{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T02:29:24Z","timestamp":1762050564235,"version":"build-2065373602"},"reference-count":30,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Electrodiagnostic studies (EDXs) are the confirmative diagnostic tool for carpal tunnel syndrome (CTS). Previous studies have evaluated the relationship between EDXs and ultrasonography (US) but not with X-rays. Recently, many studies on the diagnostic value of X-rays in various diseases have been reported, but data on CTS are lacking. We evaluated the relationship between electrodiagnostic parameters and roentgenographic and ultrasonographic features in CTS and investigated the usefulness of X-rays and US for CTS. This retrospective study included 97 wrists of 62 patients. All patients with suspected CTS underwent EDXs, wrist US, and wrist X-rays. The CTS patients were classified into mild, moderate, and severe groups. The roentgenographic features included the ulnar variance (UV) and the anteroposterior diameter of the wrist (APDW), and the ultrasonographic features included the flattening ratio (FR) and the thickest anteroposterior diameter of the median nerve (TAPDM). Most EDX parameters showed significant correlations with roentgenographic and US features. The electrodiagnostic severity was also correlated with all imaging features. Therefore, both wrist X-rays and wrist US can be useful for the diagnosis of CTS as supplements to EDXs.<\/jats:p>","DOI":"10.3390\/jcm11102808","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T13:06:23Z","timestamp":1652706383000},"page":"2808","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Correlation between Electrodiagnostic Study and Imaging Features in Patients with Suspected Carpal Tunnel Syndrome"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3320-0044","authenticated-orcid":false,"given":"Jae Min","family":"Song","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, Konyang University College of Medicine, Daejeon 35365, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jungyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Konyang University College of Medicine, Daejeon 35365, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Jin","family":"Chae","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Konyang University College of Medicine, Daejeon 35365, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Bum","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Konyang University College of Medicine, Daejeon 35365, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yung Jin","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Konyang University College of Medicine, Daejeon 35365, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheol Mog","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Konyang University College of Medicine, Daejeon 35365, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6192-2610","authenticated-orcid":false,"given":"Jieun","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Konyang University College of Medicine, Daejeon 35365, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4170-0762","authenticated-orcid":false,"given":"Mi Jin","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Konyang University College of Medicine, Daejeon 35365, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1056\/NEJM199312303292707","article-title":"Entrapment neuropathies of the upper extremities","volume":"329","author":"Dawson","year":"1993","journal-title":"N. Engl. J. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/00003086-197203000-00007","article-title":"The carpal-tunnel syndrome. Clinical evaluation of 598 hands","volume":"83","author":"Phalen","year":"1972","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1002\/mus.880161220","article-title":"Literature review of the usefulness of nerve conduction studies and electromyography for the evaluation of patients with carpal tunnel syndrome. AAEM Quality Assurance Committee","volume":"16","author":"Jablecki","year":"1993","journal-title":"Muscle Nerve"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1148\/radiol.2321030071","article-title":"Carpal tunnel syndrome: Diagnostic usefulness of sonography","volume":"232","author":"Wong","year":"2004","journal-title":"Radiology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"531","DOI":"10.7863\/jum.1991.10.10.531","article-title":"High-resolution ultrasonography of the carpal tunnel","volume":"10","author":"Buchberger","year":"1991","journal-title":"J. Ultrasound Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"793","DOI":"10.2214\/ajr.159.4.1529845","article-title":"Carpal tunnel syndrome: Diagnosis with high-resolution sonography","volume":"159","author":"Buchberger","year":"1992","journal-title":"AJR Am. J. Roentgenol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"681","DOI":"10.2214\/ajr.173.3.10470903","article-title":"Sonography in the diagnosis of carpal tunnel syndrome","volume":"173","author":"Duncan","year":"1999","journal-title":"AJR Am. J. Roentgenol."},{"key":"ref_8","first-page":"336","article-title":"High-resolution ultrasonography in the study of carpal tunnel syndrome","volume":"93","author":"Ferrari","year":"1997","journal-title":"Radiol. Med."},{"key":"ref_9","first-page":"21","article-title":"Correlation of Ultrasonography with the Nerve Conduction Study in Carpal Tunnel Syndrome of Koreans","volume":"8","author":"Kim","year":"2006","journal-title":"J. Korean Assoc. EMG Electrodiagn. Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.clinph.2008.01.101","article-title":"The ultrasonographic wrist-to-forearm median nerve area ratio in carpal tunnel syndrome","volume":"119","author":"Massey","year":"2008","journal-title":"Clin. Neurophysiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1177\/0846537120941671","article-title":"Artificial Intelligence Solutions for Analysis of X-ray Images","volume":"72","author":"Adams","year":"2021","journal-title":"Can. Assoc. Radiol. J."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12891-020-03254-w","article-title":"Radiographic characteristics of wrists in idiopathic carpal tunnel syndrome patients","volume":"21","author":"Ikeda","year":"2020","journal-title":"BMC Musculoskelet. Disord."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1136\/bmj.2.6145.1125-a","article-title":"Tinel\u2019s sign and the carpal tunnel syndrome","volume":"2","author":"Stewart","year":"1978","journal-title":"Br. Med. J."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.3928\/0147-7447-19921101-08","article-title":"Tinel\u2019s sign and Phalen\u2019s test in carpal tunnel syndrome","volume":"15","author":"Kuschner","year":"1992","journal-title":"Orthopedics"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/0003-9993(94)90136-8","article-title":"Reverse Phalen\u2019s maneuver as an aid in diagnosing carpal tunnel syndrome","volume":"75","author":"Werner","year":"1994","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_16","unstructured":"Preston, D.C., and Shapiro, B.E. (2020). Routine upper extremity, facial, and phrenic nerve conduction techniques. Electromyography and Neuromuscular Disorders E-Book: Clinical-Electrophysiologic-Ultrasound Correlations, Elsevier Health Sciences. [4th ed.]."},{"key":"ref_17","unstructured":"Preston, D.C., and Shapiro, B.E. (2020). Median neuropathy at the wrist. Electromyography and Neuromuscular Disorders E-Book: Clinical-Electrophysiologic-Ultrasound Correlations, Elsevier Health Sciences. [4th ed.]."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1002\/1097-4598(200008)23:8<1280::AID-MUS20>3.0.CO;2-Y","article-title":"A neurophysiological grading scale for carpal tunnel syndrome","volume":"23","author":"Bland","year":"2000","journal-title":"Muscle Nerve Off. J. Am. Assoc. Electrodiagn. Med."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"W181","DOI":"10.2214\/AJR.11.7012","article-title":"Correlation between the severity of carpal tunnel syndrome and color Doppler sonography findings","volume":"198","author":"Mohammadi","year":"2012","journal-title":"Am. J. Roentgenol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1007\/s11552-015-9772-9","article-title":"A structured review addressing the use of radiographic measures of alignment and the definition of acceptability in patients with distal radius fractures","volume":"10","author":"Lalone","year":"2015","journal-title":"Hand"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1002\/mus.22208","article-title":"Electrodiagnostic evaluation of carpal tunnel syndrome","volume":"44","author":"Werner","year":"2011","journal-title":"Muscle Nerve"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"479","DOI":"10.3349\/ymj.2003.44.3.479","article-title":"Tenelectrodes: A new stimulator for inching technique in the diagnosis of carpal tunnel syndrome","volume":"44","author":"Kang","year":"2003","journal-title":"Yonsei Med. J."},{"key":"ref_23","first-page":"1","article-title":"Ulnar variance: Facts and fiction review article","volume":"60","year":"1994","journal-title":"Acta Orthop. Belg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1097\/SAP.0000000000001640","article-title":"Cross-sectional Area Just Proximal to the Carpal Tunnel According to the Ulnar Variances: Positive Ulnar Variance and Carpal Tunnel Syndrome","volume":"82","author":"Cha","year":"2019","journal-title":"Ann. Plast. Surg."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1212\/WNL.35.11.1599","article-title":"Carpal tunnel syndrome: Role of carpal canal size","volume":"35","author":"Bleecker","year":"1985","journal-title":"Neurology"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1136\/bmj.280.6227.1297","article-title":"Idiopathic carpal tunnel syndrome caused by carpal stenosis","volume":"280","author":"Dekel","year":"1980","journal-title":"Br. Med. J."},{"key":"ref_27","first-page":"254","article-title":"Carpal tunnel area as a risk factor for carpal tunnel syndrome","volume":"13","author":"Habes","year":"1990","journal-title":"Muscle Nerve Off. J. Am. Assoc. Electrodiagn. Med."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1136\/jnnp.2004.051060","article-title":"Quantitative MRI of the wrist and nerve conduction studies in patients with idiopathic carpal tunnel syndrome","volume":"76","author":"Uchiyama","year":"2005","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1148\/radiology.171.3.2541464","article-title":"Carpal tunnel: MR imaging. Part II. Carpal tunnel syndrome","volume":"171","author":"Mesgarzadeh","year":"1989","journal-title":"Radiology"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"307","DOI":"10.2214\/ajr.148.2.307","article-title":"MR imaging of the carpal tunnel: Normal anatomy and preliminary findings in the carpal tunnel syndrome","volume":"148","author":"Middleton","year":"1987","journal-title":"Am. J. Roentgenol."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/10\/2808\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:11:25Z","timestamp":1760137885000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/10\/2808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,16]]},"references-count":30,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2022,5]]}},"alternative-id":["jcm11102808"],"URL":"https:\/\/doi.org\/10.3390\/jcm11102808","relation":{},"ISSN":["2077-0383"],"issn-type":[{"type":"electronic","value":"2077-0383"}],"subject":[],"published":{"date-parts":[[2022,5,16]]}}}