{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:15:19Z","timestamp":1792167319172,"version":"4.4.0"},"reference-count":42,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T00:00:00Z","timestamp":1662422400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Data collection regarding the effects of COVID-19 on reproduction is ongoing. This study examined the effect of COVID-19 on IVF cycle parameters and early pregnancy outcomes. It included two arms: the first compared non-exposed cycles to post-SARS-CoV-2 IVF cycles. Sperm parameters were also compared. The second, prospective arm compared pregnancy outcomes among IVF patients who contracted COVID-19 during early pregnancy to those who did not. None of the patients were vaccinated against SARS-CoV-2. The first arm included 60 treatment cycles of women with confirmed COVID-19, compared to 60 non-exposed cycles (either the same patient before exposure or matched non-exposed patients). The outcomes of the treatment cycles did not differ significantly between exposed and non-exposed groups, including number of oocytes, endometrial thickness, fertilization rate and number of top-quality embryos. In 11 cycles, the male partner had also recently recovered: sperm concentration was lower post-exposure: 6.27 million\/mL vs. 16.5 pre-exposure (p = 0.008). In 189 patients with IVF-achieved pregnancies, pregnancy loss and hospital admissions did not differ between exposed and non-exposed groups. IVF treatment outcomes and the rate of early pregnancy loss appears to be unaffected by SARS-CoV-2 disease, despite a minor decline in sperm concentration among recent recoverees.<\/jats:p>","DOI":"10.3390\/jcm11185265","type":"journal-article","created":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T20:52:51Z","timestamp":1662497571000},"page":"5265","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Mild COVID-19 Was Not Associated with Impaired IVF Outcomes or Early Pregnancy Loss in IVF Patients"],"prefix":"10.3390","volume":"11","author":[{"given":"Yossef","family":"Kabalkin","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112102, 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Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arbel","family":"Moav-Zafrir","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112102, Israel"},{"name":"Division of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel"},{"name":"The IVF Unit, Hadassah Mount Scopus-Hebrew University Medical Center, Jerusalem 91240, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dua\u2019","family":"Khwies","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112102, Israel"},{"name":"Division of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel"},{"name":"The IVF Unit, Hadassah Mount Scopus-Hebrew University Medical Center, Jerusalem 91240, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assaf","family":"Ben-Meir","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112102, Israel"},{"name":"Division of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel"},{"name":"The IVF Unit, Hadassah Ein Kerem-Hebrew University Medical Center, Jerusalem 91220, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efrat","family":"Esh Broder","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112102, Israel"},{"name":"Division of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem 9112102, Israel"},{"name":"The IVF Unit, Hadassah Mount Scopus-Hebrew University Medical Center, Jerusalem 91240, 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