{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T02:24:18Z","timestamp":1791685458079,"version":"4.3.4"},"reference-count":97,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T00:00:00Z","timestamp":1653868800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Indications for transcatheter aortic valve replacement (TAVR) have steadily increased over the last decade since the first trials including inoperable or very high risk patients. Thus, TAVR is now the most common treatment of aortic valve stenosis in elderly patients (vs. surgical aortic valve replacement -SAVR-). In this review, we summarize the current indications of TAVR and explore future directions in which TAVR indications can expand.<\/jats:p>","DOI":"10.3390\/jcm11113090","type":"journal-article","created":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T10:05:14Z","timestamp":1653905114000},"page":"3090","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Evolving Indications of Transcatheter Aortic Valve Replacement\u2014Where Are We Now, and Where Are We Going"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2131-6763","authenticated-orcid":false,"given":"Jules","family":"Mesnier","sequence":"first","affiliation":[{"name":"Quebec Heart and Lung Institute, Laval University, Quebec City, QC G1V 4G5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0012-1289","authenticated-orcid":false,"given":"Vassili","family":"Panagides","sequence":"additional","affiliation":[{"name":"Quebec Heart and Lung Institute, Laval University, Quebec City, QC G1V 4G5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8269-2244","authenticated-orcid":false,"given":"Jorge","family":"Nuche","sequence":"additional","affiliation":[{"name":"Quebec Heart and Lung Institute, Laval University, Quebec City, QC G1V 4G5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Rod\u00e9s-Cabau","sequence":"additional","affiliation":[{"name":"Quebec Heart and Lung Institute, Laval University, Quebec City, QC G1V 4G5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.jacc.2003.11.026","article-title":"Early experience with percutaneous transcatheter implantation of heart valve pros-thesis for the treatment of end-stage inoperable patients with calcific aortic stenosis","volume":"43","author":"Cribier","year":"2004","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1056\/NEJMoa1103510","article-title":"Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients","volume":"364","author":"Smith","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1056\/NEJMoa1400590","article-title":"Transcatheter Aortic-Valve Replacement with a Self-Expanding Prosthesis","volume":"370","author":"Adams","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1056\/NEJMoa1514616","article-title":"Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients","volume":"374","author":"Leon","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1056\/NEJMoa1700456","article-title":"Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients","volume":"376","author":"Reardon","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1056\/NEJMoa1814052","article-title":"Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients","volume":"380","author":"Mack","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1056\/NEJMoa1816885","article-title":"Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients","volume":"380","author":"Popma","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1016\/j.athoracsur.2021.03.043","article-title":"STS Adult Cardiac Surgery Database: 2021 Update on Outcomes, Quality, and Research","volume":"111","author":"Bowdish","year":"2021","journal-title":"Ann. Thorac. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.jacc.2021.12.020","article-title":"TAVR Sustains Its Promise in Low-Risk Patients, But the Journey Is Far from Over","volume":"79","author":"Thourani","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_10","first-page":"435","article-title":"Asymptomatic severe aortic stenosis, bicuspid aortic valves and moderate aortic stenosis in heart failure: New indications for transcatheter aortic valve implantation","volume":"31","author":"Simonato","year":"2021","journal-title":"Trends Cardiovasc. Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/eurheartj\/ehab395","article-title":"2021 ESC\/EACTS Guidelines for the management of valvular heart disease","volume":"43","author":"Vahanian","year":"2022","journal-title":"Eur. Heart J."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jacc.2020.11.035","article-title":"2020 ACC\/AHA Guideline for the Management of Patients with Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"77","author":"Otto","year":"2021","journal-title":"J. Am. College Cardiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1093\/eurheartj\/ehq076","article-title":"Usefulness of exercise-stress echocardiography for risk stratification of true asymptomatic patients with aortic valve stenosis","volume":"31","author":"Hachicha","year":"2010","journal-title":"Eur. Heart J."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1056\/NEJMc2016167","article-title":"Early Surgery or Conservative Care for Asymptomatic Aortic Stenosis","volume":"383","author":"Garry","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"ref_15","first-page":"384","article-title":"B-type natriuretic peptide in patients with asymptomatic severe aortic stenosis","volume":"105","author":"Nakatsuma","year":"2018","journal-title":"Heart"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1016\/j.jacc.2015.10.001","article-title":"Initial Surgical Versus Conservative Strategies in Patients with Asymptomatic Severe Aortic Stenosis","volume":"66","author":"Taniguchi","year":"2015","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1161\/CIRCULATIONAHA.119.041080","article-title":"Contemporary Presentation and Management of Valvular Heart Disease: The EU-RObservational Research Programme Valvular Heart Disease II Survey","volume":"140","author":"Iung","year":"2019","journal-title":"Circulation"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1016\/j.athoracsur.2006.07.043","article-title":"Malignant Natural History of Asymptomatic Severe Aortic Stenosis: Benefit of Aortic Valve Replacement","volume":"82","author":"Pai","year":"2006","journal-title":"Ann. Thorac. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1161\/CIRCULATIONAHA.116.025457","article-title":"Stress Testing in Asymptomatic Aortic Stenosis","volume":"135","author":"Redfors","year":"2017","journal-title":"Circulation"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/s11936-017-0551-5","article-title":"Exercise Testing and Stress Imaging in Aortic Valve Disease","volume":"19","author":"Pierard","year":"2017","journal-title":"Curr. Treat. Options Cardiovasc. Med."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"3290","DOI":"10.1161\/CIRCULATIONAHA.104.495903","article-title":"Outcome of 622 Adults with Asymptomatic, Hemodynamically Significant Aortic Stenosis During Prolonged Follow-Up","volume":"111","author":"Pellikka","year":"2005","journal-title":"Circulation"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1016\/j.jacc.2016.02.057","article-title":"Natural History, Diagnostic Approaches, and Therapeutic Strategies for Patients with Asymptomatic Severe Aortic Stenosis","volume":"67","author":"Stone","year":"2016","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1161\/CIRCULATIONAHA.121.057639","article-title":"Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis: The AVATAR Trial","volume":"145","author":"Banovic","year":"2022","journal-title":"Circulation"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ahj.2019.02.018","article-title":"Rationale and design of the randomized, controlled Early Valve Replacement Guided by Biomarkers of Left Ventricular Decompensation in Asymptomatic Patients with Severe Aortic Stenosis (EVOLVED) trial","volume":"212","author":"Bing","year":"2019","journal-title":"Am. Heart J."},{"key":"ref_25","unstructured":"Genereux, P. (2017, January 16). Rationale and Status Update of the EARLY TAVR Trial Asymptomatic Severe AS Patients. Proceedings of the TCT 2017, Denver, CO, USA."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"e67","DOI":"10.1161\/CIR.0000000000000558","article-title":"Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association","volume":"137","author":"Benjamin","year":"2018","journal-title":"Circulation"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1016\/j.jacc.2017.03.023","article-title":"Prognostic implications of moderate aortic stenosis in patients with left ventricular systolic dysfunction","volume":"69","author":"Clavel","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1016\/j.jacc.2019.08.004","article-title":"Poor Long-Term Survival in Patients with Moderate Aortic Stenosis","volume":"74","author":"Strange","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1093\/eurheartj\/ehv701","article-title":"Aortic valve surgery and survival in patients with moderate or severe aortic stenosis and left ventricular dysfunction","volume":"37","author":"Samad","year":"2016","journal-title":"Eur. Heart J."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.1016\/j.jacc.2021.04.014","article-title":"Moderate Aortic Stenosis in Patients with Heart Failure and Reduced Ejection Fraction","volume":"77","author":"Jean","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.ahj.2016.08.009","article-title":"Rationale and design of the Transcatheter Aortic Valve Replacement to UNload the Left ventricle in patients with ADvanced heart failure (TAVR UNLOAD) trial","volume":"182","author":"Spitzer","year":"2016","journal-title":"Am. Heart J."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.athoracsur.2014.10.070","article-title":"Long-Term Durability of Bioprosthetic Aortic Valves: Implications From 12,569 Implants","volume":"99","author":"Johnston","year":"2015","journal-title":"Ann. Thorac. Surg."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1016\/S0140-6736(15)60308-7","article-title":"5-year outcomes of transcatheter aortic valve replacement or surgical aortic valve re-placement for high surgical risk patients with aortic stenosis (PARTNER 1): A randomised controlled trial","volume":"385","author":"Mack","year":"2015","journal-title":"Lancet"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/j.jcin.2015.03.024","article-title":"5-Year Outcomes After Transcatheter Aortic Valve Implantation with CoreValve Prosthesis","volume":"8","author":"Barbanti","year":"2015","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"2912","DOI":"10.1093\/eurheartj\/ehab375","article-title":"Eight-year outcomes for patients with aortic valve stenosis at low surgical risk randomized to transcatheter vs. surgical aortic valve replacement","volume":"42","author":"Thyregod","year":"2021","journal-title":"Eur. Heart J."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.jacc.2018.10.078","article-title":"Long-Term Durability of Transcatheter Aortic Valve Prostheses","volume":"73","author":"Blackman","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"VARC-3 Writing Committee, G\u00e9n\u00e9reux, P., Piazza, N., Alu, M.C., Nazif, T., Hahn, R.T., Pibarot, P., Bax, J.J., Leipsic, J.A., and Blanke, P. (2021). Valve Academic Research Consortium 3: Updated endpoint definitions for aortic valve clinical research. Eur. Heart J., 42, 1825\u20131857.","DOI":"10.1093\/eurheartj\/ehaa799"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1093\/eurheartj\/ehx785","article-title":"Pacemaker implantation rate after transcatheter aortic valve implantation with early and new-generation devices: A systematic review","volume":"39","author":"Delgado","year":"2018","journal-title":"Eur. Heart J."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.jacc.2019.07.014","article-title":"Management of Conduction Disturbances Associated with Transcatheter Aortic Valve Replacement","volume":"74","author":"Ellenbogen","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.1093\/eurheartj\/ehz924","article-title":"Clinical impact of conduction disturbances in transcatheter aortic valve replacement recipients: A systematic review and meta-analysis","volume":"41","author":"Faroux","year":"2020","journal-title":"Eur. Heart J."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.jcin.2021.10.002","article-title":"Permanent Pacemaker Reduction Using Cusp-Overlapping Projection in TAVR","volume":"15","author":"Pascual","year":"2022","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.jacc.2019.06.012","article-title":"Coronary Artery Disease and Transcatheter Aortic Valve Replacement","volume":"74","author":"Faroux","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1080\/17434440.2018.1536427","article-title":"Principles of TAVR valve design, modelling, and testing","volume":"15","author":"Rotman","year":"2018","journal-title":"Expert Rev. Med. Devices"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1016\/j.jacc.2018.01.057","article-title":"Coronary Angiography and Percutaneous Coronary Intervention after Transcatheter Aortic Valve Replacement","volume":"71","author":"Yudi","year":"2018","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1016\/j.jcin.2021.05.007","article-title":"Feasibility of Coronary Access in Patients with Acute Coronary Syndrome and Previous TAVR","volume":"14","author":"Kim","year":"2021","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1016\/j.jacc.2021.03.014","article-title":"ST-Segment Elevation Myocardial Infarction Following Transcatheter Aortic Valve Replacement","volume":"77","author":"Faroux","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1016\/j.jcin.2020.07.006","article-title":"Coronary Cannulation after Transcatheter Aortic Valve Replacement: The RE-ACCESS Study","volume":"13","author":"Barbanti","year":"2020","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"e1169","DOI":"10.4244\/EIJ-D-18-00098","article-title":"Independent impact of extent of coronary artery disease and percutaneous revas-cularisation on 30-day and one-year mortality after TAVI: A meta-analysis of adjusted observational results","volume":"14","author":"Verardi","year":"2018","journal-title":"EuroIntervention"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"e006092","DOI":"10.1161\/JAHA.117.006092","article-title":"Impact of Coronary Artery Disease on 30-Day and 1-Year Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement: A Meta-Analysis","volume":"6","author":"Sankaramangalam","year":"2017","journal-title":"J. Am. Heart Assoc."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/s12471-018-1149-6","article-title":"CTCA for detection of significant coronary artery disease in routine TAVI work-up: A systematic review and meta-analysis","volume":"26","author":"Vendrik","year":"2018","journal-title":"Neth. Heart J."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"e285","DOI":"10.4244\/EIJ-D-19-01001","article-title":"Angiography-based quantitative flow ratio versus fractional flow reserve in patients with coronary artery disease and severe aortic stenosis","volume":"16","author":"Paradis","year":"2020","journal-title":"EuroIntervention"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.jcmg.2021.09.013","article-title":"Combined cCTA and TAVR Planning for Ruling Out Significant CAD","volume":"15","author":"Gohmann","year":"2021","journal-title":"JACC Cardiovasc. Imaging"},{"key":"ref_53","first-page":"31","article-title":"Percutaneous coronary intervention in stable angina (ORBITA): A double-blind, randomised controlled trial","volume":"391","author":"Thompson","year":"2017","journal-title":"Lancet"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1056\/NEJMoa1915922","article-title":"Initial Invasive or Conservative Strategy for Stable Coronary Disease","volume":"382","author":"Maron","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1161\/CIRCULATIONAHA.120.047987","article-title":"Myocardial Infarction in the ISCHEMIA Trial: Impact of Different Definitions on Incidence, Prognosis, and Treatment Comparisons","volume":"143","author":"Chaitman","year":"2021","journal-title":"Circulation"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"Knuuti","year":"2020","journal-title":"Eur. Heart J."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1016\/j.amjcard.2012.01.390","article-title":"Frequency of Congenitally Bicuspid Aortic Valves in Patients \u226580 Years of Age Undergoing Aortic Valve Replacement for Aortic Stenosis (With or Without Aortic Regurgitation) and Implications for Transcatheter Aortic Valve Implantation","volume":"109","author":"Roberts","year":"2012","journal-title":"Am. J. Cardiol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1161\/CIRCULATIONAHA.120.048048","article-title":"Transcatheter Aortic Valve Replacement in Bicuspid Aortic Valve Stenosis","volume":"143","author":"Vincent","year":"2021","journal-title":"Circulation"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"e007107","DOI":"10.1161\/CIRCINTERVENTIONS.118.007107","article-title":"Bicuspid Aortic Valve Anatomy and Relationship with Devices: The BAVARD Mul-ticenter Registry: A European Picture of Contemporary Multidetector Computed Tomography Sizing for Bicuspid Valves","volume":"12","author":"Tchetche","year":"2019","journal-title":"Circ. Cardiovasc. Interv."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.jacc.2020.07.005","article-title":"Bicuspid Aortic Valve Morphology and Outcomes After Transcatheter Aortic Valve Replacement","volume":"76","author":"Yoon","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"3663","DOI":"10.1016\/j.jbiomech.2015.08.012","article-title":"Leaflet stress and strain distributions following incomplete transcatheter aortic valve expansion","volume":"48","author":"Abbasi","year":"2015","journal-title":"J. Biomech."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1001\/jama.300.11.1317","article-title":"Outcomes in Adults with Bicuspid Aortic Valves","volume":"300","author":"Tzemos","year":"2008","journal-title":"JAMA"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/j.jcin.2010.08.016","article-title":"Transcatheter Aortic Valve Implantation in Patients with Bicuspid Aortic Valve Stenosis","volume":"3","author":"Wijesinghe","year":"2010","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1016\/j.jcin.2020.03.022","article-title":"Transcatheter Aortic Valve Replacement in Bicuspid Versus Tricuspid Aortic Valves From the STS\/ACC TVT Registry","volume":"13","author":"Forrest","year":"2020","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1001\/jama.2019.7108","article-title":"Association Between Transcatheter Aortic Valve Replacement for Bicuspid vs Tricuspid Aortic Stenosis and Mortality or Stroke","volume":"321","author":"Makkar","year":"2019","journal-title":"JAMA"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"2579","DOI":"10.1016\/j.jacc.2020.09.605","article-title":"Brain Injury After Transcatheter Replacement of Bicuspid Versus Tricuspid Aortic Valves","volume":"76","author":"Fan","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1016\/j.athoracsur.2019.08.023","article-title":"Aortic Valve Replacement in Bioprosthetic Failure: Insights from The Society of Thoracic Surgeons National Database","volume":"110","author":"Kalra","year":"2019","journal-title":"Ann. Thorac. Surg."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1016\/j.jacc.2017.02.057","article-title":"Transcatheter Aortic Valve Implantation Within Degenerated Aortic Surgical Biopros-theses: PARTNER 2 Valve-in-Valve Registry","volume":"69","author":"Webb","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"e007038","DOI":"10.1161\/CIRCINTERVENTIONS.118.007038","article-title":"Long-Term Outcomes after Transcatheter Aortic Valve-in-Valve Replacement","volume":"11","author":"Urena","year":"2018","journal-title":"Circ. Cardiovasc. Interv."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.jacc.2018.04.074","article-title":"Transcatheter Aortic Valve Replacement of Failed Surgically Implanted Bio-prostheses: The STS\/ACC Registry","volume":"72","author":"Tuzcu","year":"2018","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.jcin.2020.10.020","article-title":"Valve-in-Valve Transcatheter Aortic Valve Replacement Versus Redo Surgical Aortic Valve Replacement: An Updated Meta-Analysis","volume":"14","author":"Simonato","year":"2021","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1093\/eurheartj\/ehaa544","article-title":"Long-term outcomes after transcatheter aortic valve implantation in failed biopros-thetic valves","volume":"41","author":"Bleiziffer","year":"2020","journal-title":"Eur. Heart J."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1093\/eurheartj\/ehx455","article-title":"Incidence, predictors, and clinical outcomes of coronary obstruction following transcatheter aortic valve replacement for degenerative bioprosthetic surgical valves: Insights from the VIVID registry","volume":"39","author":"Ribeiro","year":"2017","journal-title":"Eur. Heart J."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1001\/jama.2014.7246","article-title":"Transcatheter Aortic Valve Implantation in Failed Bioprosthetic Surgical Valves","volume":"312","author":"Dvir","year":"2014","journal-title":"JAMA"},{"key":"ref_75","first-page":"20","article-title":"Bioprosthetic Valve Fracture during Valve-in-valve TAVR: Bench to Bedside","volume":"13","author":"Saxon","year":"2017","journal-title":"Interv. Cardiol. Rev. Res. Resour."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"528","DOI":"10.21037\/acs-2020-av-20","article-title":"Bioprosthetic valve fracture to facilitate valve-in-valve transcatheter aortic valve repair","volume":"9","author":"Allen","year":"2020","journal-title":"Ann. Cardiothorac. Surg."},{"key":"ref_77","first-page":"491","article-title":"Valve-in-Valve Transcatheter Aortic Valve Replacement, with Present-Day Innovations and Up-to-Date Techniques","volume":"10","author":"Salem","year":"2021","journal-title":"Interv. Cardiol. Clin."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.jcin.2018.01.247","article-title":"Transcatheter Laceration of Aortic Leaflets to Prevent Coronary Obstruction During Transcatheter Aortic Valve Replacement: Concept to First-in-Human","volume":"11","author":"Khan","year":"2018","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1016\/j.jcin.2019.03.035","article-title":"The BASILICA Trial: Prospective Multicenter Investigation of Intentional Leaflet Laceration to Prevent TAVR Coronary Obstruction","volume":"12","author":"Khan","year":"2019","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"2528","DOI":"10.1016\/j.jcin.2020.06.016","article-title":"Coronary Access After TAVR-in-TAVR as Evaluated by Multidetector Computed Tomography","volume":"13","author":"Landes","year":"2020","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1016\/j.jacc.2020.02.051","article-title":"Repeat Transcatheter Aortic Valve Replacement for Transcatheter Prosthesis Dys-function","volume":"75","author":"Landes","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.jcin.2020.10.056","article-title":"Balloon-Assisted BASILICA to Facilitate Redo TAVR","volume":"14","author":"Greenbaum","year":"2021","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"e021871","DOI":"10.1161\/JAHA.121.021871","article-title":"Transcatheter Aortic Valve Replacement with Self-Expandable Supra-Annular Valves for Degenerated Surgical Bioprostheses: Insights from Transcatheter Valve Therapy Registry","volume":"10","author":"Dallan","year":"2021","journal-title":"J. Am. Heart Assoc."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jacc.2017.04.053","article-title":"Temporal Trends in Transcatheter Aortic Valve Replacement in France","volume":"70","author":"Auffret","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.jacc.2016.11.033","article-title":"2016 Annual Report of The Society of Thoracic Surgeons\/American College of Cardiology Transcatheter Valve Therapy Registry","volume":"69","author":"Grover","year":"2016","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.jcin.2019.01.219","article-title":"Outcomes Following Subclavian and Axillary Artery Access for Transcatheter Aortic Valve Replacement","volume":"12","author":"Dahle","year":"2019","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"e006388","DOI":"10.1161\/CIRCINTERVENTIONS.118.006388","article-title":"Transcarotid Compared with Other Alternative Access Routes for Transcatheter Aortic Valve Replacement","volume":"11","author":"Chamandi","year":"2018","journal-title":"Circ. Cardiovasc. Interv."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1161\/CIRCULATIONAHA.114.012525","article-title":"Propensity-Matched Comparisons of Clinical Outcomes After Transapical or Transfemoral Transcatheter Aortic Valve Replacement: A Placement of Aortic Transcatheter Valves (PARTNER)-I Trial Substudy","volume":"131","author":"Blackstone","year":"2015","journal-title":"Circulation"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1016\/j.jacc.2019.09.054","article-title":"Femoral Versus Nonfemoral Peripheral Access for Transcatheter Aortic Valve Replacement","volume":"74","author":"Beurtheret","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.jcin.2018.11.014","article-title":"Transcarotid Approach for Transcatheter Aortic Valve Replacement with the Sapien 3 Prosthesis","volume":"12","author":"Overtchouk","year":"2019","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.athoracsur.2017.07.017","article-title":"Subclavian\/Axillary Access for Self-Expanding Transcatheter Aortic Valve Re-placement Renders Equivalent Outcomes as Transfemoral","volume":"105","author":"Gleason","year":"2018","journal-title":"Ann. Thorac. Surg."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0195-668X(03)00201-X","article-title":"A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease","volume":"24","author":"Iung","year":"2003","journal-title":"Eur. Heart J."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1016\/j.jcin.2016.08.049","article-title":"Transcatheter Aortic Valve Replacement for the Treatment of Pure Native Aortic Valve Regurgitation","volume":"9","author":"Franzone","year":"2016","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2217\/fca-2021-0065","article-title":"The JenaValve pericardial transcatheter aortic valve replacement system to treat aortic valve disease","volume":"18","author":"Poschner","year":"2022","journal-title":"Future Cardiol."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"B41","DOI":"10.1016\/j.jacc.2020.09.106","article-title":"TCT CONNECT-92 Initial Single-Center Experience with Transfemoral Transcatheter Aortic Valve Replacement in Patients with Symptomatic Severe Aortic Regurgitation","volume":"76","author":"Gogia","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"e1553","DOI":"10.4244\/EIJ-D-18-00935","article-title":"First-in-human experience of a new-generation transfemoral transcatheter aortic valve for the treatment of severe aortic regurgitation: The J-Valve transfemoral system","volume":"14","author":"Hensey","year":"2019","journal-title":"EuroIntervention"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.4244\/EIJV9SSA17","article-title":"The Helio transcatheter aortic dock for patients with aortic regurgitation","volume":"9","author":"Barbanti","year":"2013","journal-title":"EuroIntervention"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/11\/3090\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:21:53Z","timestamp":1760138513000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/11\/3090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,30]]},"references-count":97,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2022,6]]}},"alternative-id":["jcm11113090"],"URL":"https:\/\/doi.org\/10.3390\/jcm11113090","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,30]]}}}