delivery Systems"],"prefix":"10.3390","volume":"11","author":[{"given":"Gloria","family":"Santangelo","sequence":"first","affiliation":[{"name":"San Paolo Hospital, Division of Cardiology, Department of Health Sciences, University of Milan, Via Antonio di Rudin\u00ec 8, 20142 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Ielasi","sequence":"additional","affiliation":[{"name":"Clinical and Interventional Cardiology Unit, Istituto Clinico Sant\u2019Ambrogio, Via Faravelli 16, 20149 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano","family":"Pellicano","sequence":"additional","affiliation":[{"name":"Clinical and Interventional Cardiology Unit, Istituto Clinico Sant\u2019Ambrogio, Via Faravelli 16, 20149 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azeem","family":"Latib","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, 111 210th Street, Bronx, NY 10467, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Tespili","sequence":"additional","affiliation":[{"name":"Clinical and Interventional Cardiology Unit, Istituto Clinico Sant\u2019Ambrogio, Via Faravelli 16, 20149 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2839-0373","authenticated-orcid":false,"given":"Francesco","family":"Donatelli","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Center, Istituto Clinico Sant\u2019Ambrogio, University of Milan, Via Faravelli 16, 20149 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.1161\/01.CIR.0000047200.36165.B8","article-title":"Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis: First human case description","volume":"106","author":"Cribier","year":"2002","journal-title":"Circulation"},{"key":"ref_2","first-page":"e72","article-title":"2020 ACC\/AHA Guideline for the Management of Patients with Valvular Heart Disease: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"143","author":"Otto","year":"2021","journal-title":"Circulation"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1093\/eurheartj\/ehy244","article-title":"Transcatheter aortic valve implantation: Current status and future perspectives","volume":"39","author":"Cahill","year":"2018","journal-title":"Eur. 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