{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:38:24Z","timestamp":1790836704797,"version":"4.1.0"},"reference-count":71,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T00:00:00Z","timestamp":1656547200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Inappropriate prescribing in the elderly is a risk factor for higher adverse drugs reactions, hospitalisation, and mortality rates. Therefore, it is necessary to identify irrational prescriptions and implement interventions to improve geriatric clinical practices in nursing homes. This study aimed to examine and compare the prevalence of potentially inappropriate medications in nursing home residents using three different updated criteria: 2019 Beers criteria, PRISCUS list, and v2 STOPP criteria, and to determine the prevalence of potential prescribing omissions according to v2 START criteria. A descriptive, observational, and cross-sectional study design was used. A total of 218 residents were involved in this study. Data on drug use were collected from medical charts. Information was screened with the software CheckTheMeds. Potentially inappropriate medications were present in 96.3%, 90.8%, and 35.3% of residents, according to the STOPP, Beers, and PRISCUS criteria or list, respectively. Inappropriate medication was found to be significantly associated with polypharmacy and severe or moderate drug\u2013drug interactions with the three tools and with pathologies and unnecessary drugs only for STOPP criteria. The most frequent inappropriate medications were benzodiazepines and proton pump inhibitors. A regular use of software to review medications in nursing home residents would help to reduce the risk of these drug-related problems.<\/jats:p>","DOI":"10.3390\/jcm11133808","type":"journal-article","created":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:21:50Z","timestamp":1656634910000},"page":"3808","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Potentially Inappropriate Medication and Polypharmacy in Nursing Home Residents: A Cross-Sectional Study"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3729-5431","authenticated-orcid":false,"given":"Raquel","family":"D\u00edez","sequence":"first","affiliation":[{"name":"Pharmacology, Department of Biomedical Sciences, Faculty of Health Sciences, Institute of Biomedicine (IBIOMED), University of Le\u00f3n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Cadenas","sequence":"additional","affiliation":[{"name":"Pharmacology, Department of Biomedical Sciences, Faculty of Health Sciences, Institute of Biomedicine (IBIOMED), University of Le\u00f3n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julen","family":"Susperregui","sequence":"additional","affiliation":[{"name":"Applied Mathematics, Department of Mathematics, University of Le\u00f3n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3311-4226","authenticated-orcid":false,"given":"Ana M.","family":"Sahag\u00fan","sequence":"additional","affiliation":[{"name":"Pharmacology, Department of Biomedical Sciences, Faculty of Health Sciences, Institute of Biomedicine (IBIOMED), University of Le\u00f3n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00e9lida","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Pharmacology, Department of Biomedical Sciences, Faculty of Health Sciences, Institute of Biomedicine (IBIOMED), University of Le\u00f3n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7821-9502","authenticated-orcid":false,"given":"Juan J.","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Pharmacology, Department of Biomedical Sciences, Faculty of Health Sciences, Institute of Biomedicine (IBIOMED), University of Le\u00f3n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0208-9542","authenticated-orcid":false,"given":"Matilde","family":"Sierra","sequence":"additional","affiliation":[{"name":"Pharmacology, Department of Biomedical Sciences, Faculty of Health Sciences, Institute of Biomedicine (IBIOMED), University of Le\u00f3n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6229-9560","authenticated-orcid":false,"given":"Cristina","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"Pharmacology, Department of Biomedical Sciences, Faculty of Health Sciences, Institute of Biomedicine (IBIOMED), University of Le\u00f3n, 24071 Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,30]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2022, April 08). 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