{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T11:29:05Z","timestamp":1763810945811,"version":"build-2065373602"},"reference-count":52,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Gingival recession is a mucogingival defect defined as the apical shifting of the gingival margin in relation to the CEJ. The use of connective tissue autografts allows for the obtention of very satisfactory results but is associated with undoubted disadvantages. The aim of the present work is to carry out a systematic review of the literature using a meta-analysis to investigate the clinical efficacy of xenogeneic collagen matrix (XCM) in the treatment of gingival recessions. This revision was carried out strictly following the guidelines published in the Cochrane Handbook. Thus, a meta-analysis was performed to calculate relative risks and standardized mean differences for each of the variables considered. The results of the meta-analysis show that CAF + CTG was statistically better than CAF + XCM in almost all the variables analyzed: complete root coverage (RR 0.46), mean root coverage (SMD \u22120.89), recession reduction (SMD \u22120.98), clinical attachment level (SMD \u22120.63) and gingival thickness (SMD \u22121.68). Meanwhile, CAF + XCM was slightly better than CAF alone in regard to: mean root coverage (SMD 0.51), recession reduction (SMD 0.47) and gingival thickness (SMD 0.56). It is possible to conclude that CAF + CTG still remains the gold standard in radicular coverage.<\/jats:p>","DOI":"10.3390\/jcm11154486","type":"journal-article","created":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T21:01:24Z","timestamp":1659387684000},"page":"4486","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A New Matrix for Soft Tissue Management"],"prefix":"10.3390","volume":"11","author":[{"given":"Daniele","family":"De Santis","sequence":"first","affiliation":[{"name":"Head and Neck Department, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37124 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umberto","family":"Luciano","sequence":"additional","affiliation":[{"name":"Head and Neck Department, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37124 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Pancera","sequence":"additional","affiliation":[{"name":"Head and Neck Department, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37124 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Castegnaro","sequence":"additional","affiliation":[{"name":"Head and Neck Department, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37124 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Alberti","sequence":"additional","affiliation":[{"name":"Head and Neck Department, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37124 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2226-9476","authenticated-orcid":false,"given":"Federico","family":"Gelpi","sequence":"additional","affiliation":[{"name":"Head and Neck Department, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37124 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S204","DOI":"10.1002\/JPER.16-0671","article-title":"Mucogingival conditions in the natural dentition: Narrative review, case definitions, and diagnostic considerations","volume":"89","author":"Cortellini","year":"2018","journal-title":"J. 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