{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:09:34Z","timestamp":1790420974850,"version":"4.1.0"},"reference-count":51,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T00:00:00Z","timestamp":1660608000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>In recent years, solid organ transplantations, such as kidney or lung grafts, have been performed worldwide with an improvement of quality of life under immunosuppressive therapy and an increase in life expectancy, allowing young women to consider childbearing. In the current study, we conduct a retrospective study in two French centers for kidney and lung transplantations to evaluate the rate and outcomes of pregnancies, contraception and gynecological monitoring for women under 40 years old who underwent solid organ transplantation. Among 210 women, progestin was the most widely used contraceptive method. Of the 210 women, 24 (11.4%) conceived 33 pregnancies of which 25 (75.8%) were planned with an immunosuppressant therapy switch. Of the 33 pregnancies, 7 miscarried (21.2%) and 21 (63.7%) resulted in a live birth with a high rate of pre-eclampsia (50%). No graft rejections were observed during pregnancies. Among the deliveries, 19 were premature (90.5%, mostly due to induced delivery) and the C-section rate was high (52.4%). No particular pathology was identified among newborns. We conclude that pregnancies following solid organ transplantation are feasible, and while they are at an increased risk of pre-eclampsia and prematurity, they should still be permitted with close surveillance by a multidisciplinary care team.<\/jats:p>","DOI":"10.3390\/jcm11164792","type":"journal-article","created":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T23:44:25Z","timestamp":1660693465000},"page":"4792","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Pregnancies and Gynecological Follow-Up after Solid Organ Transplantation: Experience of a Decade"],"prefix":"10.3390","volume":"11","author":[{"given":"Alice","family":"Bedin","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9935-1203","authenticated-orcid":false,"given":"Marie","family":"Carbonnel","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France"},{"name":"Medical School, University of Versailles, Saint-Quentin-en-Yvelines, 55, Avenue de Paris, 78000 Versailles, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Snanoudj","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hospital Bic\u00eatre, 94220 Le Kremlin Bic\u00eatre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Roux","sequence":"additional","affiliation":[{"name":"Medical School, University of Versailles, Saint-Quentin-en-Yvelines, 55, Avenue de Paris, 78000 Versailles, France"},{"name":"Department of Pneumology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Vanlieferinghen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Marchiori","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2903-3303","authenticated-orcid":false,"given":"Alexandre","family":"Hertig","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Racowsky","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France"},{"name":"Medical School, University of Versailles, Saint-Quentin-en-Yvelines, 55, Avenue de Paris, 78000 Versailles, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Marc","family":"Ayoubi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France"},{"name":"Medical School, University of Versailles, Saint-Quentin-en-Yvelines, 55, Avenue de Paris, 78000 Versailles, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1111\/ajt.14702","article-title":"An economic assessment of contemporary kidney transplant practice","volume":"18","author":"Axelrod","year":"2018","journal-title":"Am. 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