{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:50:22Z","timestamp":1787028622607,"version":"build-2736575974"},"reference-count":38,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T00:00:00Z","timestamp":1646611200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"RED INVESTIGACI\u00d3N RENAL","award":["REDINREN, RD16\/0009\/0030"],"award-info":[{"award-number":["REDINREN, RD16\/0009\/0030"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background and objectives: Kidney biopsy (KB) is the \u201cgold standard\u201d for the diagnosis of nephropathies and it is a diagnostic tool that presents a low rate of complications. Nowadays, biobank collections of renal tissue of patients with proven renal pathology are essential for research in nephrology. To provide enough tissue for the biobank collection, it is usually needed to obtain an extra kidney core at the time of kidney biopsy. The objective of our study is to evaluate the complications after KB and to analyze whether obtaining an extra core increases the risk of complications. Material and methods: Prospective observational study of KBs performed at Vall d\u2019Hebron Hospital between 2019 and 2020. All patients who accepted to participate to our research biobank of native kidney biopsies were included to the study. Clinical and laboratory data were reviewed and we studied risk factors associated with complications. Results: A total of 221 patients were included, mean age 56.6 (\u00b116.8) years, 130 (58.8%) were men, creatinine was 2.24 (\u00b11.94) mg\/dL, proteinuria 1.56 (0.506\u20133.590) g\/24 h, hemoglobin 12.03 (\u00b12.3) g\/dL, INR 0.99 (\u00b10.1), and prothrombin time (PT) 11.86 (\u00b11.2) s. A total of 38 patients (17.2%) presented complications associated with the procedure: 13.1% were minor complications, 11.3% (n = 25) required blood transfusion, 1.4% (n = 3) had severe hematomas, 2.3% (n = 5) required embolization, and 0.5% (n = 1) presented arterio-venous fistula. An increased risk for complication was independently associated with obtaining a single kidney core (vs. 2 and 3 cores) (p = 0.021). Conclusions: KB is an invasive and safe procedure with a low percentage of complications. Obtaining an extra kidney core for research does not increase the risk of complications during the intervention, which remains low in concordance with previously published reports.<\/jats:p>","DOI":"10.3390\/jcm11051459","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T10:21:16Z","timestamp":1646648476000},"page":"1459","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Safety of Obtaining an Extra Biobank Kidney Biopsy Core"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3611-4830","authenticated-orcid":false,"given":"Sheila","family":"Bermejo","sequence":"first","affiliation":[{"name":"Nephrology Department, Hospital de Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Garc\u00eda-Carro","sequence":"additional","affiliation":[{"name":"Nephrology Department, Hospital Cl\u00ednico San Carlos, 28940 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Mast","sequence":"additional","affiliation":[{"name":"Radiology Department, Hospital de Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1926-0147","authenticated-orcid":false,"given":"Ander","family":"Vergara","sequence":"additional","affiliation":[{"name":"Nephrology Department, Hospital de Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4223-6834","authenticated-orcid":false,"given":"Irene","family":"Agraz","sequence":"additional","affiliation":[{"name":"Nephrology Department, Hospital de Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Le\u00f3n","sequence":"additional","affiliation":[{"name":"Nephrology Department, Hospital de Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Bolufer","sequence":"additional","affiliation":[{"name":"Nephrology Department, Hospital de Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria-Alejandra","family":"Gabaldon","sequence":"additional","affiliation":[{"name":"Pathology Department, Hospital de Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2054-653X","authenticated-orcid":false,"given":"Daniel","family":"Ser\u00f3n","sequence":"additional","affiliation":[{"name":"Nephrology Department, Hospital de Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oriol","family":"Bestard","sequence":"additional","affiliation":[{"name":"Nephrology Department, Hospital de Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3621-0766","authenticated-orcid":false,"given":"Maria Jose","family":"Soler","sequence":"additional","affiliation":[{"name":"Nephrology Department, Hospital de Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1053\/j.ajkd.2018.10.011","article-title":"Update on the Native Kidney Biopsy: Core Curriculum 2019","volume":"73","author":"Luciano","year":"2019","journal-title":"Am. 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