{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:36:23Z","timestamp":1790793383848,"version":"4.1.0"},"reference-count":71,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T00:00:00Z","timestamp":1656979200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Tool Cage Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Interest in palliative care has increased in recent times, particularly in its multidisciplinary approach developed to meet the needs of patients with a life-threatening disease and their families. Although the modern concept of palliative simultaneous care postulates the adoption of these qualitative treatments early on during the life-threatening disease (and potentially just after the diagnosis), palliative care is still reserved for patients at the end of their life in most of the clinical realities, and thus is consequently mistaken for hospice care. Patients with acute or chronic kidney disease (CKD) usually experience poor quality of life and decreased survival expectancy and thus may benefit from palliative care. Palliative care requires close collaboration among multiple health care providers, patients, and their families to share the diagnosis, prognosis, realistic treatment goals, and treatment decisions. Several approaches, such as conservative management, extracorporeal, and peritoneal palliative dialysis, can be attempted to globally meet the needs of patients with kidney disease (e.g., physical, social, psychological, or spiritual needs). Particularly for frail patients, pharmacologic management or peritoneal dialysis may be more appropriate than extracorporeal treatment. Extracorporeal dialysis treatment may be disproportionate in these patients and associated with a high burden of symptoms correlated with this invasive procedure. For those patients undergoing extracorporeal dialysis, individualized goal setting and a broader concept of adequacy should be considered as the foundations of extracorporeal palliative dialysis. Interestingly, little evidence is available on palliative and end of life care for acute kidney injury (AKI) patients. In this review, the main variables influencing medical decision-making about palliative care in patients with kidney disease are described, as well as the different approaches that can fulfill the needs of patients with CKD and AKI.<\/jats:p>","DOI":"10.3390\/jcm11133923","type":"journal-article","created":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T10:21:33Z","timestamp":1657016493000},"page":"3923","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Palliative Care for Patients with Kidney Disease"],"prefix":"10.3390","volume":"11","author":[{"given":"Iacopo","family":"Lanini","sequence":"first","affiliation":[{"name":"Department of Health Sciences, Section of Anesthesia, Intensive Care and Pain Medicine, University of Florence, 50121 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0973-162X","authenticated-orcid":false,"given":"Sara","family":"Samoni","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Dialysis, ASST Lariana, S. Anna Hospital, 22042 Como, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faeq","family":"Husain-Syed","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Division of Nephrology, Pulmonology and Critical Care Medicine, University Hospital Giessen and Marburg, 35392 Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Fabbri","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Section of Anesthesia, Intensive Care and Pain Medicine, University of Florence, 50121 Florence, Italy"},{"name":"Department of Anesthesia and Intensive Care, Section of Oncological Anesthesia, and Intensive Care, Azienda Ospedaliero Universitaria Careggi, 50134 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Canzani","sequence":"additional","affiliation":[{"name":"Palliative Care, USL Toscana Centro, 50122 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Messeri","sequence":"additional","affiliation":[{"name":"Palliative Care, USL Toscana Centro, 50122 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rocco Domenico","family":"Mediati","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care, Section of Pain Therapy and Palliative Care, Azienda Ospedaliero Universitaria Careggi, 50134 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaccaria","family":"Ricci","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Section of Anesthesia, Intensive Care and Pain Medicine, University of Florence, 50121 Florence, Italy"},{"name":"Pediatric Intensive Care Unit, Meyer Children\u2019s University Hospital, 50139 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Romagnoli","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Section of Anesthesia, Intensive Care and Pain Medicine, University of Florence, 50121 Florence, Italy"},{"name":"Department of Anesthesia and Intensive Care, Section of Oncological Anesthesia, and Intensive Care, Azienda Ospedaliero Universitaria Careggi, 50134 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Villa","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Section of Anesthesia, Intensive Care and Pain Medicine, University of Florence, 50121 Florence, Italy"},{"name":"Department of Anesthesia and Intensive Care, Section of Oncological Anesthesia, and Intensive Care, Azienda Ospedaliero Universitaria Careggi, 50134 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.17140\/PMHCOJ-1-104","article-title":"Palliative care for nephropathic patients","volume":"1","author":"Villa","year":"2015","journal-title":"Palliat. 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