{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:28:10Z","timestamp":1785353290975,"version":"3.55.0"},"reference-count":18,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T00:00:00Z","timestamp":1651104000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Most interventionalists use the Amplatzer Duct Occluder (ADO) or the Nit-Occlud\u00ae Coils (NOC) to close patent ductus arteriosus (PDA). Data regarding the success and effect of NOCs in the occlusion of large PDAs are insufficient. We aimed to investigate whether the PDA occlusion of large PDAs using NOC is safe and efficient for all ages. This was a retrospective study involving 361 pediatric and adult patients who underwent the transcatheter closure of PDA using NOC over the past 21 years for all PDA sizes and ages. The sizes of PDA were classified as small, moderate, and large. A comparison of the aortic pressure before and after PDA occlusion using NOC showed significant differences in terms of systolic and pulse pressures for all age groups (p &lt; 0.05). The rate of the residual shunts of NOC was 2%, while the rate of complete occlusions of NOC was 98% at 12 months after occlusion regardless of the shape of PDA. The complication rate with PDA occlusion using NOC was 5%. PDA occlusion using NOC is as effective and safe as ADO for the occlusion of PDA of all sizes. Therefore, PDA occlusion using NOC can be a safe and feasible procedure to close various sizes and types of PDA without complications.<\/jats:p>","DOI":"10.3390\/jcm11092469","type":"journal-article","created":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T22:20:06Z","timestamp":1651184406000},"page":"2469","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Safety and Efficacy of the Nit-Occlud\u00ae Coil for Percutaneous Closure of Various Sizes of PDA"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1337-563X","authenticated-orcid":false,"given":"Seyong","family":"Jung","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology, College of Medicine, Yonsei University, Seoul 03722, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8258-3497","authenticated-orcid":false,"given":"Jaehee","family":"Seol","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Yonsei University Wonju College of Medicine, Wonju 26426, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaeyoung","family":"Choi","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, College of Medicine, Yonsei University, Seoul 03722, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keesoo","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, College of Medicine, Korea University, Seoul 02841, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,28]]},"reference":[{"key":"ref_1","first-page":"37","article-title":"Comparison of cost-effectiveness and postoperative outcome of device closure and open surgery closure techniques for treatment of patent ductus arteriosus","volume":"10","author":"Ahmadi","year":"2014","journal-title":"ARYA Atheroscler."},{"key":"ref_2","first-page":"259","article-title":"Closure of persistent ductus arteriosus without thoracotomy","volume":"12","author":"Porstmann","year":"1967","journal-title":"Ger. 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