{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:48:38Z","timestamp":1790779718661,"version":"4.1.0"},"reference-count":111,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T00:00:00Z","timestamp":1647475200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008546","name":"Diabetesf\u00f6rbundet","doi-asserted-by":"publisher","award":["DIA2020-492"],"award-info":[{"award-number":["DIA2020-492"]}],"id":[{"id":"10.13039\/501100008546","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"publisher","award":["2021-01942"],"award-info":[{"award-number":["2021-01942"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Regional Agreement on Medical Training and Clinical Research (ALF) between Region Sk\u00e5ne and Lund University","award":["not applicable"],"award-info":[{"award-number":["not applicable"]}]},{"name":"Elly Olsson's foundation","award":["not applicable"],"award-info":[{"award-number":["not applicable"]}]},{"name":"Gorthonstiftelsen","award":["not applicable"],"award-info":[{"award-number":["not applicable"]}]},{"name":"Almroth Foundation","award":["not applicable"],"award-info":[{"award-number":["not applicable"]}]},{"DOI":"10.13039\/501100006075","name":"Greta och Johan Kocks stiftelser","doi-asserted-by":"publisher","award":["not applicable"],"award-info":[{"award-number":["not applicable"]}],"id":[{"id":"10.13039\/501100006075","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006285","name":"Magnus Bergvalls Stiftelse","doi-asserted-by":"publisher","award":["2020-03612"],"award-info":[{"award-number":["2020-03612"]}],"id":[{"id":"10.13039\/501100006285","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Carpal tunnel syndrome (CTS) is the most common compression neuropathy in the general population and is frequently encountered among individuals with type 1 and 2 diabetes. The reason(s) why a peripheral nerve trunk in individuals with diabetes is more susceptible to nerve compression is still not completely clarified, but both biochemical and structural changes in the peripheral nerve are probably implicated. In particular, individuals with neuropathy, irrespective of aetiology, have a higher risk of peripheral nerve compression disorders, as reflected among individuals with diabetic neuropathy. Diagnosis of CTS in individuals with diabetes should be carefully evaluated; detailed case history, thorough clinical examination, and electrophysiological examination is recommended. Individuals with diabetes and CTS benefit from surgery to the same extent as otherwise healthy individuals with CTS. In the present review, we describe pathophysiological aspects of the nerve compression disorder CTS in relation to diabetes, current data contributing to the explanation of the increased risk for CTS in individuals with diabetes, as well as diagnostic methods, treatment options, and prognosis of CTS in diabetes.<\/jats:p>","DOI":"10.3390\/jcm11061674","type":"journal-article","created":{"date-parts":[[2022,3,20]],"date-time":"2022-03-20T21:30:14Z","timestamp":1647811814000},"page":"1674","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":72,"title":["Carpal Tunnel Syndrome and Diabetes\u2014A Comprehensive Review"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9925-3838","authenticated-orcid":false,"given":"Malin","family":"Zimmerman","sequence":"first","affiliation":[{"name":"Department of Hand Surgery, Sk\u00e5ne University Hospital, Lund University, 205 02 Malm\u00f6, Sweden"},{"name":"Department of Translational Medicine\u2014Hand Surgery, Lund University, 205 02 Malm\u00f6, Sweden"},{"name":"Department of Orthopaedic Surgery, Helsingborg Hospital, 251 87 Helsingborg, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Gotts\u00e4ter","sequence":"additional","affiliation":[{"name":"Department of Medicine, Sk\u00e5ne University Hospital, 205 02 Malm\u00f6, Sweden"},{"name":"Department of Clinical Sciences Malm\u00f6, Lund University, 205 02 Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1334-3099","authenticated-orcid":false,"given":"Lars B.","family":"Dahlin","sequence":"additional","affiliation":[{"name":"Department of Hand Surgery, Sk\u00e5ne University Hospital, Lund University, 205 02 Malm\u00f6, Sweden"},{"name":"Department of Translational Medicine\u2014Hand Surgery, Lund University, 205 02 Malm\u00f6, Sweden"},{"name":"Department of Biomedical and Clinical Sciences, Link\u00f6ping University, 581 83 Link\u00f6ping, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1136\/jnnp.2005.066696","article-title":"Incidence of common compressive neuropathies in primary care","volume":"77","author":"Latinovic","year":"2006","journal-title":"J. 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