{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T04:53:20Z","timestamp":1762059200275,"version":"build-2065373602"},"reference-count":28,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:00:00Z","timestamp":1657843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Sticky Platelet Syndrome (SPS) is a disorder characterized by platelet hyperaggregability, diagnosed by studying in vitro platelet aggregation with ADP and epinephrine. It is the second most common cause of thrombophilia in Mexican Mestizos and manifests as an autosomal dominant trait which, combined with other coagulopathies, contributes significantly to the morbidity and mortality of patients with primary thrombophilia. It is easily treatable with antiplatelet drugs; however, the methods for diagnosis are not readily available in all clinical laboratories and the disorder is often overlooked by most clinicians. Herein, we present the results of more than 20 years of Mexican experience with the study of SPS in a Mestizo population.<\/jats:p>","DOI":"10.3390\/jcm11144100","type":"journal-article","created":{"date-parts":[[2022,7,17]],"date-time":"2022-07-17T22:57:06Z","timestamp":1658098626000},"page":"4100","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Primary Thrombophilia XVII: A Narrative Review of Sticky Platelet Syndrome in M\u00e9xico"],"prefix":"10.3390","volume":"11","author":[{"given":"Claudia","family":"Minutti-Zanella","sequence":"first","affiliation":[{"name":"Laboratorios RUIZ-Escuela de Ciencias M\u00e9dicas, Universidad Popular Aut\u00f3noma del Estado de Puebla (UPAEP), Puebla 72530, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0313-7312","authenticated-orcid":false,"given":"Laura","family":"Villarreal-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Hospital Universitario de Nuevo Le\u00f3n, Monterrey 64460, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo J.","family":"Ruiz-Arg\u00fcelles","sequence":"additional","affiliation":[{"name":"Centro de Hematolog\u00eda y Medicina Interna, Cl\u00ednica RUIZ, Puebla 72530, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1177\/107602969500100111","article-title":"Ten Years\u2019 Experience with the \u201cSticky Platelet Syndrome\u201d","volume":"1","author":"Mammen","year":"1995","journal-title":"Clin. 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