{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T19:08:23Z","timestamp":1770750503963,"version":"3.50.0"},"reference-count":30,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T00:00:00Z","timestamp":1656288000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>This observational study compared optic coherence tomography (OCT) and B-scan in the detection of optic disc drusen. In total, 86 eyes of 50 patients with optic disc drusen (ODD) (36 bilateral) with a mean age of 34.68 \u00b1 23.81 years, and 54 eyes of 27 patients with papilledema, with a mean age of 35.42 years \u00b1 17.47, were examined. Patients with ODD, diagnosed with ultrasound, underwent spectral-domain OCT evaluation. With US, 28 ODD cases were classified as large (4 buried and 24 superficial), 58 were classified as point-like (6 buried, 49 superficial and 3 mixed). Then, all patients underwent OCT. OCT was able to detect the presence of ODD and\/or peripapillary hyperreflective ovoid mass structure (PHOMS) in 69 eyes (p &lt; 0.001). In particular, 7 eyes (8.14%) showed the presence of ODD alone, 25 eyes (29.07%) showed only PHOMS and 37 eyes (43.02%) showed ODD and PHOMS. In 17 eyes (19.77%) no ODD or PHOMS were detected. In the papilledema group, no ODD were observed with both US and OCT. OCT showed the presence of drusen or similar lesions in only 80.23% of the cases highlighted by the US scan, so it does not allow for certain ODD diagnoses, especially in the case of buried ODD.<\/jats:p>","DOI":"10.3390\/jcm11133715","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T22:31:14Z","timestamp":1656369074000},"page":"3715","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Optic Nerve Drusen Evaluation: A Comparison between Ultrasound and OCT"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2366-6556","authenticated-orcid":false,"given":"Nicola","family":"Rosa","sequence":"first","affiliation":[{"name":"Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Via S. Allende 43, 84081 Baronissi, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4566-0064","authenticated-orcid":false,"given":"Maddalena","family":"De Bernardo","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Via S. Allende 43, 84081 Baronissi, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Abbinante","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Via S. Allende 43, 84081 Baronissi, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Vecchio","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Via S. Allende 43, 84081 Baronissi, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1031-6434","authenticated-orcid":false,"given":"Ferdinando","family":"Cione","sequence":"additional","affiliation":[{"name":"Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Via S. Allende 43, 84081 Baronissi, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9689-6005","authenticated-orcid":false,"given":"Luigi","family":"Capasso","sequence":"additional","affiliation":[{"name":"Corneal Transplant Unit, ASL Napoli 1, 80100 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.dld.2019.11.009","article-title":"Pediatric liver diseases and ocular changes: What hepatologists and ophthalmologists should know and share with each other","volume":"52","author":"Vitiello","year":"2020","journal-title":"Dig. 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