{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:10:33Z","timestamp":1790745033848,"version":"4.1.0"},"reference-count":37,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T00:00:00Z","timestamp":1656028800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Introduction: Heart transplantation (HT) remains the gold-standard treatment but is conditioned by organ shortage. This study aimed to evaluate the value of Forrester classification and determine which congestion criteria had the best prognostic value to predict cardiorenal events on heart transplant waiting list. Methods and results: One hundred consecutive patients (54 years old, 72% men) with available right heart catheterization (RHC) listed in our center for HT between 2014 and 2019 were included. Cardiac catheterization measurements were obtained at the time of HT listing evaluation. Patients were classified according to perfusion and congestion status in four groups: \u201cwarm and dry\u201d, \u201cwarm and wet\u201d, \u201ccold and dry\u201d, and \u201ccold and wet\u201d. pWet was used to classify patients with pulmonary congestion and sWet for systemic congestion. The primary endpoint was the rate of a composite criteria of cardiogenic shock, acute kidney injury, and acute heart failure. Secondary endpoint was the incidence of waitlist death, emergency HT, or left ventricular assist device (LVAD) implantation at 12 months evaluated by Kaplan\u2013Meier curves and log-rank test. Only Forrester classification according to systemic congestion was associated with the primary composite endpoint (p = 0.011), while patients\u2019 profile according to pulmonary congestion was not (p = 0.331). Similarly, only the Forrester classification according to systemic congestion predicted waitlist death, emergency HT, or LVAD implantation at 12 months, with p = 0.010 and p = 0.189 for systemic and pulmonary congestion, respectively. Moreover, systemic congestion was the main driver of cardiorenal events on waitlist. Conclusions: Forrester classification according to systemic congestion is associated with cardiorenal outcomes in patients listed for heart transplant and the risk of waitlist death, emergency HT, or LVAD implantation at 12 months.<\/jats:p>","DOI":"10.3390\/jcm11133663","type":"journal-article","created":{"date-parts":[[2022,6,26]],"date-time":"2022-06-26T09:00:13Z","timestamp":1656234013000},"page":"3663","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prognosis of Advanced Heart Failure Patients according to Their Hemodynamic Profile Based on the Modified Forrester Classification"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9200-2729","authenticated-orcid":false,"given":"Guillaume","family":"Baudry","sequence":"first","affiliation":[{"name":"Service d\u2019insuffisance Cardiaque, H\u00f4pital Cardiovasculaire Louis Pradel, 69500 Bron, France"},{"name":"Centre d\u2019Investigations Cliniques Plurith\u00e9matique 1433, INSERM DCAC, CHRU de Nancy, F-CRIN INI-CRCT, Universit\u00e9 de Lorraine, 54500 Vandoeuvre-l\u00e8s-Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliette","family":"Bourdin","sequence":"additional","affiliation":[{"name":"Service d\u2019insuffisance Cardiaque, H\u00f4pital Cardiovasculaire Louis Pradel, 69500 Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raluca","family":"Mocan","sequence":"additional","affiliation":[{"name":"Service d\u2019insuffisance Cardiaque, H\u00f4pital Cardiovasculaire Louis Pradel, 69500 Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Hugon-Vallet","sequence":"additional","affiliation":[{"name":"Service d\u2019insuffisance Cardiaque, H\u00f4pital Cardiovasculaire Louis Pradel, 69500 Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Pozzi","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Cardiaque, H\u00f4pital Cardiovasculaire Louis Pradel, 69500 Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7849-1968","authenticated-orcid":false,"given":"Antoine","family":"Jobb\u00e9-Duval","sequence":"additional","affiliation":[{"name":"Service d\u2019insuffisance Cardiaque, H\u00f4pital Cardiovasculaire Louis Pradel, 69500 Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Paulo","sequence":"additional","affiliation":[{"name":"Service d\u2019insuffisance Cardiaque, H\u00f4pital Cardiovasculaire Louis Pradel, 69500 Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Rossignol","sequence":"additional","affiliation":[{"name":"Centre d\u2019Investigations Cliniques Plurith\u00e9matique 1433, INSERM DCAC, CHRU de Nancy, F-CRIN INI-CRCT, Universit\u00e9 de Lorraine, 54500 Vandoeuvre-l\u00e8s-Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Sebbag","sequence":"additional","affiliation":[{"name":"Service d\u2019insuffisance Cardiaque, H\u00f4pital Cardiovasculaire Louis Pradel, 69500 Bron, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Girerd","sequence":"additional","affiliation":[{"name":"Centre d\u2019Investigations Cliniques Plurith\u00e9matique 1433, INSERM DCAC, CHRU de Nancy, F-CRIN INI-CRCT, Universit\u00e9 de Lorraine, 54500 Vandoeuvre-l\u00e8s-Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur. 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