{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:22:49Z","timestamp":1771467769085,"version":"3.50.1"},"reference-count":40,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T00:00:00Z","timestamp":1661299200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 110-2629-B-037-001-MY3"],"award-info":[{"award-number":["MOST 110-2629-B-037-001-MY3"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["KMUHS-11012"],"award-info":[{"award-number":["KMUHS-11012"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["KMUH107-7R40"],"award-info":[{"award-number":["KMUH107-7R40"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004694","name":"Kaohsiung Medical University","doi-asserted-by":"publisher","award":["MOST 110-2629-B-037-001-MY3"],"award-info":[{"award-number":["MOST 110-2629-B-037-001-MY3"]}],"id":[{"id":"10.13039\/501100004694","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004694","name":"Kaohsiung Medical University","doi-asserted-by":"publisher","award":["KMUHS-11012"],"award-info":[{"award-number":["KMUHS-11012"]}],"id":[{"id":"10.13039\/501100004694","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004694","name":"Kaohsiung Medical University","doi-asserted-by":"publisher","award":["KMUH107-7R40"],"award-info":[{"award-number":["KMUH107-7R40"]}],"id":[{"id":"10.13039\/501100004694","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","doi-asserted-by":"publisher","award":["MOST 110-2629-B-037-001-MY3"],"award-info":[{"award-number":["MOST 110-2629-B-037-001-MY3"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","doi-asserted-by":"publisher","award":["KMUHS-11012"],"award-info":[{"award-number":["KMUHS-11012"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","doi-asserted-by":"publisher","award":["KMUH107-7R40"],"award-info":[{"award-number":["KMUH107-7R40"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Our study aims to assess Pixel CO2 laser efficacy for female stress urinary incontinence (SUI). Methods: In the study, 25 women with SUI were included and scheduled for vaginal Pixel CO2 Laser (FemiLift\u2122, Alma Lasers, Israel) treatment. All subjects had a baseline and 6-month post-treatment assessment that included three-dimensional perineal ultrasound and validated questionnaires. Results: Data showed that monthly three-session vaginal Pixel CO2 Laser treatment significantly improved SUI symptoms, as evidenced by validated questionnaires, including UDI-6, IIQ-7, ICIQ, and vaginal laxity questionnaire (p &lt; 0.05). The Pixel CO2 Laser efficacy in vaginal treatment was 20\/25 (80%), and the perineal sonography showed that laser treatment significantly decreased bladder neck mobility and middle urethral area (during resting and straining). Permanent adverse events were not found. Conclusions: The results of our study suggested that for the treatment of mild to moderate SUI symptoms, Pixel CO2 Laser is effective and safe; however, more studies and a longer follow-up should be conducted to confirm its efficacy and durability.<\/jats:p>","DOI":"10.3390\/jcm11174971","type":"journal-article","created":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T23:48:58Z","timestamp":1661384938000},"page":"4971","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The Clinical Effects of Pixel CO2 Laser on Bladder Neck and Stress Urinary Incontinence"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1102-0512","authenticated-orcid":false,"given":"Cheng-Yu","family":"Long","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kaohsiung Medical Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan"},{"name":"Department of Obstetrics and Gynecology, Kaohsiung Municipal Siao-Gang Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan"},{"name":"Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 80708, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer Po-Ning","family":"Lee","sequence":"additional","affiliation":[{"name":"Vaginal Rejuvenation & Regenerative Center, Vigor Aesthetic Medical Group, Kaohsiung 81358, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi-Xi","family":"Loo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung 80145, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0873-4012","authenticated-orcid":false,"given":"Yi-Yin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kaohsiung Municipal Siao-Gang Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Lin","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kaohsiung Medical Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Wei","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kaohsiung Medical Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun-Ling","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kaohsiung Medical Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan"},{"name":"Department of Obstetrics and Gynecology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung 80145, Taiwan"},{"name":"Department of Obstetrics and Gynecology, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1007\/s11934-011-0206-0","article-title":"Epidemiology of stress urinary incontinence in women","volume":"12","author":"Reynolds","year":"2011","journal-title":"Curr. 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