{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T08:46:19Z","timestamp":1781081179613,"version":"3.54.1"},"reference-count":73,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T00:00:00Z","timestamp":1644537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Since the emergence of SARS-CoV-2, several studies have been published describing neuromuscular manifestations of the disease, as well as management of pre-existing pediatric neuromuscular disorders during the COVID-19 pandemic. These disorders include muscular dystrophies, myasthenic syndromes, peripheral nerve disorders, and spinal muscular atrophy. Such patients are a vulnerable population due to frequent complications such as scoliosis, cardiomyopathy, and restrictive lung disease that put them at risk of severe complications of COVID-19. In this review, neuromuscular manifestations of COVID-19 in children and the management of pre-existing pediatric neuromuscular disorders during the COVID-19 pandemic are discussed. We also review strategies to alleviate pandemic-associated disruptions in clinical care and research, including the emerging role of telemedicine and telerehabilitation to address the continued special needs of these patients.<\/jats:p>","DOI":"10.3390\/jcm11040934","type":"journal-article","created":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T05:14:43Z","timestamp":1644556483000},"page":"934","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A Comprehensive Review of Neuromuscular Manifestations of COVID-19 and Management of Pre-Existing Neuromuscular Disorders in Children"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6052-7141","authenticated-orcid":false,"given":"Daniel J.","family":"Goetschius","sequence":"first","affiliation":[{"name":"Penn State College of Medicine Medical Scientist Training Program, Hershey, PA 17033, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6935-390X","authenticated-orcid":false,"given":"Yunsung","family":"Kim","sequence":"additional","affiliation":[{"name":"Penn State College of Medicine Medical Scientist Training Program, Hershey, PA 17033, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4949-1395","authenticated-orcid":false,"given":"Ashutosh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Neurology, Penn State Health Children\u2019s Hospital, Penn State College of Medicine, Hershey, PA 17033, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1472-2528","authenticated-orcid":false,"given":"Dustin","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Texas Rio Grande Valley, Edinburg, TX 78539, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Naik","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Neurology, Penn State Health Children\u2019s Hospital, Penn State College of Medicine, Hershey, PA 17033, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,11]]},"reference":[{"key":"ref_1","first-page":"57","article-title":"Estimating the Impact of COVID-19 Pandemic on Services Provided by Italian Neuromuscular Centers: An Italian Association of Myology Survey of the Acute Phase","volume":"39","author":"Mauri","year":"2020","journal-title":"Acta Myol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/mus.26902","article-title":"The Care of Patients with Duchenne, Becker, and Other Muscular Dystrophies in the COVID-19 Pandemic","volume":"62","author":"Veerapandiyan","year":"2020","journal-title":"Muscle Nerve"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/mus.26903","article-title":"Spinal Muscular Atrophy Care in the COVID-19 Pandemic Era","volume":"62","author":"Veerapandiyan","year":"2020","journal-title":"Muscle Nerve"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.3389\/fgene.2021.735538","article-title":"Remote Delivery of Motor Function Assessment and Training for Clinical Trials in Neuromuscular Disease: A Response to the COVID-19 Global Pandemic","volume":"12","author":"James","year":"2021","journal-title":"Front. 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