{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T15:37:39Z","timestamp":1772811459473,"version":"3.50.1"},"reference-count":30,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T00:00:00Z","timestamp":1657411200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Siberian Branch of the Russian Academy of Sciences within the Basic Research Topic of Research Institute for Complex Issues of Cardiovascular Diseases","award":["0419-2022-0002"],"award-info":[{"award-number":["0419-2022-0002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Objective. Right ventricular (RV) dysfunction after coronary artery bypass grafting (CABG) is associated with increased mortality and morbidity. In previous studies, the parameters of RV systolic function were mainly assessed, while the dynamics of RV diastolic function after surgery was practically not studied. The aim of this study was to study the dynamics of indicators of systolic and diastolic RV function after CABG as well as to identify factors associated with their presence. Methods. The study included 160 patients who underwent CABG and 36 volunteers with no history of coronary artery disease (CAD) as a control group. Echocardiographic examination of patients was performed to assess systolic and diastolic RV dysfunction before surgery and 18 months after CABG. A level of s\u2019t &lt; 10 cm\/sec or TAPSE &lt; 16 mm was considered as a sign of existing RV systolic dysfunction. RV diastolic dysfunction was defined as an Et\/At ratio &lt; 0.8 or &gt;2.1 and\/or an Et\/et\u2019 ratio &gt; 6. Results. In CAD patients 18 months after CABG, there was an increase in the frequency of the right ventricular systolic (from 7.5% to 30%, p &lt; 0.001) and diastolic (from 41.8% to 57.5%, p &lt; 0.001) dysfunction. An increase in TAPSE (p = 0.007), a decrease in e\u2019t (p = 0.005), and the presence of RV systolic dysfunction before surgery (p = 0.023) was associated with a significant increase in the likelihood of detecting RV systolic dysfunction 18 months after CABG (\u03c72(3) = 17.4, p = 0.001). High values of At before surgery (p = 0.021) and old myocardial infarction (p = 0.023) were significantly associated with an increased likelihood of detection of RV diastolic dysfunction 18 months after CABG (\u03c72(2) = 10.78, p = 0.005). Conclusions. This study demonstrated that in CAD patients 18 months after CABG, there was an increase in the frequency of right ventricular systolic and diastolic dysfunction. We also established the initial clinical, echocardiographic parameters, and perioperative complications associated with the presence of these changes in the postoperative period. The clinical and prognostic significance of the presence of systolic and\/or diastolic RV dysfunction in patients 18 months after CABG remains to be explored.<\/jats:p>","DOI":"10.3390\/jcm11143994","type":"journal-article","created":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T22:48:00Z","timestamp":1657493280000},"page":"3994","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Indicators of the Right Ventricle Systolic and Diastolic Function 18 Months after Coronary Bypass Surgery"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0963-4793","authenticated-orcid":false,"given":"Alexey N.","family":"Sumin","sequence":"first","affiliation":[{"name":"Laboratory of Comorbidity in Cardiovascular Diseases, Department of Clinical Cardiology, Federal State Budgetary Scientific Institution \u201cResearch Institute for Complex Issues of Cardiovascular Disease\u201d, Sosnoviy Blvd., 6, 650002 Kemerovo, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna V.","family":"Shcheglova","sequence":"additional","affiliation":[{"name":"Laboratory of Comorbidity in Cardiovascular Diseases, Department of Clinical Cardiology, Federal State Budgetary Scientific Institution \u201cResearch Institute for Complex Issues of Cardiovascular Disease\u201d, Sosnoviy Blvd., 6, 650002 Kemerovo, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekaterina V.","family":"Korok","sequence":"additional","affiliation":[{"name":"Laboratory of Comorbidity in Cardiovascular Diseases, Department of Clinical Cardiology, Federal State Budgetary Scientific Institution \u201cResearch Institute for Complex Issues of Cardiovascular Disease\u201d, Sosnoviy Blvd., 6, 650002 Kemerovo, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatjana Ju.","family":"Sergeeva","sequence":"additional","affiliation":[{"name":"Laboratory of Comorbidity in Cardiovascular Diseases, Department of Clinical Cardiology, Federal State Budgetary Scientific Institution \u201cResearch Institute for Complex Issues of Cardiovascular Disease\u201d, Sosnoviy Blvd., 6, 650002 Kemerovo, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/eurheartj\/ehy394","article-title":"2018 ESC\/EACTS Guidelines on myocardial revascularization","volume":"40","author":"Neumann","year":"2019","journal-title":"Eur. Heart J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1097\/EJA.0000000000000149","article-title":"Right ventricular systolic dysfunction and vena cava dilatation precede alteration of renal function in adult patients undergoing cardiac surgery: An observational study","volume":"32","author":"Guinot","year":"2015","journal-title":"Eur. J. Anaesthesiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.1016\/j.athoracsur.2015.11.035","article-title":"Right ventricular systolic dysfunction assessed by cardiac magnetic resonance is a strong predictor of cardiovascular death after coronary bypass grafting","volume":"101","author":"Pouleur","year":"2016","journal-title":"Ann. Thorac. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1530\/ERP-18-0041","article-title":"Pre-operative right ventricular echocardiographic parameters associated with short-term outcomes and long-term mortality after CABG","volume":"5","author":"Chowdhury","year":"2018","journal-title":"Echo Res. Pract."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Levy, D., Laghlam, D., Estagnasie, P., Brusset, A., Squara, P., and Nguyen, L.S. (2021). Post-operative Right Ventricular Failure After Cardiac Surgery: A Cohort Study. Front. Cardiovasc. Med., 8.","DOI":"10.3389\/fcvm.2021.667328"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1053\/j.semtcvs.2012.08.001","article-title":"Right ventricular failure after cardiac surgery: Management strategies","volume":"24","author":"Itagaki","year":"2012","journal-title":"Semin. Thorac. Cardiovasc. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1053\/j.jvca.2017.06.019","article-title":"Markers of Right Ventricular Dysfunction in Adult Cardiac Surgical Patients","volume":"31","author":"Zochios","year":"2017","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1080\/14017431.2016.1264621","article-title":"Right ventricular dysfunction after cardiac surgery\u2014Diagnostic options","volume":"51","author":"Ravn","year":"2017","journal-title":"Scand. Cardiovasc. J."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"e315","DOI":"10.1016\/j.jtcvs.2019.05.064","article-title":"Postoperative right ventricular dysfunction-Integrating right heart profiles beyond long-axis function","volume":"159","author":"Denault","year":"2020","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1016\/j.jtcvs.2014.09.117","article-title":"Surgical Treatment for Ischemic Heart Failure Investigators. Implication of right ventricular dysfunction on long-term outcome in patients with ischemic cardiomyopathy undergoing coronary artery bypass grafting with or without surgical ventricular reconstruction","volume":"149","author":"Kukulski","year":"2015","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Bootsma, I.T., Scheeren, T.W.L., de Lange, F., Haenen, J., Boonstra, P.W., and Boerma, E.C. (2018). Impaired right ventricular ejection fraction after cardiac surgery is associated with a complicated ICU stay. J. Intensive Care, 6.","DOI":"10.1186\/s40560-018-0351-3"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1053\/j.jvca.2019.01.036","article-title":"Can Echocardiographic Right Ventricular Function Parameters Predict Vasoactive Support Requirement After Tetralogy of Fallot Repair?","volume":"33","author":"Krishna","year":"2019","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1177\/2048872618768004","article-title":"Which echocardiographic parameters improve the risk prediction for peri-operative outcomes in patients undergoing coronary bypass surgery: A prospective study","volume":"9","author":"Magne","year":"2020","journal-title":"Eur. Heart J. Acute Cardiovasc. Care."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1086\/681268","article-title":"Abnormal right ventricular relaxation in pulmonary hypertension","volume":"5","author":"Murch","year":"2015","journal-title":"Pulm Circ."},{"key":"ref_15","first-page":"311","article-title":"Impaired right ventricular filling in patients with a chronic coronary syndrome","volume":"23","author":"Sumin","year":"2021","journal-title":"Med Ultrason."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1053\/j.jvca.2020.09.100","article-title":"Preexisting Right Ventricular Diastolic Dysfunction and Postoperative Cardiac Complications in Patients Undergoing Nonemergency Coronary Artery Bypass Surgery","volume":"35","author":"Sumin","year":"2021","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Zanobini, M., Loardi, C., Poggio, P., Tamborini, G., Veglia, F., Di Minno, A., Myasoedova, V., Mammana, L.F., Biondi, R., and Pepi, M. (2018). The impact of pericardial approach and myocardial protection onto postoperative right ventricle function reduction. J. Cardiothorac. Surg., 13.","DOI":"10.1186\/s13019-018-0726-5"},{"key":"ref_18","first-page":"99","article-title":"Right ventricular dysfunction and associated factors in patients after coronary artery bypass grafting","volume":"15","author":"Chinikar","year":"2019","journal-title":"ARYA Atheroscler."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/ehjci\/jev014","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: An update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"16","author":"Lang","year":"2015","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1111\/j.1540-8175.2009.01084.x","article-title":"Assessment of right ventricular diastolic function by tissue Doppler imaging in patients with acute right ventricular myocardial infarction","volume":"27","author":"Mukhaini","year":"2010","journal-title":"Echocardiography"},{"key":"ref_21","first-page":"250","article-title":"Decreased right ventricular function after coronary artery bypass grafting","volume":"35","author":"Roshanali","year":"2008","journal-title":"Tex. Heart Inst. J."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1053\/j.jvca.2021.01.026","article-title":"Perioperative Course of Three-Dimensional-Derived Right Ventricular Strain in Coronary Artery Bypass Surgery: A Prospective, Observational, Pilot Trial","volume":"35","author":"Labus","year":"2021","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1053\/j.jvca.2020.06.086","article-title":"Changes in Right Ventricular Function After Off-Pump Coronary Artery Bypass Grafting","volume":"35","author":"Borde","year":"2021","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"238","DOI":"10.5761\/atcs.oa.18-00046","article-title":"Is Systolic Right Ventricular Function Reduced after Thoracic Non-Cardiac Surgery? A Propensity Matched Echocardiographic Analysis","volume":"24","author":"Steffen","year":"2018","journal-title":"Ann. Thorac. Cardiovasc. Surg."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Bening, C., Sales, V.L., Alhussini, K., Radakovic, D., Benitez, R.C., Madrahimov, N., Keller, D., and Leyh, R. (2021). Clinically inapparent right heart dysfunction is associated with reduced myofilament force development in coronary artery disease. BMC Cardiovasc. Disord., 21.","DOI":"10.1186\/s12872-021-01926-6"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"51","DOI":"10.17802\/2306-1278-2019-8-4S-51-61","article-title":"Moderate right ventricular systolic dysfunction in patients with chronic coronary syndrome\u2014What determines it?","volume":"8","author":"Sumin","year":"2019","journal-title":"Complex Issues Cardiovasc. Dis."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Lella, L.K., Sales, V.L., Goldsmith, Y., Chan, J., Iskandir, M., Gulkarov, I., Tortolani, A., Brener, S.J., Sacchi, T.J., and Heitner, J.F. (2015). Reduced Right Ventricular Function Predicts Long-Term Cardiac Re-Hospitalization after Cardiac Surgery. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0132808"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1111\/echo.12652","article-title":"The evaluation of preoperative right ventricular diastolic dysfunction on coronary artery disease patients with left ventricular dysfunction","volume":"31","author":"Jin","year":"2014","journal-title":"Echocardiography"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s10741-019-09785-2","article-title":"Right ventricular function after cardiac surgery: The diagnostic and prognostic role of echocardiography","volume":"24","author":"Mandoli","year":"2019","journal-title":"Heart Fail. Rev."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s10554-018-1428-8","article-title":"Echocardiographic assessment of right ventricular function: Current clinical practice","volume":"35","author":"Schneider","year":"2019","journal-title":"Int. J. Cardiovasc. Imaging"}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/14\/3994\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:47:34Z","timestamp":1760140054000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/14\/3994"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,10]]},"references-count":30,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2022,7]]}},"alternative-id":["jcm11143994"],"URL":"https:\/\/doi.org\/10.3390\/jcm11143994","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,10]]}}}