{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T11:35:50Z","timestamp":1771932950014,"version":"3.50.1"},"reference-count":57,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T00:00:00Z","timestamp":1658102400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Hallym University Medical Center Research Fund"},{"name":"Hallym University Research Fund"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>This study aimed to evaluate the association between dry eye and inner ear diseases in a Korean population. Methods: Data from the Korean National Health and Nutrition Survey (KNHANES V, 2010\u20132012), a national cross-sectional health examination and survey, were collected by the Korea Centers for Disease Control and Prevention. The association between dry eye and inner ear disease was determined using the chi-square test and logistic regression analysis. The individuals were divided into two age groups (&lt;60 and \u226560 years). Results: In total, 17,542 individuals (n = 11,932 in the &lt;60 years group and n = 5610 in the \u226560 years group) were enrolled. After adjusting for confounding factors, the logistic regression model revealed that the associated factors were dizziness and loss of balance experience (OR, 1.315; 95% CI, 1.143\u20131.513), self-awareness of abnormal voice (OR, 1.372; 95% CI, 1.120\u20131.679), subjective hearing discomfort (OR, 1.278; CI, 1.084\u20131.506), and tinnitus (OR, 1.265; 95% CI, 1.101\u20131.453). The inversely associated factor for dry eye was bilateral hearing loss (OR, 0.497; 95% CI, 0.367\u20130.672). The hearing threshold was lower in the dry eye group than in the non-dry eye group (p &lt; 0.05). Conclusions: Tinnitus was associated with dry eye and bilateral hearing loss was inversely associated with dry eye. These results suggest that hypersensitivity of the senses and nerves, which is neuropathic hyperesthesia, is one of the main mechanisms of dry eye. Treatment of neuropathy may help in treating dry eye associated with dizziness or tinnitus.<\/jats:p>","DOI":"10.3390\/jcm11144171","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T11:32:23Z","timestamp":1658143943000},"page":"4171","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Association of Dry Eye Diseases and Auditory Sensitivity"],"prefix":"10.3390","volume":"11","author":[{"given":"Kyung Wook","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Hallym University Medical Center, Hallym University College of Medicine, Seoul 07442, Korea"},{"name":"Hallym BioEyeTech Research Center, Hallym University College of Medicine, Seoul 07442, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Sun","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hallym University Medical Center, Hallym University College of Medicine, Seoul 07442, Korea"},{"name":"Hallym BioEyeTech Research Center, Hallym University College of Medicine, Seoul 07442, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiwon","family":"Chang","sequence":"additional","affiliation":[{"name":"Hallym BioEyeTech Research Center, Hallym University College of Medicine, Seoul 07442, Korea"},{"name":"Department of Otorhinolaryngology, Hallym University Medical Center, Hallym University College of Medicine, Seoul 07442, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Joo","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hallym University Medical Center, Hallym University College of Medicine, Seoul 07442, Korea"},{"name":"Hallym BioEyeTech Research Center, Hallym University College of Medicine, Seoul 07442, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jtos.2017.05.003","article-title":"TFOS DEWS II Epidemiology Report","volume":"15","author":"Stapleton","year":"2017","journal-title":"Ocul. 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