{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:31:58Z","timestamp":1790659918523,"version":"4.1.0"},"reference-count":28,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T00:00:00Z","timestamp":1643500800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objective: The magnitude and direction of effects on pregnancy outcomes of the lockdown imposed during COVID-19 have been uncertain and debated. Therefore, we aimed to quantify delivery and perinatal outcomes during the first nationwide lockdown due to the COVID-19 pandemic compared with the same durations of time for the pre- and post-lockdown periods. Study design: This was a retrospective cohort study of six university hospital maternity units distributed across France, each of which serves as the obstetric care referral unit within its respective perinatal network. Maternal and perinatal outcomes were compared between the lockdown period and same-duration (i.e., 55-day) periods before and after the 2020 lockdown (pre-lockdown: 22 January\u201316 March; lockdown: 17 March\u201310 May; post-lockdown: 11 May\u20134 July). We compared the overall rates of Caesarean delivery (CD), pre-labor CD, labor induction, operative vaginal delivery, severe postpartum hemorrhage (\u22651 L), severe perineal tear, maternal transfusion, and neonatal mortality and morbidity (1- and 5-min Apgar scores &lt; 7), hypoxia and anoxia (umbilical arterial pH &lt; 7.20 or &lt;7.10, respectively), and admission to a neonatal intensive care unit before discharge. Adjusted odds ratios were estimated using logistic regression, controlling for region of birth, maternal age category, multiparity, multiple pregnancies, diabetes, and hypertensive disorders. Results: The study sample consisted of 11,929 women who delivered consecutively at one of the six maternity units studied (4093 pre-lockdown, 3829 during lockdown, and 4007 post-lockdown) and their 12,179 neonates (4169 pre-lockdown, 3905 during lockdown, and 4105 post-lockdown). The maternal and obstetric characteristics of the women delivering during the lockdown period were alike those delivering pre- and post-lockdown on maternal age, parity, body mass index, rate of complication by hypertensive disorders or insulin-treated diabetes, and gestational age at delivery. Overall CD rates were similar during the three periods (23.6%, 24.8%, and 24.3% pre-lockdown, lockdown, and post-lockdown, respectively) and no outcome differed significantly during lockdown compared to pre- and post-lockdown. These findings were consistent across maternity units. Conclusion: The maternal and perinatal outcomes are reassuring regarding the performance of the health-care system during the COVID-19 lockdown studied. Such information is crucial, because additional COVID-19-related lockdowns might still be needed. They are also instructive regarding potential future pandemics.<\/jats:p>","DOI":"10.3390\/jcm11030756","type":"journal-article","created":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T01:46:08Z","timestamp":1643593568000},"page":"756","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Impact of COVID-19-Related Lockdown on Delivery and Perinatal Outcomes: A Retrospective Cohort Study"],"prefix":"10.3390","volume":"11","author":[{"given":"Thibaud","family":"Quibel","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Poissy-Saint Germain Hospital, 78300 Poissy, France"},{"name":"UVSQ, Inserm, Team U1018, Clinical Epidemiology, Centre de Recherche en \u00c9pid\u00e9-miologie et Sant\u00e9 des Populations (CESP), Paris Saclay University, 78180 Montigny-le-Bretonneux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Winer","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department, Centre Hospitalier Universitaire de Nantes, 44035 Nantes, France"},{"name":"UMR PhAN 1280 NUN INRAE F-44000 University Nantes, 44035 Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Bussi\u00e8res","sequence":"additional","affiliation":[{"name":"Obstetrics, and Fetal Medicine and Surgery Department, H\u00f4pital Necker-Enfants Maladies, AP-HP, 75007 Paris, France"},{"name":"EHU 7328 PACT, Universit\u00e9 de Paris, 75006 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Vayssi\u00e8re","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Paule de Viguier Hospital, CHU Toulouse, 31059 Toulouse, France"},{"name":"UMR1295 CERPOP (Centre for Epidemiology and Population Health Research), Team SPHERE (Study of Perinatal, Paedriatric and Adolescent Health: Epidemiological Research and Evaluation), Toulouse III University, 31062 Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Deruelle","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University Hospital of Strasbourg, Avenue Moliere, 67000 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manon","family":"Defrance","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Poissy-Saint Germain Hospital, 78300 Poissy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Rozenberg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Poissy-Saint Germain Hospital, 78300 Poissy, France"},{"name":"UVSQ, Inserm, Team U1018, Clinical Epidemiology, Centre de Recherche en \u00c9pid\u00e9-miologie et Sant\u00e9 des Populations (CESP), Paris Saclay University, 78180 Montigny-le-Bretonneux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Bouyer","sequence":"additional","affiliation":[{"name":"UVSQ, Inserm, Team U1018, Clinical Epidemiology, Centre de Recherche en \u00c9pid\u00e9-miologie et Sant\u00e9 des Populations (CESP), Paris Saclay University, 78180 Montigny-le-Bretonneux, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ninon","family":"Dupuis","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Paule de Viguier Hospital, CHU Toulouse, 31059 Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Renaudin","sequence":"additional","affiliation":[{"name":"Obstetrics, and Fetal Medicine and Surgery Department, H\u00f4pital Necker-Enfants Maladies, AP-HP, 75007 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Dugave","sequence":"additional","affiliation":[{"name":"CHU Lille, Department of Obstetrics, 59000 Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Banaszkiewicz","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department, Centre Hospitalier Universitaire de Nantes, 44035 Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2105-9784","authenticated-orcid":false,"given":"Charles","family":"Garabedian","sequence":"additional","affiliation":[{"name":"CHU Lille, Department of Obstetrics, 59000 Lille, France"},{"name":"University Lille, ULR 2694 METRICS, 59000 Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Ville","sequence":"additional","affiliation":[{"name":"Obstetrics, and Fetal Medicine and Surgery Department, H\u00f4pital Necker-Enfants Maladies, AP-HP, 75007 Paris, France"},{"name":"EHU 7328 PACT, Universit\u00e9 de Paris, 75006 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,30]]},"reference":[{"key":"ref_1","unstructured":"(2020, March 12). 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