{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:50:28Z","timestamp":1787028628738,"version":"build-2736575974"},"reference-count":48,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T00:00:00Z","timestamp":1659571200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005632","name":"National Centre for Research and Development","doi-asserted-by":"publisher","award":["STRATEGMED3\/306306\/4\/NCBR\/2017"],"award-info":[{"award-number":["STRATEGMED3\/306306\/4\/NCBR\/2017"]}],"id":[{"id":"10.13039\/501100005632","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>This paper aimed to assess language development in infants and toddlers with tuberous sclerosis complex (TSC) and epilepsy, which increase the risk of autism spectrum disorder. We assessed language development in 61 patients with TSC at 8\u201336 months using a standardized Speech Development and Communication Inventory tool. The results showed differences in outcomes due to the duration of the seizures and the number of drugs (pFDR = 0.007 **\u2014pFDR = 0.037 *). Children with TSC with longer epilepsy duration and receiving more antiepileptic drugs have a greater risk of language development delay.<\/jats:p>","DOI":"10.3390\/jcm11154564","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T21:52:48Z","timestamp":1659649968000},"page":"4564","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Epilepsy and Language Development in 8\u201336-Month-Old Toddlers with Tuberous Sclerosis Complex"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8986-1792","authenticated-orcid":false,"given":"Ma\u0142gorzata","family":"Fory\u015b-Basiejko","sequence":"first","affiliation":[{"name":"Department of Child Clinical Psychology and Family, Faculty of Psychology, University of Warsaw, 00-183 Warszawa, Poland"},{"name":"Department of Neurology and Epileptology, The Children\u2019s Memorial Health Institute, 04-736 Warszawa, Poland"},{"name":"Department of Pediatric Neurology, Medical University of Warsaw, 02-091 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Kotulska","sequence":"additional","affiliation":[{"name":"Department of Neurology and Epileptology, The Children\u2019s Memorial Health Institute, 04-736 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7213-6554","authenticated-orcid":false,"given":"Agnieszka","family":"Maryniak","sequence":"additional","affiliation":[{"name":"Department of Child Clinical Psychology and Family, Faculty of Psychology, University of Warsaw, 00-183 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1779-0478","authenticated-orcid":false,"given":"Agata","family":"Si\u0142uszyk","sequence":"additional","affiliation":[{"name":"Department of Pediatric Neurology, Medical University of Warsaw, 02-091 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Szkop","sequence":"additional","affiliation":[{"name":"Department of Neurology and Epileptology, The Children\u2019s Memorial Health Institute, 04-736 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julita","family":"Borkowska","sequence":"additional","affiliation":[{"name":"Department of Neurology and Epileptology, The Children\u2019s Memorial Health Institute, 04-736 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Sugalska","sequence":"additional","affiliation":[{"name":"Department of Pediatric Neurology, Medical University of Warsaw, 02-091 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7628-8691","authenticated-orcid":false,"given":"Jagoda","family":"G\u0142owacka-Walas","sequence":"additional","affiliation":[{"name":"Institute of Computer Science, Warsaw University of Technology, 00-665 Warszawa, Poland"},{"name":"Transition Technologies Science, 01-030 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergiusz","family":"J\u00f3\u017awiak","sequence":"additional","affiliation":[{"name":"Department of Pediatric Neurology, Medical University of Warsaw, 02-091 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"16035","DOI":"10.1038\/nrdp.2016.35","article-title":"Tuberous sclerosis complex","volume":"2","author":"Henske","year":"2016","journal-title":"Nat. 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