{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T05:54:44Z","timestamp":1763358884671,"version":"build-2065373602"},"reference-count":21,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>There are multiple reasons for which the \u201cupdates in assisted reproduction\u201d topic is and will be in the center of scientific attention\u2014both clinical and laboratory\u2014during the next decades. In this editorial, we present and discuss some of them.<\/jats:p>","DOI":"10.3390\/jcm11113129","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T09:24:29Z","timestamp":1653989069000},"page":"3129","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Updates in Assisted Reproduction"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0850-6623","authenticated-orcid":false,"given":"Charalampos","family":"Siristatidis","sequence":"first","affiliation":[{"name":"Assisted Reproduction Unit, Second Department of Obstetrics and Gynecology, \u201cAretaieion\u201d University Hospital, Medical School, National and Kapodistrian University of Athens, 76 Vas. Sofias Av., 11528 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kalliopi","family":"Syristatidi","sequence":"additional","affiliation":[{"name":"School of Medicine, University of St. Andrews, North Haugh, St. Andrews KY16 9TF, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8331-2402","authenticated-orcid":false,"given":"Michail","family":"Papapanou","sequence":"additional","affiliation":[{"name":"Assisted Reproduction Unit, Second Department of Obstetrics and Gynecology, \u201cAretaieion\u201d University Hospital, Medical School, National and Kapodistrian University of Athens, 76 Vas. Sofias Av., 11528 Athens, Greece"},{"name":"Obstetrics, Gynecology and Reproductive Medicine Working Group, Society of Junior Doctors, 15123 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Zikopoulos, A., Galani, A., Siristatidis, C., Georgiou, I., Mastora, E., Paraskevaidi, M., Zikopoulos, K., and Kolibianakis, E. (2022). Is Hysteroscopy Prior to IVF Associated with an Increased Probability of Live Births in Patients with Normal Transvaginal Scan Findings after Their First Failed IVF Trial?. J. Clin. Med., 11.","DOI":"10.3390\/jcm11051217"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Matsota, P., Sidiropoulou, T., Vrantza, T., Boutsikou, M., Midvighi, E., and Siristatidis, C. (2021). Comparison of Two Different Sedation Protocols during Transvaginal Oocyte Retrieval: Effects on Propofol Consumption and IVF Outcome: A Prospective Cohort Study. J. Clin. Med., 10.","DOI":"10.3390\/jcm10050963"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Rigos, I., Athanasiou, V., Vlahos, N., Papantoniou, N., Profer, D., and Siristatidis, C. (2021). The Addition of Endometrial Injury to Freeze-All Strategy in Women with Repeated Implantation Failures. J. Clin. Med., 10.","DOI":"10.3390\/jcm10102162"},{"key":"ref_4","unstructured":"The European IVF-Monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE), Wyns, C., De Geyter, C., Calhaz-Jorge, C., Kupka, M.S., Motrenko, T., Smeenk, J., Bergh, C., Tandler-Schneider, A., and Rugescu, I.A. (2021). ART in Europe, 2017: Results generated from European registries by ESHRE. Hum. Reprod. Open, 2021, hoab026."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Siristatidis, C. (2022, May 23). Special Issue \u201cUpdates in Assisted Reproduction Treatment\u201d. Available online: https:\/\/www.mdpi.com\/journal\/jcm\/special_issues\/updates_assisted_reproduction_treatment.","DOI":"10.3390\/jcm11113129"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"hoz017","DOI":"10.1093\/hropen\/hoz017","article-title":"Worldwide decline of IVF birth rates and its probable causes","volume":"2019","author":"Gleicher","year":"2019","journal-title":"Hum. Reprod. Open"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1056\/NEJMsb2101718","article-title":"The Imperative of Responsible Innovation in Reproductive Medicine","volume":"385","author":"Mastenbroek","year":"2021","journal-title":"N. Engl. J. Med."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Siristatidis, C., Karageorgiou, V., and Vogiatzi, P. (2021). Current Issues on Research Conducted to Improve Women\u2019s Health. Healthcare, 9.","DOI":"10.3390\/healthcare9010092"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"4615","DOI":"10.1038\/s41467-021-24793-3","article-title":"The evolution of our understanding of human development over the last 10 years","volume":"12","author":"Brivanlou","year":"2021","journal-title":"Nat. Commun."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Siristatidis, C., Dafopoulos, K., Papapanou, M., Stavros, S., Pouliakis, A., Eleftheriades, A., Sidiropoulou, T., and Vlahos, N. (2021). Why Has Metabolomics So Far Not Managed to Efficiently Contribute to the Improvement of Assisted Reproduction Outcomes? The Answer through a Review of the Best Available Current Evidence. Diagnostics, 11.","DOI":"10.3390\/diagnostics11091602"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Al-Inany, H.G., Youssef, M.A., Ayeleke, R.O., Brown, J., Lam, W.S., and Broekmans, F.J. (2016). 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Online"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1097\/AOG.0000000000000106","article-title":"Number of embryos transferred after in vitro fertilization and good perinatal outcome","volume":"123","author":"Kissin","year":"2014","journal-title":"Obstet. Gynecol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.fertnstert.2016.02.037","article-title":"Low versus atmospheric oxygen tension for embryo culture in assisted reproduction: A systematic review and meta-analysis","volume":"106","author":"Nastri","year":"2016","journal-title":"Fertil. Steril."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Youssef, M.M.A., Mantikou, E., van Wely, M., Van der Veen, F., Al-Inany, H.G., Repping, S., and Mastenbroek, S. (2015). Culture media for human pre-implantation embryos in assisted reproductive technology cycles. Cochrane Database Syst. Rev.","DOI":"10.1002\/14651858.CD007876.pub2"},{"key":"ref_17","unstructured":"Higgins, J., Thomas, J., Chandler, J., Cumpston, M., Li, T., Page, M., and Welch, V. (2022). Individual Participant Data. Cochrane Handbook for Systematic Reviews of Interventions, Wiley. [2nd ed.]. Version 6.3."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"c221","DOI":"10.1136\/bmj.c221","article-title":"Meta-analysis of individual participant data: Rationale, conduct, and reporting","volume":"340","author":"Riley","year":"2010","journal-title":"BMJ"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"3293","DOI":"10.1093\/humrep\/dei253","article-title":"Complications of IVF and ovulation induction","volume":"20","author":"Klemetti","year":"2005","journal-title":"Hum. Reprod."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1093\/humrep\/den068","article-title":"Revised guidelines for good practice in IVF laboratories","volume":"23","author":"Magli","year":"2008","journal-title":"Hum. Reprod."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"4614","DOI":"10.1038\/s41467-021-24794-2","article-title":"How will our understanding of human development evolve over the next 10 years","volume":"12","author":"Brivanlou","year":"2021","journal-title":"Nat. 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