{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T21:04:56Z","timestamp":1778619896583,"version":"3.51.4"},"reference-count":39,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T00:00:00Z","timestamp":1648425600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Alterations derived from lymphedema in the upper-limb secondary to breast cancer-related lymphedema (BCRL) decrease the health-related quality of life (HRQoL), but there is limited evidence of the impact of the different interventions on it. The aim of this research was to compare the effect of conventional treatment with another treatment based on Activity-Oriented Antiedema Proprioceptive Therapy (TAPA) on HRQoL in women diagnosed with BCRL. Methods: A prospective clinical study was designed with two parallel arms. The study population consisted of women diagnosed with BCRL in stage I and II, belonging to different institutions in C\u00f3rdoba and Aragon, Spain. Sociodemographic and HRQoL-related variables, pain, tightness, heaviness and functionality were obtained before and after treatments. Results: 51 women participated in the study, 25 received the conventional treatment and 26 the TAPA, with a mean age of 59.24 \u00b1 9.55 years. HRQoL was significantly related to upper-limb function and pain on the participants\u2019 affected side. In addition, covariance analysis (ANCOVA) showed that the TAPA treatment interfered less in the performance of activities of daily life and produced significant improvements in the social dimension of HRQoL. Conclusions: the non-use of compressive elements in the rehabilitative treatment of the BCRL that is proposed with TAPA improves aspects such as self-image and participation in social and recreational activities.<\/jats:p>","DOI":"10.3390\/jcm11071884","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T21:44:52Z","timestamp":1648590292000},"page":"1884","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Impact of Activity-Oriented Propioceptive Antiedema Therapy on the Health-Related Quality of Life of Women with Upper-Limb Lymphedema Secondary to Breast Cancer\u2014A Randomized Clinical Trial"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5680-759X","authenticated-orcid":false,"given":"Mar\u00eda","family":"Mu\u00f1oz-Alcaraz","sequence":"first","affiliation":[{"name":"Inter-Level Clinical Management Unit of Physical Medicine and Rehabilitation, Reina Sof\u00eda University Hospital\u2014C\u00f3rdoba and Guadalquivir Health District, Andalusia Health Service, 14004 C\u00f3rdoba, Spain"},{"name":"Maimonides Institute for Biomedical Research of C\u00f3rdoba, Reina Sof\u00eda University Hospital, University of C\u00f3rdoba, 14011 C\u00f3rdoba, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8784-4905","authenticated-orcid":false,"given":"Luis","family":"P\u00e9rula-de Torres","sequence":"additional","affiliation":[{"name":"Maimonides Institute for Biomedical Research of C\u00f3rdoba, Reina Sof\u00eda University Hospital, University of C\u00f3rdoba, 14011 C\u00f3rdoba, Spain"},{"name":"Multiprofessional Teaching Unit for Family and Community Care of the C\u00f3rdoba and Guadalquivir Health District, 14011 C\u00f3rdoba, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2435-5397","authenticated-orcid":false,"given":"Antonio","family":"Jim\u00e9nez-V\u00edlchez","sequence":"additional","affiliation":[{"name":"Valle de los Pedroches Hospital, Andalusia Health Service, 14400 Pozoblanco, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Rodr\u00edguez-Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Burgos, 09001 Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Olmo-Carmona","sequence":"additional","affiliation":[{"name":"Inter-Level Clinical Management Unit of Physical Medicine and Rehabilitation, Reina Sof\u00eda University Hospital\u2014C\u00f3rdoba and Guadalquivir Health District, Andalusia Health Service, 14004 C\u00f3rdoba, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Mu\u00f1oz-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Inter-Level Clinical Management Unit of Physical Medicine and Rehabilitation, Reina Sof\u00eda University Hospital\u2014C\u00f3rdoba and Guadalquivir Health District, Andalusia Health Service, 14004 C\u00f3rdoba, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Presentaci\u00f3n","family":"Jorge-Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Inter-Level Clinical Management Unit of Physical Medicine and Rehabilitation, Reina Sof\u00eda University Hospital\u2014C\u00f3rdoba and Guadalquivir Health District, Andalusia Health Service, 14004 C\u00f3rdoba, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas","family":"Serrano-Merino","sequence":"additional","affiliation":[{"name":"Maimonides Institute for Biomedical Research of C\u00f3rdoba, Reina Sof\u00eda University Hospital, University of C\u00f3rdoba, 14011 C\u00f3rdoba, Spain"},{"name":"Multiprofessional Teaching Unit for Family and Community Care of the C\u00f3rdoba and Guadalquivir Health District, 14011 C\u00f3rdoba, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5054-3845","authenticated-orcid":false,"given":"Esperanza","family":"Romero-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Maimonides Institute for Biomedical Research of C\u00f3rdoba, Reina Sof\u00eda University Hospital, University of C\u00f3rdoba, 14011 C\u00f3rdoba, Spain"},{"name":"Multiprofessional Teaching Unit for Family and Community Care of the C\u00f3rdoba and Guadalquivir Health District, 14011 C\u00f3rdoba, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena","family":"Rodr\u00edguez-Elena","sequence":"additional","affiliation":[{"name":"San Jose Health Center, Aragonese Health Service, 50013 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2770-6399","authenticated-orcid":false,"given":"Raquel","family":"Refusta-Ainaga","sequence":"additional","affiliation":[{"name":"San Jose Health Center, Aragonese Health Service, 50013 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7803-4820","authenticated-orcid":false,"given":"Mar\u00eda","family":"Lahoz-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"San Jose Health Center, Aragonese Health Service, 50013 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bel\u00e9n","family":"Mir\u00f3-Palacios","sequence":"additional","affiliation":[{"name":"Association of People with Lymphedema in Aragon (ADPLA), 50007 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayra","family":"Medrano-Cid","sequence":"additional","affiliation":[{"name":"Lozano Blesa University Clinical Hospital, Aragonese Health Service, 50009 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5494-6550","authenticated-orcid":false,"given":"Rosa","family":"Magall\u00f3n-Botaya","sequence":"additional","affiliation":[{"name":"Institute for Health Research Aragon (IIS Aragon), University of Zaragoza, 50009 Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4255-7355","authenticated-orcid":false,"given":"Mirian","family":"Santamar\u00eda-Pel\u00e1ez","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Burgos, 09001 Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"M\u00ednguez-M\u00ednguez","sequence":"additional","affiliation":[{"name":"Department of Educational Sciences, University of Burgos, 09001 Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7298-9060","authenticated-orcid":false,"given":"Jer\u00f3nimo","family":"Gonz\u00e1lez-Bernal","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Burgos, 09001 Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1245\/s10434-021-10645-3","article-title":"Diagnostic Criteria for Breast Cancer-Related Lymphedema of the Upper Extremity: The Need for Universal Agreement","volume":"29","author":"Kassamani","year":"2021","journal-title":"Ann. 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