{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:37:45Z","timestamp":1790645865210,"version":"4.1.0"},"reference-count":202,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T00:00:00Z","timestamp":1651104000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01EY030851"],"award-info":[{"award-number":["R01EY030851"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NSF DMS (1853222\/2021192)"],"award-info":[{"award-number":["NSF DMS (1853222\/2021192)"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NYEE Foundation grant"],"award-info":[{"award-number":["NYEE Foundation grant"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["Challenge Grant award"],"award-info":[{"award-number":["Challenge Grant award"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["R01EY030851"],"award-info":[{"award-number":["R01EY030851"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["NSF DMS (1853222\/2021192)"],"award-info":[{"award-number":["NSF DMS (1853222\/2021192)"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["NYEE Foundation grant"],"award-info":[{"award-number":["NYEE Foundation grant"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["Challenge Grant award"],"award-info":[{"award-number":["Challenge Grant award"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NYEE Foundation","award":["R01EY030851"],"award-info":[{"award-number":["R01EY030851"]}]},{"name":"NYEE Foundation","award":["NSF DMS (1853222\/2021192)"],"award-info":[{"award-number":["NSF DMS (1853222\/2021192)"]}]},{"name":"NYEE Foundation","award":["NYEE Foundation grant"],"award-info":[{"award-number":["NYEE Foundation grant"]}]},{"name":"NYEE Foundation","award":["Challenge Grant award"],"award-info":[{"award-number":["Challenge Grant award"]}]},{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","award":["R01EY030851"],"award-info":[{"award-number":["R01EY030851"]}],"id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","award":["NSF DMS (1853222\/2021192)"],"award-info":[{"award-number":["NSF DMS (1853222\/2021192)"]}],"id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","award":["NYEE Foundation grant"],"award-info":[{"award-number":["NYEE Foundation grant"]}],"id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","award":["Challenge Grant award"],"award-info":[{"award-number":["Challenge Grant award"]}],"id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Primary open-angle glaucoma (POAG) is an optic neuropathy characterized by irreversible retinal ganglion cell damage and visual field loss. The global POAG prevalence is estimated to be 3.05%, and near term is expected to significantly rise, especially within aging Asian populations. Primary angle-closure glaucoma disproportionately affects Asians, with up to four times greater prevalence of normal-tension glaucoma reported compared with high-tension glaucoma. Estimates for overall POAG prevalence in Asian populations vary, with Chinese and Indian populations representing the majority of future cases. Structural characteristics associated with glaucoma progression including the optic nerve head, retina, and cornea are distinct in Asians, serving as intermediates between African and European descent populations. Patterns in IOP suggest some similarities between races, with a significant inverse relationship between age and IOP only in Asian populations. Genetic differences have been suggested to play a role in these differences, however, a clear genetic pattern is yet to be established. POAG pathogenesis differs between Asians and other ethnicities, and it may differ within the broad classification of the Asian race. Greater awareness and further research are needed to improve treatment plans and outcomes for the increasingly high prevalence of normal tension glaucoma within aging Asian populations.<\/jats:p>","DOI":"10.3390\/jcm11092486","type":"journal-article","created":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T22:20:06Z","timestamp":1651184406000},"page":"2486","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Asian Race and Primary Open-Angle Glaucoma: Where Do We Stand?"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2247-6942","authenticated-orcid":false,"given":"Aditya","family":"Belamkar","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alon","family":"Harris","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Oddone","sequence":"additional","affiliation":[{"name":"IRCCS-Fondazione Bietti, 00198 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Verticchio Vercellin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Fabczak-Kubicka","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"},{"name":"New York Eye & Ear Infirmary of Mount Sinai, New York, NY 10003, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brent","family":"Siesky","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040: A systematic review and meta-analysis","volume":"121","author":"Tham","year":"2014","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1001\/archopht.120.6.701","article-title":"The Ocular Hypertension Treatment Study: A randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma","volume":"120","author":"Kass","year":"2002","journal-title":"Arch. Ophthalmol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1001\/archopht.121.1.48","article-title":"Factors for Glaucoma Progression and the Effect of Treatment: The early manifest glaucoma trial","volume":"121","author":"Leske","year":"2003","journal-title":"Arch. Ophthalmol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br. J. Ophthalmol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"624179","DOI":"10.3389\/fmed.2020.624179","article-title":"Prevalence of Primary Angle Closure Glaucoma in the Last 20 Years: A Meta-Analysis and Systematic Review","volume":"7","author":"Zhang","year":"2021","journal-title":"Front. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1016\/S0140-6736(17)31469-1","article-title":"Glaucoma","volume":"390","author":"Jonas","year":"2017","journal-title":"Lancet"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"16067","DOI":"10.1038\/nrdp.2016.67","article-title":"Primary open-angle glaucoma","volume":"2","author":"Weinreb","year":"2016","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/sj.eye.6701797","article-title":"Angle-closure glaucoma in East Asian and European people. Different diseases?","volume":"20","author":"He","year":"2006","journal-title":"Eye"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/j.ophtha.2010.10.024","article-title":"Differences in Rates of Glaucoma among Asian Americans and Other Racial Groups, and among Various Asian Ethnic Groups","volume":"118","author":"Stein","year":"2011","journal-title":"Ophthalmology"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1001\/jamaophthalmol.2015.1110","article-title":"The Prevalence and Types of Glaucoma in an Urban Chinese Population: The Singapore Chinese Eye Study","volume":"133","author":"Baskaran","year":"2015","journal-title":"JAMA Ophthalmol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1136\/bjophthalmol-2014-306102","article-title":"Glaucoma in Asia: Regional prevalence variations and future projections","volume":"100","author":"Chan","year":"2016","journal-title":"Br. J. Ophthalmol."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Guo, B., Tan, Y., Nygaard, S., Carrillo, C., Nouansavanh, K.O., Souksamone, K., and Casson, R.J. (Br. J. Ophthalmol., 2021). Prevalence of glaucoma in the Lao People\u2019s Democratic Republic: The Vientiane Eye Study, Br. J. Ophthalmol., Online ahead of print.","DOI":"10.1136\/bjophthalmol-2020-317658"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.ajo.2018.10.017","article-title":"Prevalence of Normal-Tension Glaucoma in the Chinese Population: A Systematic Review and Meta-Analysis","volume":"199","author":"Zhao","year":"2018","journal-title":"Am. J. Ophthalmol."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"He, J., Zou, H., Lee, R.K., Tong, X., Tang, W., Zhang, Y., Zhao, R., and Ge, L. (2015). Prevalence and risk factors of primary open-angle glaucoma in a city of Eastern China: A population-based study in Pudong New District, Shanghai. BMC Ophthalmol., 15.","DOI":"10.1186\/s12886-015-0124-x"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1097\/IJG.0b013e318279b3e2","article-title":"Open-angle Glaucoma in Filipino and White Americans: A comparative study","volume":"23","author":"Sales","year":"2014","journal-title":"J. Glaucoma"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4103\/0301-4738.107191","article-title":"The British Asian Community Eye Study: Outline of results on the prevalence of eye disease in British Asians with origins from the Indian subcontinent","volume":"61","author":"Rauf","year":"2013","journal-title":"Indian J. Ophthalmol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"4621","DOI":"10.1167\/iovs.13-11950","article-title":"The Prevalence and Types of Glaucoma in an Urban Indian Population: The Singapore Indian Eye Study","volume":"54","author":"Narayanaswamy","year":"2013","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_18","first-page":"82","article-title":"Review of key findings from the Singapore Malay Eye Study (SiMES-1)","volume":"53","author":"Rosman","year":"2012","journal-title":"Singap. Med. J."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"8250","DOI":"10.1167\/iovs.11-7472","article-title":"Prevalence of Primary Open Angle Glaucoma in a Rural Adult Chinese Population: The Handan Eye Study","volume":"52","author":"Liang","year":"2011","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"3846","DOI":"10.1167\/iovs.08-1759","article-title":"The Prevalence and Types of Glaucoma in Malay People: The Singapore Malay Eye Study","volume":"49","author":"Shen","year":"2008","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2782","DOI":"10.1167\/iovs.06-0051","article-title":"Prevalence and Clinical Characteristics of Glaucoma in Adult Chinese: A Population-Based Study in Liwan District, Guangzhou","volume":"47","author":"He","year":"2006","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"4254","DOI":"10.1167\/iovs.06-0299","article-title":"Variations in Primary Open-Angle Glaucoma Prevalence by Age, Gender, and Race: A Bayesian Meta-Analysis","volume":"47","author":"Rudnicka","year":"2006","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.ogla.2020.09.004","article-title":"Six-Year Incidence and Risk Factors of Primary Glaucoma in the Singapore Indian Eye Study","volume":"4","author":"Koh","year":"2021","journal-title":"Ophthalmol. Glaucoma"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1001\/archophthalmol.2008.593","article-title":"The Characteristics of Glaucoma in Japanese Americans","volume":"127","author":"Pekmezci","year":"2009","journal-title":"Arch. Ophthalmol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1136\/bjophthalmol-2015-307223","article-title":"Global variations and time trends in the prevalence of primary open angle glaucoma (POAG): A systematic review and meta-analysis","volume":"100","author":"Kapetanakis","year":"2016","journal-title":"Br. J. Ophthalmol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1001\/jama.2020.21899","article-title":"Glaucoma in Adults\u2014Screening, Diagnosis, and Management: A Review","volume":"325","author":"Stein","year":"2021","journal-title":"JAMA"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"e039183","DOI":"10.1136\/bmjopen-2020-039183","article-title":"Natural history of glaucomatous optic neuropathy in highly myopic Chinese: Study protocol for a registry cohort study","volume":"10","author":"Song","year":"2020","journal-title":"BMJ Open"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/ceo.13008","article-title":"Social, health and ocular factors associated with primary open-angle glaucoma amongst Chinese Singaporeans","volume":"46","author":"Chiam","year":"2018","journal-title":"Clin. Exp. Ophthalmol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"726760","DOI":"10.1155\/2014\/726760","article-title":"Risk Factors for Glaucoma Suspicion in Healthy Young Asian and Caucasian Americans","volume":"2014","author":"Doss","year":"2014","journal-title":"J. Ophthalmol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1001\/archophthalmol.2010.125","article-title":"Refractive Error, Axial Dimensions, and Primary Open-Angle Glaucoma: The Singapore Malay Eye Study","volume":"128","author":"Perera","year":"2010","journal-title":"Arch. Ophthalmol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1016\/j.ophtha.2006.03.059","article-title":"Risk Factors for Open-Angle Glaucoma in a Japanese Population: The Tajimi Study","volume":"113","author":"Suzuki","year":"2006","journal-title":"Ophthalmology"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"19320","DOI":"10.1038\/srep19320","article-title":"Joint Effects of Intraocular Pressure and Myopia on Risk of Primary Open-Angle Glaucoma: The Singapore Epidemiology of Eye Diseases Study","volume":"6","author":"Tham","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1136\/bjophthalmol-2011-301224","article-title":"Frequency and associated factors of structural progression of open-angle glaucoma in the Beijing Eye Study: Table 1","volume":"96","author":"Wang","year":"2012","journal-title":"Br. J. Ophthalmol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1167\/iovs.17-23013","article-title":"Direct and Indirect Associations Between Diabetes and Intraocular Pressure: The Singapore Epidemiology of Eye Diseases Study","volume":"59","author":"Luo","year":"2018","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Bae, H.W., Lee, N., Lee, H.S., Hong, S., Seong, G.J., and Kim, C.Y. (2014). Systemic Hypertension as a Risk Factor for Open-Angle Glaucoma: A Meta-Analysis of Population-Based Studies. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0108226"},{"key":"ref_36","first-page":"297","article-title":"Obstructive sleep apnea\/hypopnea syndrome increases glaucoma risk: Evidence from a meta-analysis","volume":"8","author":"Wu","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00417-009-1183-6","article-title":"Reduced-serum vitamin C and increased uric acid levels in normal-tension glaucoma","volume":"248","author":"Yuki","year":"2010","journal-title":"Graefe\u2019s Arch. Clin. Exp. Ophthalmol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1017\/S1368980013003492","article-title":"Is vitamin D status associated with open-angle glaucoma? A cross-sectional study from South Korea","volume":"17","author":"Yoo","year":"2014","journal-title":"Public Health Nutr."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1001\/jamaophthalmol.2014.2876","article-title":"Association Between Serum Ferritin and Glaucoma in the South Korean Population","volume":"132","author":"Lin","year":"2014","journal-title":"JAMA Ophthalmol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s00417-009-1204-5","article-title":"Level of education associated with ophthalmic diseases. The Beijing Eye Study","volume":"248","author":"Xu","year":"2010","journal-title":"Graefe\u2019s Arch. Clin. Exp. Ophthalmol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1136\/bjo.2007.123273","article-title":"The morphology of the optic nerve head in the Singaporean Chinese population (the Tanjong Pagar study): Part 1\u2014Optic nerve head morphology","volume":"92","author":"Bourne","year":"2008","journal-title":"Br. J. Ophthalmol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1097\/IJG.0b013e3181996f05","article-title":"Optic Disk Size Variability Between African, Asian, White, Hispanic, and Filipino Americans Using Heidelberg Retinal Tomography","volume":"18","author":"Seider","year":"2009","journal-title":"J. Glaucoma"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1136\/bjo.2009.158279","article-title":"Ethnic differences in optic nerve head and retinal nerve fibre layer thickness parameters in children","volume":"94","author":"Samarawickrama","year":"2010","journal-title":"Br. J. Ophthalmol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1097\/IJG.0000000000000889","article-title":"Differences in Optic Nerve Head, Retinal Nerve Fiber Layer, and Ganglion Cell Complex Parameters Between Caucasian and Chinese Subjects","volume":"27","author":"Chansangpetch","year":"2018","journal-title":"J. Glaucoma"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.2147\/OPTH.S71136","article-title":"Optic disc topography in Malay patients with normal-tension glaucoma and primary open-angle glaucoma","volume":"8","author":"Shatriah","year":"2014","journal-title":"Clin. Ophthalmol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3126\/nepjoph.v4i1.5852","article-title":"Retinal nerve fiber layer thickness in Indian eyes with optical coherence tomography","volume":"4","author":"Malik","year":"2012","journal-title":"Nepal. J. Ophthalmol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1097\/IJG.0b013e31814b9817","article-title":"Retinal Nerve Fiber Layer Thickness in Normal, Ocular Hypertensive, and Glaucomatous Indian Eyes: An optical coherence tomography study","volume":"17","author":"Gyatsho","year":"2008","journal-title":"J. Glaucoma"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/j.ophtha.2020.01.055","article-title":"Profiles of Ganglion Cell-Inner Plexiform Layer Thickness in a Multi-Ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study","volume":"127","author":"Tham","year":"2020","journal-title":"Ophthalmology"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.ophtha.2018.11.031","article-title":"Retinal Nerve Fiber Layer Thickness in a Multiethnic Normal Asian Population: The Singapore Epidemiology of Eye Diseases Study","volume":"126","author":"Ho","year":"2019","journal-title":"Ophthalmology"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/IJG.0000000000001180","article-title":"Central Corneal Thickness Variances Among Different Asian Ethnicities in Glaucoma and Nonglaucoma Patients","volume":"28","author":"Badr","year":"2019","journal-title":"J. Glaucoma"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0002-9394(03)00424-0","article-title":"Intraocular pressure, Goldmann applanation tension, corneal thickness, and corneal curvature in Caucasians, Asians, Hispanics, and African Americans","volume":"136","author":"Shimmyo","year":"2003","journal-title":"Am. J. Ophthalmol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1001\/archopthalmol.2011.1576","article-title":"Effect of Race, Age, and Axial Length on Optic Nerve Head Parameters and Retinal Nerve Fiber Layer Thickness Measured by Cirrus HD-OCT","volume":"130","author":"Knight","year":"2012","journal-title":"Arch. Ophthalmol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1016\/j.ophtha.2004.06.013","article-title":"Central corneal thickness of Caucasians, Chinese, Hispanics, Filipinos, African Americans, and Japanese in a glaucoma clinic","volume":"111","author":"Aghaian","year":"2004","journal-title":"Ophthalmology"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1097\/IJG.0000000000000088","article-title":"The Impact of Central Corneal Thickness on the Risk for Glaucoma in a Large Multiethnic Population","volume":"23","author":"Wang","year":"2014","journal-title":"J. Glaucoma"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1016\/j.ophtha.2014.04.041","article-title":"Ethnic Differences of Intraocular Pressure and Central Corneal Thickness: The Singapore Epidemiology of Eye Diseases study","volume":"121","author":"Chua","year":"2014","journal-title":"Ophthalmology"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Pan, C.-W., Li, J., Zhong, H., Shen, W., Niu, Z., Yuan, Y., and Chen, Q. (2015). Ethnic Variations in Central Corneal Thickness in a Rural Population in China: The Yunnan Minority Eye Studies. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0135913"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1167\/iovs.10-6038","article-title":"Relationship of Central Corneal Thickness with Optic Disc Parameters: The Singapore Malay Eye Study","volume":"52","author":"Wu","year":"2011","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1097\/IJG.0b013e3181dde051","article-title":"Central Corneal Thickness and Anterior Scleral Thickness in Korean Patients with Open-angle Glaucoma: An anterior segment optical coherence tomography study","volume":"20","author":"Yoo","year":"2011","journal-title":"J. Glaucoma"},{"key":"ref_59","first-page":"50","article-title":"Central corneal thickness of normal-tension glaucoma and non-glaucoma populations in ethnic Chinese","volume":"27","author":"Chen","year":"2004","journal-title":"Chang. Gung Med. J."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.ajo.2008.10.013","article-title":"Central Corneal Thickness and its Associations with Ocular and Systemic Factors: The Singapore Malay Eye Study","volume":"147","author":"Su","year":"2009","journal-title":"Am. J. Ophthalmol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"6851","DOI":"10.1167\/iovs.12-10173","article-title":"Central Corneal Thickness in a Korean Population: The Namil Study","volume":"53","author":"Hwang","year":"2012","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"8407","DOI":"10.1167\/iovs.11-7927","article-title":"Central Corneal Thickness and Glaucoma in East Asian People","volume":"52","author":"Day","year":"2011","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"e186647","DOI":"10.1001\/jamanetworkopen.2018.6647","article-title":"Association of Diabetes with Central Corneal Thickness Among a Multiethnic Asian Population","volume":"2","author":"Luo","year":"2019","journal-title":"JAMA Netw. Open"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ophtha.2012.07.063","article-title":"Retinal Vascular Geometry and Glaucoma: The Singapore Malay Eye Study","volume":"120","author":"Wu","year":"2013","journal-title":"Ophthalmology"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"5397","DOI":"10.1167\/iovs.08-2142","article-title":"Evidence of Retinal Vascular Narrowing in Glaucomatous Eyes in an Asian Population","volume":"49","author":"Amerasinghe","year":"2008","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"7309","DOI":"10.1167\/iovs.13-12796","article-title":"Relationship between Retinal Vascular Geometry with Retinal Nerve Fiber Layer and Ganglion Cell-Inner Plexiform Layer in Nonglaucomatous Eyes","volume":"54","author":"Tham","year":"2013","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"3803","DOI":"10.1167\/iovs.15-18683","article-title":"Inter-Relationships Between Retinal Vascular Caliber, Retinal Nerve Fiber Layer Thickness, and Glaucoma: A Mediation Analysis Approach","volume":"57","author":"Tham","year":"2016","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1111\/j.1442-9071.2007.01627.x","article-title":"Retinal vessel diameter in normal and glaucomatous eyes: The Beijing eye study","volume":"35","author":"Wang","year":"2007","journal-title":"Clin. Exp. Ophthalmol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"4091","DOI":"10.1167\/iovs.09-3444","article-title":"Relationship of Retinal Vascular Caliber with Retinal Nerve Fiber Layer Thickness: The Singapore Malay Eye Study","volume":"50","author":"Zheng","year":"2009","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"3736","DOI":"10.1167\/iovs.09-5008","article-title":"Relationship of Retinal Vascular Tortuosity with the Neuroretinal Rim: The Singapore Malay Eye Study","volume":"51","author":"Koh","year":"2010","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"9585","DOI":"10.1038\/srep09585","article-title":"Retinal Vessels Change in Primary Angle-Closure Glaucoma: The Handan Eye Study","volume":"5","author":"Gao","year":"2015","journal-title":"Sci. Rep."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"e000032","DOI":"10.1136\/bmjophth-2016-000032","article-title":"Retinal vasculature in glaucoma: A review","volume":"1","author":"Chan","year":"2017","journal-title":"BMJ Open Ophthalmol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.ophtha.2004.08.015","article-title":"Retinal vessel diameter and open-angle glaucoma: The Blue Mountains Eye Study","volume":"112","author":"Mitchell","year":"2005","journal-title":"Ophthalmology"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.ajo.2003.10.020","article-title":"The relation of retinal microvascular characteristics to age-related eye disease: The Beaver Dam eye study","volume":"137","author":"Klein","year":"2004","journal-title":"Am. J. Ophthalmol."},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"Arnould, L., Guillemin, M., Seydou, A., Gabrielle, P.-H., Bourredjem, A., Kawasaki, R., Binquet, C., Bron, A.M., and Creuzot-Garcher, C. (2020). Association between the retinal vascular network and retinal nerve fiber layer in the elderly: The Montrachet study. PLoS ONE, 15.","DOI":"10.1371\/journal.pone.0241055"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"e1009","DOI":"10.1111\/aos.14448","article-title":"Diagnostic ability of spectral-domain optical coherence tomography peripapillary retinal nerve fiber layer thickness to discriminate glaucoma patients from controls in an elderly population (The MONTRACHET study)","volume":"98","author":"Arnould","year":"2020","journal-title":"Acta Ophthalmol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"e88","DOI":"10.1111\/aos.14192","article-title":"Retinal vessel phenotype in patients with primary open-angle glaucoma","volume":"98","author":"Chiquet","year":"2020","journal-title":"Acta Ophthalmol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1016\/j.ophtha.2018.03.026","article-title":"Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population","volume":"125","author":"Mauschitz","year":"2018","journal-title":"Ophthalmology"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"3650","DOI":"10.1167\/iovs.12-11126","article-title":"Racial Differences in Retinal Vessel Geometric Characteristics: A Multiethnic Study in Healthy Asians","volume":"54","author":"Li","year":"2013","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_80","doi-asserted-by":"crossref","unstructured":"Zhu, M.M., Choy, B.N.K., You, Q.S., Chan, J.C.H., Ng, A.L.K., Shih, K., Cheung, J.J.C., Wong, J.K.W., Shum, J., and Ni, M.Y. (2021). Optic disc and peripapillary vessel density measured with optical coherence tomography angiography and its associations in Chinese adults: A large population-based study. Br. J. Ophthalmol.","DOI":"10.1136\/bjophthalmol-2020-318199"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"6007","DOI":"10.1167\/iovs.14-14996","article-title":"Choroidal Thickness and Primary Open-Angle Glaucoma: A Cross-Sectional Study and Meta-Analysis","volume":"55","author":"Wang","year":"2014","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1111\/j.1442-9071.2011.02658.x","article-title":"Differences in iris structural measurements among American Caucasians, American Chinese and mainland Chinese","volume":"40","author":"Wang","year":"2012","journal-title":"Clin. Exp. Ophthalmol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"9404","DOI":"10.1167\/iovs.11-8470","article-title":"Differences in Baseline Dark and the Dark-to-Light Changes in Anterior Chamber Angle Parameters in Whites and Ethnic Chinese","volume":"52","author":"Wang","year":"2011","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1167\/iovs.07-1429","article-title":"Lamina Cribrosa and Peripapillary Sclera Histomorphometry in Normal and Advanced Glaucomatous Chinese Eyes with Various Axial Length","volume":"50","author":"Ren","year":"2009","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1136\/bjophthalmol-2020-315840","article-title":"Determinants of lamina cribrosa depth in healthy Asian eyes: The Singapore Epidemiology Eye Study","volume":"105","author":"Tun","year":"2021","journal-title":"Br. J. Ophthalmol."},{"key":"ref_86","first-page":"1845","article-title":"Differences in ocular biometrics and aqueous humour dynamics between Chinese and Caucasian adults","volume":"103","author":"Fan","year":"2019","journal-title":"Br. J. Ophthalmol."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1001\/jamaophthalmol.2013.7612","article-title":"Heritabilities of Intraocular Pressure in the Population of Korea: The Korean National Health and Nutrition Examination Survey 2008\u20132009","volume":"132","author":"Kim","year":"2014","journal-title":"JAMA Ophthalmol."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.ophtha.2011.09.016","article-title":"Epidemiologic Characteristics of Intraocular Pressure in the Korean and Mongolian Populations: The Healthy Twin and the GENDISCAN Study","volume":"119","author":"Lee","year":"2012","journal-title":"Ophthalmology"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"278","DOI":"10.3109\/09286586.2012.708084","article-title":"Intraocular Pressure and its Relationship to Ocular and Systemic Factors in a Healthy Chinese Rural Population: The Handan Eye Study","volume":"19","author":"Zhou","year":"2012","journal-title":"Ophthalmic Epidemiol."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.ajo.2011.03.005","article-title":"Intraocular Pressure, Central Corneal Thickness, and Glaucoma in Chinese Adults: The Liwan Eye Study","volume":"152","author":"Wang","year":"2011","journal-title":"Am. J. Ophthalmol."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1097\/IJG.0b013e3181f7af9b","article-title":"Intraocular Pressure and Associated Factors: The central India eye and medical study","volume":"20","author":"Jonas","year":"2011","journal-title":"J. Glaucoma"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1136\/bjo.2007.128819","article-title":"Ocular and systemic factors related to intraocular pressure in Japanese adults: The Tajimi study","volume":"92","author":"Kawase","year":"2008","journal-title":"Br. J. Ophthalmol."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"3885","DOI":"10.1167\/iovs.03-0012","article-title":"Determinants of intraocular pressure and its association with glaucomatous optic neuropathy in Chinese Singaporeans: The Tanjong Pagar Study","volume":"44","author":"Foster","year":"2003","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/eye.2014.43","article-title":"High intraocular pressure is associated with cardiometabolic risk factors in South Korean men: Korean National Health and Nutrition Examination Survey, 2008\u20132010","volume":"28","author":"Kim","year":"2014","journal-title":"Eye"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.ophtha.2015.01.024","article-title":"Aggregate Effects of Intraocular Pressure and Cup-to-Disc Ratio Genetic Variants on Glaucoma in a Multiethnic Asian Population","volume":"122","author":"Tham","year":"2015","journal-title":"Ophthalmology"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/eye.2015.11","article-title":"Longitudinal analysis of age-related changes in intraocular pressure in South Korea","volume":"29","author":"Baek","year":"2015","journal-title":"Eye"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1136\/bjophthalmol-2018-311897","article-title":"Inter-relationship between ageing, body mass index, diabetes, systemic blood pressure and intraocular pressure in Asians: 6-year longitudinal study","volume":"103","author":"Chua","year":"2019","journal-title":"Br. J. Ophthalmol."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1076\/ceyr.24.2.81.8161","article-title":"The relationship between age and intraocular pressure in a Japanese population: The influence of central corneal thickness","volume":"24","author":"Nomura","year":"2002","journal-title":"Curr. Eye Res."},{"key":"ref_99","first-page":"2224","article-title":"Intraocular pressure in an American community. The Beaver Dam Eye Study","volume":"33","author":"Klein","year":"1992","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1001\/archopht.1997.01100160742012","article-title":"Associations with Intraocular Pressure in the Barbados Eye Study","volume":"115","author":"Wu","year":"1997","journal-title":"Arch. Ophthalmol."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"e336","DOI":"10.1111\/aos.12354","article-title":"Vascular considerations in glaucoma patients of African and European descent","volume":"92","author":"Huck","year":"2014","journal-title":"Acta Ophthalmol."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1038\/eye.2008.342","article-title":"Ocular perfusion pressure and glaucoma: The Beijing Eye Study","volume":"23","author":"Xu","year":"2009","journal-title":"Eye"},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"463710","DOI":"10.1155\/2013\/463710","article-title":"Detection of Glaucoma in a Cohort of Chinese Subjects with Systemic Hypertension","volume":"2013","author":"Gangwani","year":"2013","journal-title":"J. Ophthalmol."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"e947","DOI":"10.1097\/MD.0000000000000947","article-title":"The Correlation of Retinal Nerve Fiber Layer Thickness with Blood Pressure in a Chinese Hypertensive Population","volume":"94","author":"Gangwani","year":"2015","journal-title":"Medicine"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"3399","DOI":"10.1167\/iovs.09-4867","article-title":"Distribution of Ocular Perfusion Pressure and Its Relationship with Open-Angle Glaucoma: The Singapore Malay Eye Study","volume":"51","author":"Zheng","year":"2010","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1136\/bjophthalmol-2017-311359","article-title":"Inter-relationship between ocular perfusion pressure, blood pressure, intraocular pressure profiles and primary open-angle glaucoma: The Singapore Epidemiology of Eye Diseases study","volume":"102","author":"Tham","year":"2018","journal-title":"Br. J. Ophthalmol."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3341\/kjo.2008.22.1.6","article-title":"Pulsatile Ocular Blood Flow in Healthy Koreans","volume":"22","author":"Kim","year":"2008","journal-title":"Korean J. Ophthalmol."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1167\/iovs.07-1146","article-title":"Heritability of Optic Disc and Cup Measured by the Heidelberg Retinal Tomography in Chinese: The Guangzhou Twin Eye Study","volume":"49","author":"He","year":"2008","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"28886","DOI":"10.3390\/ijms161226135","article-title":"An Updated Review on the Genetics of Primary Open Angle Glaucoma","volume":"16","author":"Kondkar","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1038\/s41467-020-20851-4","article-title":"Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries","volume":"12","author":"Gharahkhani","year":"2021","journal-title":"Nat. Commun."},{"key":"ref_111","doi-asserted-by":"crossref","unstructured":"Shin, H.-T., Yoon, B.W., and Seo, J.H. (2021). Analysis of risk allele frequencies of single nucleotide polymorphisms related to open-angle glaucoma in different ethnic groups. BMC Med. Genom., 14.","DOI":"10.1186\/s12920-021-00921-2"},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"107835","DOI":"10.1016\/j.exer.2019.107835","article-title":"The genetics of angle closure glaucoma","volume":"189","author":"Wang","year":"2019","journal-title":"Exp. Eye Res."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"108350","DOI":"10.1016\/j.exer.2020.108350","article-title":"In-depth analysis of eight susceptibility loci of primary angle closure glaucoma in Han Chinese","volume":"202","author":"Shi","year":"2021","journal-title":"Exp. Eye Res."},{"key":"ref_114","first-page":"3263","article-title":"Characterization of a novel mutation in the MYOC gene in a Chinese family with primary open-angle glaucoma","volume":"22","author":"Fan","year":"2020","journal-title":"Mol. Med. Rep."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1136\/bjophthalmol-2018-313069","article-title":"The clinical feature of myocilin Y437H mutation in a Chinese family with primary open-angle glaucoma","volume":"103","author":"Lei","year":"2019","journal-title":"Br. J. Ophthalmol."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.gene.2015.06.042","article-title":"Identification of a novel MYOC mutation in a Chinese family with primary open-angle glaucoma","volume":"571","author":"Yang","year":"2015","journal-title":"Gene"},{"key":"ref_117","first-page":"2052","article-title":"Association of MYOC and APOE promoter polymorphisms and primary open-angle glaucoma: A meta-analysis","volume":"8","author":"Guo","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1089\/gtmb.2014.0130","article-title":"Haplotype Analysis of Association of the MYOC Gene with Primary Angle-Closure Glaucoma in a Han Chinese Population","volume":"19","author":"Jin","year":"2015","journal-title":"Genet. Test. Mol. Biomark."},{"key":"ref_119","first-page":"1944","article-title":"A novel MYOC heterozygous mutation identified in a Chinese Uygur pedigree with primary open-angle glaucoma","volume":"18","author":"Cai","year":"2012","journal-title":"Mol. Vis."},{"key":"ref_120","first-page":"1431","article-title":"Sequence analysis of MYOC and CYP1B1 in a Chinese pedigree of primary open-angle glaucoma","volume":"17","author":"Chen","year":"2011","journal-title":"Mol. Vis."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s11033-009-9667-3","article-title":"New mutation in the MYOC gene and its association with primary open-angle glaucoma in a Chinese family","volume":"37","author":"Qu","year":"2010","journal-title":"Mol. Biol. Rep."},{"key":"ref_122","first-page":"89","article-title":"Multiple gene polymorphisms analysis revealed a different profile of genetic polymorphisms of primary open-angle glaucoma in northern Chinese","volume":"15","author":"Jia","year":"2009","journal-title":"Mol. Vis."},{"key":"ref_123","first-page":"1666","article-title":"Two novel myocilin mutations in a Chinese family with primary open-angle glaucoma","volume":"14","author":"Xie","year":"2008","journal-title":"Mol. Vis."},{"key":"ref_124","first-page":"413","article-title":"Presence of myocilin sequence variants in Japanese patients with open-angle glaucoma","volume":"14","author":"Mengkegale","year":"2008","journal-title":"Mol. Vis."},{"key":"ref_125","first-page":"667","article-title":"Role of CYP1B1, MYOC, OPTN and OPTC genes in adult-onset primary open-angle glaucoma: Predominance of CYP1B1 mutations in Indian patients","volume":"13","author":"Kumar","year":"2007","journal-title":"Mol. Vis."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"5368","DOI":"10.1167\/iovs.06-0196","article-title":"SNPs and Interaction Analyses of Noelin 2, Myocilin, and Optineurin Genes in Japanese Patients with Open-Angle Glaucoma","volume":"47","author":"Funayama","year":"2006","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_127","first-page":"111","article-title":"Gln48His is the prevalent myocilin mutation in primary open angle and primary congenital glaucoma phenotypes in India","volume":"11","author":"Chakrabarti","year":"2005","journal-title":"Mol. Vis."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1097\/0.ijg.0000138204.6d","article-title":"Novel MYOC Gene Mutation, Phe369Leu, in Japanese Patients with Primary Open-Angle Glaucoma Detected by Denaturing High-Performance Liquid Chromatography","volume":"13","author":"Ishikawa","year":"2004","journal-title":"J. Glaucoma"},{"key":"ref_129","first-page":"606","article-title":"Evaluation and understanding of myocilin mutations in Indian primary open angle glaucoma patients","volume":"9","author":"Kanagavalli","year":"2003","journal-title":"Mol. Vis."},{"key":"ref_130","first-page":"442","article-title":"Mutations in MYOC gene of Indian primary open angle glaucoma patients","volume":"8","author":"Mukhopadhyay","year":"2002","journal-title":"Mol. Vis."},{"key":"ref_131","first-page":"CR369-77","article-title":"Meta-analysis of association between optineurin gene and primary open-angle glaucoma","volume":"16","author":"Cheng","year":"2010","journal-title":"Med. Sci. Monit."},{"key":"ref_132","first-page":"1649","article-title":"A novel optineurin genetic mutation associated with open-angle glaucoma in a Chinese family","volume":"15","author":"Xiao","year":"2009","journal-title":"Mol. Vis."},{"key":"ref_133","first-page":"151","article-title":"Variation in optineurin (OPTN) allele frequencies between and within populations","volume":"13","author":"Pawar","year":"2007","journal-title":"Mol. Vis."},{"key":"ref_134","first-page":"816","article-title":"OPTN gene: Profile of patients with glaucoma from India","volume":"12","author":"Sripriya","year":"2006","journal-title":"Mol. Vis."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"4359","DOI":"10.1167\/iovs.03-1403","article-title":"Variants in Optineurin Gene and Their Association with Tumor Necrosis Factor-\u03b1 Polymorphisms in Japanese Patients with Glaucoma","volume":"45","author":"Funayama","year":"2004","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"3880","DOI":"10.1167\/iovs.02-0693","article-title":"Different optineurin mutation pattern in primary open-angle glaucoma","volume":"44","author":"Leung","year":"2003","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1136\/bjophthalmol-2014-306054","article-title":"Mutation spectrum ofCYP1B1in Chinese patients with primary open-angle glaucoma","volume":"99","author":"Gong","year":"2015","journal-title":"Br. J. Ophthalmol."},{"key":"ref_138","first-page":"786","article-title":"No association of genetic polymorphisms in CYP1B1 with primary open-angle glaucoma: A meta- and gene-based analysis","volume":"18","author":"Dong","year":"2012","journal-title":"Mol. Vis."},{"key":"ref_139","first-page":"841","article-title":"Leu432Val polymorphism in CYP1B1 as a susceptible factor towards predisposition to primary open-angle glaucoma","volume":"14","author":"Bhattacharjee","year":"2008","journal-title":"Mol. Vis."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s11427-018-9430-2","article-title":"Genome-wide analysis identified 17 new loci influencing intraocular pressure in Chinese population","volume":"62","author":"Huang","year":"2019","journal-title":"Sci. China Life Sci."},{"key":"ref_141","first-page":"548","article-title":"Expression-associated polymorphisms of CAV1-CAV2 affect intraocular pressure and high-tension glaucoma risk","volume":"21","author":"Kim","year":"2015","journal-title":"Mol. Vis."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/ceo.12201","article-title":"Association of single-nucleotide polymorphism rs4236601 near caveolin 1 and 2 with primary open-angle glaucoma: A meta-analysis","volume":"42","author":"Huang","year":"2014","journal-title":"Clin. Exp. Ophthalmol."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1038\/eye.2013.123","article-title":"Association study of genetic variants on chromosome 7q31 with susceptibility to normal tension glaucoma in a Japanese population","volume":"27","author":"Kato","year":"2013","journal-title":"Eye"},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1167\/iovs.61.10.37","article-title":"Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study","volume":"61","author":"Chai","year":"2020","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"3880","DOI":"10.1093\/hmg\/ddv128","article-title":"A common variant near TGFBR3 is associated with primary open angle glaucoma","volume":"24","author":"Yu","year":"2015","journal-title":"Hum. Mol. Genet."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1093\/hmg\/ddr060","article-title":"Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area","volume":"20","author":"Khor","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.ajo.2014.11.023","article-title":"Involvement of Genetic Variants Associated with Primary Open-Angle Glaucoma in Pathogenic Mechanisms and Family History of Glaucoma","volume":"159","author":"Mabuchi","year":"2015","journal-title":"Am. J. Ophthalmol."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1167\/iovs.11-8277","article-title":"Interactive Effects ofATOH7andRFTN1in Association with Adult-Onset Primary Open-Angle Glaucoma","volume":"53","author":"Chen","year":"2012","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"21167","DOI":"10.18632\/oncotarget.15504","article-title":"CDKN2B gene rs1063192 polymorphism decreases the risk of glaucoma","volume":"8","author":"Hu","year":"2017","journal-title":"Oncotarget"},{"key":"ref_150","doi-asserted-by":"crossref","unstructured":"Nakano, M., Ikeda, Y., Tokuda, Y., Fuwa, M., Omi, N., Ueno, M., Imai, K., Adachi, H., Kageyama, M., and Mori, K. (2012). Common Variants in CDKN2B-AS1 Associated with Optic-Nerve Vulnerability of Glaucoma Identified by Genome-Wide Association Studies in Japanese. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0033389"},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"2836","DOI":"10.1093\/hmg\/dds103","article-title":"A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma","volume":"21","author":"Osman","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"ref_152","doi-asserted-by":"crossref","unstructured":"Takamoto, M., Kaburaki, T., Mabuchi, A., Araie, M., Amano, S., Aihara, M., Tomidokoro, A., Iwase, A., Mabuchi, F., and Kashiwagi, K. (2012). Common Variants on Chromosome 9p21 Are Associated with Normal Tension Glaucoma. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0040107"},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"2914","DOI":"10.1167\/iovs.18-26489","article-title":"Association of Polymorphisms at the SIX1-SIX6 Locus with Primary Open-Angle Glaucoma","volume":"60","author":"Lu","year":"2019","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.exer.2018.12.014","article-title":"Association of the SIX6 locus with primary open angle glaucoma in southern Chinese and Japanese","volume":"180","author":"Rong","year":"2019","journal-title":"Exp. Eye Res."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"e23105","DOI":"10.1002\/jcla.23105","article-title":"Role of matrix metalloproteinase-9 gene polymorphisms in glaucoma: A hospital-based study in Chinese patients","volume":"34","author":"Zhao","year":"2020","journal-title":"J. Clin. Lab. Anal."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1080\/13816810.2016.1193877","article-title":"Matrix metalloproteinase-1 rs1799750 polymorphism and glaucoma: A meta-analysis","volume":"38","author":"He","year":"2017","journal-title":"Ophthalmic Genet."},{"key":"ref_157","first-page":"165","article-title":"Associations of polymorphisms of LOXL1 gene with primary open-angle glaucoma: A meta-analysis based on 5293 subjects","volume":"21","author":"Wu","year":"2015","journal-title":"Mol. Vis."},{"key":"ref_158","first-page":"550","article-title":"Lack of association between lysyl oxidase-like 1 polymorphisms and primary open angle glaucoma: A meta-analysis","volume":"7","author":"Sun","year":"2014","journal-title":"Int. J. Ophthalmol."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"12875","DOI":"10.1002\/jcb.28559","article-title":"Association between rs4938723 polymorphism and the risk of primary open-angle glaucoma (POAG) in a Chinese population","volume":"120","author":"Zhang","year":"2019","journal-title":"J. Cell. Biochem."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1080\/13816810.2017.1413661","article-title":"TP53 codon 72 polymorphism and the risk of glaucoma in a north Indian cohort: A genetic association study","volume":"39","author":"Gupta","year":"2018","journal-title":"Ophthalmic Genet."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"3756","DOI":"10.1167\/iovs.12-9818","article-title":"Association of TP53 Polymorphisms with Primary Open-Angle Glaucoma: A Meta-Analysis","volume":"53","author":"Guo","year":"2012","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"4110","DOI":"10.1167\/iovs.09-4974","article-title":"Association of Polymorphisms of Tumor Necrosis Factor and Tumor Protein p53 with Primary Open-Angle Glaucoma","volume":"51","author":"Fan","year":"2010","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.gene.2019.05.035","article-title":"Association of TNF-\u03b1 gene alterations (c.-238G > A, c.-308G > A, c.-857C > T, c.-863C > A) with primary glaucoma in north Indian cohort","volume":"709","author":"Passan","year":"2019","journal-title":"Gene"},{"key":"ref_164","first-page":"779","article-title":"Polymorphism in the TNF-\u03b1(\u2212863) locus associated with reduced risk of primary open angle glaucoma","volume":"18","author":"Wang","year":"2012","journal-title":"Mol. Vis."},{"key":"ref_165","doi-asserted-by":"crossref","unstructured":"Wang, Y., Zhou, Y.-F., Zhao, B.-Y., Gu, Z.-Y., and Li, S.-L. (2014). Apolipoprotein E gene \u03b54\u03b54 is associated with elevated risk of primary open angle glaucoma in Asians: A meta-analysis. BMC Med. Genet., 15.","DOI":"10.1186\/1471-2350-15-60"},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/01.ijg.0000212217.19804.a7","article-title":"Association of Apolipoprotein E Polymorphisms with Normal Tension Glaucoma in a Chinese Population","volume":"15","author":"Lam","year":"2006","journal-title":"J. Glaucoma"},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.ajo.2012.03.050","article-title":"Association of Toll-like Receptor 4 Gene Polymorphisms in Japanese Subjects with Primary Open-Angle, Normal-Tension, and Exfoliation Glaucoma","volume":"154","author":"Takano","year":"2012","journal-title":"Am. J. Ophthalmol."},{"key":"ref_168","first-page":"1629","article-title":"SNP rs1533428 at 2p16.3 as a marker for late-onset primary open-angle glaucoma","volume":"18","author":"Chen","year":"2012","journal-title":"Mol. Vis."},{"key":"ref_169","first-page":"2343","article-title":"Toll-like Receptor 4 gene polymorphisms do not associate with normal tension glaucoma in a Korean population","volume":"17","author":"Suh","year":"2011","journal-title":"Mol. Vis."},{"key":"ref_170","first-page":"1763","article-title":"Evaluation of NTF4 as a causative gene for primary open-angle glaucoma","volume":"18","author":"Chen","year":"2012","journal-title":"Mol. Vis."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"4937","DOI":"10.1167\/iovs.10-5553","article-title":"Variations inNTF4, VAV2, andVAV3Genes Are Not Involved with Primary Open-Angle and Primary Angle-Closure Glaucomas in an Indian Population","volume":"51","author":"Rao","year":"2010","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_172","first-page":"1640","article-title":"Identification of a novel mutation in the NTF4 gene that causes primary open-angle glaucoma in a Chinese population","volume":"16","author":"Vithana","year":"2010","journal-title":"Mol. Vis."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1167\/iovs.09-3979","article-title":"Replication of a Glaucoma Candidate Gene on 5q22.1 for Intraocular Pressure in Mongolian Populations: The GENDISCAN Project","volume":"51","author":"Lee","year":"2010","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_174","first-page":"646","article-title":"Different WDR36 mutation pattern in Chinese patients with primary open-angle glaucoma","volume":"15","author":"Fan","year":"2009","journal-title":"Mol. Vis."},{"key":"ref_175","first-page":"1912","article-title":"Association between primary open-angle glaucoma and WDR36 DNA sequence variants in Japanese","volume":"13","author":"Miyazawa","year":"2007","journal-title":"Mol. Vis."},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1167\/iovs.06-1213","article-title":"Lack of Association between Interleukin-1 Gene Cluster Polymorphisms and Glaucoma in Chinese Subjects","volume":"48","author":"How","year":"2007","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_177","first-page":"719","article-title":"Investigation of the association between interleukin-1beta polymorphism and normal tension glaucoma","volume":"13","author":"Wang","year":"2007","journal-title":"Mol. Vis."},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/IJG.0b013e3180300818","article-title":"Normal Tension Glaucoma is not Associated with the Interleukin -1\u03b1 (\u2212889) Genetic Polymorphism","volume":"16","author":"Wang","year":"2007","journal-title":"J. Glaucoma"},{"key":"ref_179","first-page":"1380","article-title":"Polymorphism in the IL-1alpha (-889) locus associated with elevated risk of primary open angle glaucoma","volume":"12","author":"Wang","year":"2006","journal-title":"Mol. Vis."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.bbrc.2013.02.003","article-title":"Molecular genetic analysis of primary open-angle glaucoma, normal tension glaucoma, and developmental glaucoma for the VAV2 and VAV3 gene variants in Japanese subjects","volume":"432","author":"Shi","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"839","DOI":"10.3109\/02713683.2014.958172","article-title":"Association between SNPs (rs1533428, rs12994401, rs10202118) on chromosome 2p16.3 and primary open angle glaucoma","volume":"40","author":"Meng","year":"2015","journal-title":"Curr. Eye Res."},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1038\/ng.3078","article-title":"Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma","volume":"46","author":"Chen","year":"2014","journal-title":"Nat. Genet."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1080\/13816810.2020.1747089","article-title":"Evaluation of the association between five genetic variants and primary open-angle glaucoma in a Han Chinese population","volume":"41","author":"Li","year":"2020","journal-title":"Ophthalmic Genet."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1038\/s41436-019-0507-0","article-title":"Mutant RAMP2 causes primary open-angle glaucoma via the CRLR-cAMP axis","volume":"21","author":"Gong","year":"2019","journal-title":"Genet. Med."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"4384","DOI":"10.1167\/iovs.17-22304","article-title":"Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus with Primary Angle-Closure Glaucoma in Chinese","volume":"58","author":"Tang","year":"2017","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_186","doi-asserted-by":"crossref","unstructured":"Nongpiur, M.E., Khor, C.C., Jia, H., Cornes, B.K., Chen, L.-J., Qiao, C., Nair, K.S., Cheng, C.-Y., Xu, L., and George, R. (2014). ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma. PLoS Genet., 10.","DOI":"10.1371\/journal.pgen.1004352"},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"BSR20160644","DOI":"10.1042\/BSR20160644","article-title":"Common polymorphisms of the hOGG1, APE1 and XRCC1 genes correlate with the susceptibility and clinicopathological features of primary angle-closure glaucoma","volume":"37","author":"Zeng","year":"2017","journal-title":"Biosci. Rep."},{"key":"ref_188","first-page":"1153","article-title":"XRCC1 and XPD DNA repair gene polymorphisms: A potential risk factor for glaucoma in the Pakistani population","volume":"17","author":"Yousaf","year":"2011","journal-title":"Mol. Vis."},{"key":"ref_189","doi-asserted-by":"crossref","unstructured":"Wang, S., Zhuang, W., Ma, J., Xu, M., Piao, S., Hao, J., Zhang, W., Chi, H., Xue, Z., and Ha, S. (2018). Association of Genes implicated in primary angle-closure Glaucoma and the ocular biometric parameters of anterior chamber depth and axial length in a northern Chinese population. BMC Ophthalmol., 18.","DOI":"10.1186\/s12886-018-0934-8"},{"key":"ref_190","first-page":"128","article-title":"Association of frizzled-related protein (MFRP) and heat shock protein 70 (HSP70) single nucleotide polymorphisms with primary angle closure in a Han Chinese population: Jiangsu Eye Study","volume":"19","author":"Shi","year":"2013","journal-title":"Mol. Vis."},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1080\/13816810.2017.1342132","article-title":"Association of catalase polymorphisms with primary open-angle glaucoma in a Chinese population","volume":"39","author":"Gong","year":"2018","journal-title":"Ophthalmic Genet."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1038\/eye.2015.74","article-title":"A novel truncation mutation in GJA1 associated with open angle glaucoma and microcornea in a large Chinese family","volume":"29","author":"Huang","year":"2015","journal-title":"Eye"},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3109\/13816810.2014.985844","article-title":"Association of SOD2 Polymorphisms with Primary Open Angle Glaucoma in a Chinese Population","volume":"36","author":"Zhou","year":"2015","journal-title":"Ophthalmic Genet."},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/jcmm.12201","article-title":"Family-based analysis identified CD2 as a susceptibility gene for primary open angle glaucoma in Chinese Han population","volume":"18","author":"Liu","year":"2014","journal-title":"J. Cell. Mol. Med."},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.gene.2013.06.031","article-title":"Are glutathione S-transferase polymorphisms (GSTM1, GSTT1) associated with primary open angle glaucoma? A meta-analysis","volume":"527","author":"Lu","year":"2013","journal-title":"Gene"},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.gene.2013.05.032","article-title":"Association of glutathione S-transferase polymorphisms (GSTM1 and GSTT1) with primary open-angle glaucoma: An evidence-based meta-analysis","volume":"526","author":"Huang","year":"2013","journal-title":"Gene"},{"key":"ref_197","doi-asserted-by":"crossref","unstructured":"Guo, Y., Chen, X., Zhang, H., Li, N., Yang, X., Cheng, W., and Zhao, K. (2012). Association of OPA1 Polymorphisms with NTG and HTG: A Meta-Analysis. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0042387"},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1097\/01.ijg.0000137870.25779.40","article-title":"Investigation of the Association between OPA1 Polymorphisms and Normal-Tension Glaucoma in Korea","volume":"13","author":"Woo","year":"2004","journal-title":"J. Glaucoma"},{"key":"ref_199","first-page":"792","article-title":"Investigation of the association between SLC1A3 gene polymorphisms and normal tension glaucoma","volume":"17","author":"Yasumura","year":"2011","journal-title":"Mol. Vis."},{"key":"ref_200","first-page":"1874","article-title":"Genotyping HLA-DRB1 and HLA-DQB1 alleles in Japanese patients with normal tension glaucoma","volume":"16","author":"Suzuki","year":"2010","journal-title":"Mol. Vis."},{"key":"ref_201","first-page":"462","article-title":"Analysis of microsatellite polymorphisms within the GLC1F locus in Japanese patients with normal tension glaucoma","volume":"16","author":"Murakami","year":"2010","journal-title":"Mol. Vis."},{"key":"ref_202","first-page":"1016","article-title":"Investigations on the association between normal tension glaucoma and single nucleotide polymorphisms of the endothelin-1 and endothelin receptor genes","volume":"12","author":"Kim","year":"2006","journal-title":"Mol. Vis."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/9\/2486\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:03:29Z","timestamp":1760137409000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/9\/2486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,28]]},"references-count":202,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2022,5]]}},"alternative-id":["jcm11092486"],"URL":"https:\/\/doi.org\/10.3390\/jcm11092486","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,28]]}}}