{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:58:36Z","timestamp":1781657916363,"version":"3.54.5"},"reference-count":18,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T00:00:00Z","timestamp":1658793600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: The endoscopic modified Lothrop procedure (EMLP) is a common procedure performed in patients with frontal sinus pathology. While performing this procedure, large segments of bone are exposed, which may lead to the promotion of frontal sinus neo-ostium stenosis. Here we examine the peri-operative differences in time to achieve healing in patients where a mucosal flap is used to cover the exposed bone on one side of the neo-ostium. Design: A randomised pilot study with 12 patients undergoing EMLP surgery participated in this study. Methods: Patients were randomised to undergo a mucosal flap on either the left or right side of the neo-ostium. Prior to surgery, patients completed a SNOT-22 and smell identification test. Patients were reviewed until the neo-ostium had healed on both sides. Once healing had occurred, a post-operative SNOT-22 score and smell identification test were recorded. Results: Average time to healing for the frontal sinus neo-ostium was 4.7 vs. 4.2 (p = 0.3) on the flap vs. non-flap side, respectively. There was an average 24.4 point (range: \u221275 to +9) decrease in SNOT-22 scores post-surgery. The post-operative USPIT score demonstrated an average increase of 6.6 points (range \u221213 to +27). Conclusion: We did not detect significant differences in peri-operative time toward healing in neo-ostiums where a single flap is utilised. Further studies are needed to determine whether the usage of a single neo-ostium flap affords any benefit over no flap on either ostium. SNOT-22 and UPSIT scores improved post-surgery.<\/jats:p>","DOI":"10.3390\/jcm11154329","type":"journal-article","created":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T04:59:16Z","timestamp":1658897956000},"page":"4329","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Anterior Pedicled Nasal Flap in Frontal Sinus Drill-Out Patients: A Randomised Controlled Pilot Study"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6828-9531","authenticated-orcid":false,"given":"Mark","family":"Bastianelli","sequence":"first","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery, Flinders Medical Centre, Bedford Park 5042, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7910-1477","authenticated-orcid":false,"given":"Lucy","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery, Flinders Medical Centre, Bedford Park 5042, Australia"},{"name":"College of Medicine and Public Health, Flinders University, Bedford Park 5042, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paige","family":"Moore","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery, Flinders Medical Centre, Bedford Park 5042, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isma Zafar","family":"Iqbal","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery, Flinders Medical Centre, Bedford Park 5042, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7898-9689","authenticated-orcid":false,"given":"Charmaine M.","family":"Woods","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery, Flinders Medical Centre, Bedford Park 5042, Australia"},{"name":"College of Medicine and Public Health, Flinders University, Bedford Park 5042, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7201-815X","authenticated-orcid":false,"given":"Eng H.","family":"Ooi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery, Flinders Medical Centre, Bedford Park 5042, Australia"},{"name":"College of Medicine and Public Health, Flinders University, Bedford Park 5042, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1002\/alr.21708","article-title":"Draf III mucosal graft technique: Long-term results","volume":"6","author":"Illing","year":"2016","journal-title":"Int. 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Otolaryngol.-Head Neck Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1097\/MLG.0b013e31806865be","article-title":"Frontal ostium restenosis after the endoscopic modified lothrop procedure","volume":"117","author":"Tran","year":"2007","journal-title":"Laryngoscope"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/MOO.0000000000000023","article-title":"What is the evidence for the use of mucosal flaps in Draf III procedures","volume":"22","author":"Wei","year":"2014","journal-title":"Curr. Opin. Otolaryngol. Head Neck Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1002\/lary.24422","article-title":"Frontal sinus drillout (modified Lothrop procedure): Long-term results in 204 patients","volume":"124","author":"Ting","year":"2014","journal-title":"Laryngoscope"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/00005537-200302000-00015","article-title":"Salvage frontal sinus surgery: The endoscopic modified Lothrop procedure","volume":"113","author":"Wormald","year":"2003","journal-title":"Laryngoscope"},{"key":"ref_18","first-page":"CD011988","article-title":"Sinonasal debridement versus no debridement for the postoperative care of patients undergoing endoscopic sinus surgery","volume":"2018","author":"Tzelnick","year":"2018","journal-title":"Cochrane Database Syst. Rev."}],"container-title":["Journal of Clinical Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/15\/4329\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:56:43Z","timestamp":1760140603000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2077-0383\/11\/15\/4329"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,26]]},"references-count":18,"journal-issue":{"issue":"15","published-online":{"date-parts":[[2022,8]]}},"alternative-id":["jcm11154329"],"URL":"https:\/\/doi.org\/10.3390\/jcm11154329","relation":{},"ISSN":["2077-0383"],"issn-type":[{"value":"2077-0383","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,26]]}}}