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Adaptive posture-balance cardiac rehabilitation exercise (APBCRE) is an emerging, balance-based therapy from clinical experience, but lacks evidence of validity. Our study aimed to observe and assess the rehabilitation effect of APBCRE on patients with cardiovascular diseases (CVDs). All participants received one-month APBCRE therapy evenly three times per week and two assessments before and after APBCRE. Each assessment included cardiopulmonary exercise testing (CPET), resting metabolic rate (RMR) detection, and three questionnaires about general health. The differences between two assessments were analyzed to evaluate the therapeutic effects of APBCRE. A total of 93 participants (80.65% male, 53.03 \u00b1 12.02 years) were included in the analysis. After one-month APBCRE, oxygen uptake (VO2, 11.16 \u00b1 2.91 to 12.85 \u00b1 3.17 mL\/min\/kg, p &lt; 0.01) at anaerobic threshold (AT), ventilation (VE, 28.87 \u00b1 7.26 to 32.42 \u00b1 8.50 mL\/min\/kg, p &lt; 0.01) at AT, respiratory exchange ratio (RER, 0.93 \u00b1 0.06 to 0.95 \u00b1 0.05, p &lt; 0.01) at AT and oxygen uptake efficiency slope (OUES, 1426.75 \u00b1 346.30 to 1547.19 \u00b1 403.49, p &lt; 0.01) significantly improved in CVD patients. The \u226455-year group had more positive improvements (VO2 at AT, 23% vs. 16%; OUES, 13% vs. 6%) compared with the &gt;55-year group. Quality of life was also increased after APBCRE (47.78 \u00b1 16.74 to 59.27 \u00b1 17.77, p &lt; 0.001). This study proved that APBCRE was a potentially available exercise rehabilitation modality for patients with CVDs, which performed significant increases in physical tolerance and quality of life, especially for \u226455-year patients.<\/jats:p>","DOI":"10.3390\/jcm11185345","type":"journal-article","created":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T01:44:03Z","timestamp":1663033443000},"page":"5345","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Adaptive Posture-Balance Cardiac Rehabilitation Exercise Significantly Improved Physical Tolerance in Patients with Cardiovascular Diseases"],"prefix":"10.3390","volume":"11","author":[{"given":"Mei","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital, Tianjin 300192, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bowen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxin","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Key Laboratory of Pulmonary Vascular Medicine, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Ji","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deyu","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital, Tianjin 300192, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaodong","family":"Pu","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital, Tianjin 300192, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingxiang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital, Tianjin 300192, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Tianjin Chest Hospital, Tianjin 300192, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinz","family":"Lowis","sequence":"additional","affiliation":[{"name":"Drei-Burgen-Klinik of German Pension Insurance of Rhineland-Palatinate, 55583 Bad Kreuznach, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1093\/eurheartj\/eht296","article-title":"2013 ESC Guidelines on the Management of Stable Coronary Artery Disease: The Task Force on the Management of Stable Coronary Artery Disease of the European Society of Cardiology","volume":"34","author":"Montalescot","year":"2013","journal-title":"Eur. 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