{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T11:26:16Z","timestamp":1763810776317,"version":"build-2065373602"},"reference-count":83,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T00:00:00Z","timestamp":1646784000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Living donor kidney transplantation is a widely performed medical procedure. Living kidney donation requires an in-depth health assessment of candidates. The potential living kidney donor must remain healthy after kidney removal. A consequence of donation can be a decrease in glomerular filtration rate (GFR), and donors can become at risk of developing chronic kidney disease (CKD). We present a rationale for potential living kidney donor withdrawal due to Paget\u2019s disease of bone (PDB) based on a literature review. The treatment for PDB includes the use of, for example, non-steroidal anti-inflammatory drugs (NSAIDs), which can lead to acute kidney injury (AKI) as well as CKD, or bisphosphonates, which are not recommended for patients with decreased GFR.<\/jats:p>","DOI":"10.3390\/jcm11061485","type":"journal-article","created":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T01:53:54Z","timestamp":1646790834000},"page":"1485","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Is a Patient with Paget\u2019s Disease of Bone Suitable for Living Kidney Donation?\u2014Decision-Making in Lack of Clinical Evidence"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1235-3551","authenticated-orcid":false,"given":"Pawe\u0142","family":"Pozna\u0144ski","sequence":"first","affiliation":[{"name":"Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Lepiesza","sequence":"additional","affiliation":[{"name":"Department of Vascular, General and Transplantation Surgery, Jan Mikulicz-Radecki University Clinical Hospital, Borowska 213, 50-556 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7053-142X","authenticated-orcid":false,"given":"Diana","family":"J\u0119drzejuk","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Isotope Therapy, Wroclaw Medical University, Wybrzeze L. Pasteura 4, 50-367 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oktawia","family":"Mazanowska","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2360-6596","authenticated-orcid":false,"given":"Marek","family":"Bolanowski","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Isotope Therapy, Wroclaw Medical University, Wybrzeze L. Pasteura 4, 50-367 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2632-2409","authenticated-orcid":false,"given":"Magdalena","family":"Krajewska","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2400-9328","authenticated-orcid":false,"given":"Dorota","family":"Kami\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e307","DOI":"10.1097\/TP.0000000000002253","article-title":"British Transplantation Society\/Renal Association UK Guidelines for Living Donor Kidney Transplantation 2018: Summary of Updated Guidance","volume":"102","author":"Andrews","year":"2018","journal-title":"Transplantation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1097\/TP.0000000000001769","article-title":"KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors","volume":"101","author":"Lentine","year":"2017","journal-title":"Transplantation"},{"key":"ref_3","unstructured":"World Health Organization (WHO) (2010). 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