{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T17:26:44Z","timestamp":1785432404724,"version":"3.56.0"},"reference-count":70,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2022,8,27]],"date-time":"2022-08-27T00:00:00Z","timestamp":1661558400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Erasmus+ Sport Programme (2017\u20132019) Enriched Sport Activity Program (ESA Program)","award":["2016-3723\/001-001"],"award-info":[{"award-number":["2016-3723\/001-001"]}]},{"name":"Erasmus+ Sport Programme (2017\u20132019) Enriched Sport Activity Program (ESA Program)","award":["579661-EPP-1-2016-2-IT-SPO-SCP"],"award-info":[{"award-number":["579661-EPP-1-2016-2-IT-SPO-SCP"]}]},{"name":"Round 2 Erasmus+ Sport Project","award":["2016-3723\/001-001"],"award-info":[{"award-number":["2016-3723\/001-001"]}]},{"name":"Round 2 Erasmus+ Sport Project","award":["579661-EPP-1-2016-2-IT-SPO-SCP"],"award-info":[{"award-number":["579661-EPP-1-2016-2-IT-SPO-SCP"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Many research studies have investigated motor impairments and delayed development in children with Down Syndrome (DS). However, very few studies detected these features in adults with DS. Hence, this study aimed to investigate the relationship between motor coordination and global development in subjects with DS, including adults. Furthermore, the second aim was to detect any differences in motor coordination and global development as a function of the practice of physical activity (PA) in this population. Methods: Twenty-five participants with DS (10 f, 15 m), with a chronological mean age of 27.24 years and development mean age of cognitive area of 4.93 years, were enrolled and divided into a physically active group (PA-G; n = 15) and a physically inactive group (PI-G; n = 10). All participants performed the Movement Assessment Battery for Children (M-ABC) to assess fine and gross motor skills, while the Developmental Profile 3 (DP-3) checklist was administered to the parents in order to screen strengths and weaknesses of five developmental areas of their relatives with DS. Results: Our results showed positive correlations between the following variables: global motor coordination and global development, global motor coordination and adaptive behavior development area, aiming and catching skills and global development, aiming and catching skills and adaptive behavior development area. As for the practice of PA, PA-G showed higher scores than PI-G in all the tasks of both the M-ABC and the DP-3, though significant differences were found only for the global motor coordination, for the aiming and catching skills, as well as for the physical development area. Conclusions: The findings of this study reinforce the need to implement and encourage the practice of PA in order to promote well-being and social inclusion in subjects with DS.<\/jats:p>","DOI":"10.3390\/jcm11175031","type":"journal-article","created":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T03:34:56Z","timestamp":1661744096000},"page":"5031","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Motor Coordination and Global Development in Subjects with Down Syndrome: The Influence of Physical Activity"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7372-3205","authenticated-orcid":false,"given":"Marianna","family":"Alesi","sequence":"first","affiliation":[{"name":"Department of Psychology, Educational Science and Human Movement, University of Palermo, 90128 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4575-8021","authenticated-orcid":false,"given":"Valerio","family":"Giustino","sequence":"additional","affiliation":[{"name":"Sport and Exercise Sciences Research Unit, Department of Psychology, Educational Science and Human Movement, University of Palermo, 90144 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5301-7023","authenticated-orcid":false,"given":"Ambra","family":"Gentile","sequence":"additional","affiliation":[{"name":"Department of Psychology, Educational Science and Human Movement, University of Palermo, 90128 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4595-3994","authenticated-orcid":false,"given":"Manuel","family":"G\u00f3mez-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Physical Activity and Sport, Faculty of Sports Sciences, University of Murcia, Santiago de la Ribera, 30720 Murcia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7758-7175","authenticated-orcid":false,"given":"Giuseppe","family":"Battaglia","sequence":"additional","affiliation":[{"name":"Sport and Exercise Sciences Research Unit, Department of Psychology, Educational Science and Human Movement, University of Palermo, 90144 Palermo, Italy"},{"name":"Regional Sports School of CONI Sicilia, 90141 Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.5535\/arm.2017.41.1.97","article-title":"Motor and Cognitive Developmental Profiles in Children With Down Syndrome","volume":"41","author":"Kim","year":"2017","journal-title":"Ann. 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