{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T14:27:29Z","timestamp":1784903249925,"version":"3.55.0"},"reference-count":47,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T00:00:00Z","timestamp":1656374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI16\/01075"],"award-info":[{"award-number":["PI16\/01075"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["UE-FEDER 2016 RD16\/0017\/0010"],"award-info":[{"award-number":["UE-FEDER 2016 RD16\/0017\/0010"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["RD21\/0009\/0001"],"award-info":[{"award-number":["RD21\/0009\/0001"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Instituto de Salud Carlos III\u2014European Regional Development Fund -Red de Trastornos Adictivos (RTA)","award":["PI16\/01075"],"award-info":[{"award-number":["PI16\/01075"]}]},{"name":"Instituto de Salud Carlos III\u2014European Regional Development Fund -Red de Trastornos Adictivos (RTA)","award":["UE-FEDER 2016 RD16\/0017\/0010"],"award-info":[{"award-number":["UE-FEDER 2016 RD16\/0017\/0010"]}]},{"name":"Instituto de Salud Carlos III\u2014European Regional Development Fund -Red de Trastornos Adictivos (RTA)","award":["RD21\/0009\/0001"],"award-info":[{"award-number":["RD21\/0009\/0001"]}]},{"name":"Instituto de Salud Carlos III, Redes de Investigaci\u00f3n Cooperativa Orientadas a Resultados en Salud (RICORS), Red de Investigaci\u00f3n en Atenci\u00f3n Primaria (RIAPAd)","award":["PI16\/01075"],"award-info":[{"award-number":["PI16\/01075"]}]},{"name":"Instituto de Salud Carlos III, Redes de Investigaci\u00f3n Cooperativa Orientadas a Resultados en Salud (RICORS), Red de Investigaci\u00f3n en Atenci\u00f3n Primaria (RIAPAd)","award":["UE-FEDER 2016 RD16\/0017\/0010"],"award-info":[{"award-number":["UE-FEDER 2016 RD16\/0017\/0010"]}]},{"name":"Instituto de Salud Carlos III, Redes de Investigaci\u00f3n Cooperativa Orientadas a Resultados en Salud (RICORS), Red de Investigaci\u00f3n en Atenci\u00f3n Primaria (RIAPAd)","award":["RD21\/0009\/0001"],"award-info":[{"award-number":["RD21\/0009\/0001"]}]},{"name":"European Union NextGenerationEU, Mecanismo para la Recuperaci\u00f3n y la Resiliencia (MRR)","award":["PI16\/01075"],"award-info":[{"award-number":["PI16\/01075"]}]},{"name":"European Union NextGenerationEU, Mecanismo para la Recuperaci\u00f3n y la Resiliencia (MRR)","award":["UE-FEDER 2016 RD16\/0017\/0010"],"award-info":[{"award-number":["UE-FEDER 2016 RD16\/0017\/0010"]}]},{"name":"European Union NextGenerationEU, Mecanismo para la Recuperaci\u00f3n y la Resiliencia (MRR)","award":["RD21\/0009\/0001"],"award-info":[{"award-number":["RD21\/0009\/0001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>The coexistence of a substance use disorder and another mental disorder in the same individual has been called dual disorder or dual diagnosis. This study aimed to examine the prevalence of lifetime dual disorder in individuals with alcohol or cocaine use disorder and their retention in treatment. We conducted a pilot cohort study of individuals (n = 1356) with alcohol or cocaine use disorder admitted to treatment in the public outpatient services of Barcelona (Spain) from January 2015 to August 2017 (followed-up until February 2018). Descriptive statistics, Kaplan\u2013Meier survival curves and a multivariable Cox regression model were estimated. The lifetime prevalence of screening positive for dual disorder was 74%. At 1 year of follow-up, &gt;75% of the cohort remained in treatment. On multivariable analysis, the factors associated with treatment dropout were a positive screening for lifetime dual disorder (HR = 1.26; 95% CI = 1.00\u20131.60), alcohol use (HR = 1.35; 95% CI = 1.04\u20131.77), polysubstance use (alcohol or cocaine and cannabis use) (HR = 1.60; 95% CI = 1.03\u20132.49) and living alone (HR = 1.34; 95% CI = 1.04\u20131.72). Lifetime dual disorder is a prevalent issue among individuals with alcohol or cocaine use disorders and could influence their dropout from treatment in public outpatient drug dependence care centres, along with alcohol use, polysubstance use and social conditions, such as living alone. We need a large-scale study with prolonged follow-up to confirm these preliminary results.<\/jats:p>","DOI":"10.3390\/jcm11133760","type":"journal-article","created":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T01:48:38Z","timestamp":1656467318000},"page":"3760","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Lifetime Dual Disorder Screening and Treatment Retention: A Pilot Cohort Study"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6233-491X","authenticated-orcid":false,"given":"Beatriz","family":"Pu\u00e9rtolas-Gracia","sequence":"first","affiliation":[{"name":"Ag\u00e8ncia de Salut P\u00fablica de Barcelona, 08023 Barcelona, Spain"},{"name":"Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), 08003 Barcelona, Spain"},{"name":"Department of Experimental and Health Sciences, Universitat Pompeu Fabra (UPF), 08002 Barcelona, Spain"},{"name":"CIBER Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6501-7079","authenticated-orcid":false,"given":"Mar\u00eda Gabriela","family":"Barbaglia","sequence":"additional","affiliation":[{"name":"Ag\u00e8ncia de Salut P\u00fablica de Barcelona, 08023 Barcelona, Spain"},{"name":"Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), 08003 Barcelona, Spain"},{"name":"Department of Experimental and Health Sciences, Universitat Pompeu Fabra (UPF), 08002 Barcelona, Spain"},{"name":"Biomedical Research Institute Sant Pau, IIB Sant Pau, Sant Antoni M\u00aa Claret 167, 08025 Barcelona, Spain"},{"name":"Red de Investigaci\u00f3n en Atenci\u00f3n Primaria en Adicciones (RIAPAd), 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merc\u00e8","family":"Gotsens","sequence":"additional","affiliation":[{"name":"Ag\u00e8ncia de Salut P\u00fablica de Barcelona, 08023 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2568-7550","authenticated-orcid":false,"given":"Oleguer","family":"Par\u00e9s-Badell","sequence":"additional","affiliation":[{"name":"Ag\u00e8ncia de Salut P\u00fablica de Barcelona, 08023 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Teresa","family":"Brugal","sequence":"additional","affiliation":[{"name":"Ag\u00e8ncia de Salut P\u00fablica de Barcelona, 08023 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6222-4761","authenticated-orcid":false,"given":"Marta","family":"Torrens","sequence":"additional","affiliation":[{"name":"Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), 08003 Barcelona, Spain"},{"name":"Red de Investigaci\u00f3n en Atenci\u00f3n Primaria en Adicciones (RIAPAd), 28029 Madrid, Spain"},{"name":"Faculty of Medicine, Universitat Aut\u00f2noma de Barcelona (UAB), 08193 Barcelona, Spain"},{"name":"Faculty of Medicine, Universitat de Vic i Catalunya Central, Vic, 08500 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara","family":"Trevi\u00f1o","sequence":"additional","affiliation":[{"name":"Ag\u00e8ncia de Salut P\u00fablica de Barcelona, 08023 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Concepci\u00f3n","family":"Rodr\u00edguez-D\u00edaz","sequence":"additional","affiliation":[{"name":"Ag\u00e8ncia de Salut P\u00fablica de Barcelona, 08023 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"V\u00e1zquez-V\u00e1zquez","sequence":"additional","affiliation":[{"name":"Ag\u00e8ncia de Salut P\u00fablica de Barcelona, 08023 Barcelona, 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