{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:43:01Z","timestamp":1790692981280,"version":"4.1.0"},"reference-count":64,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T00:00:00Z","timestamp":1663718400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"abstract":"<jats:p>Background: Chronic non-specific neck pain (CINP) is common, but the etiology remains unclear. This study aimed to examine the relationship between cervical muscle composition (cervical multifidus and longus capitis\/longus colli), morphometry, range of movement, muscle function, and disability severity (Neck Disability Index) in patients with CINP. Methods: From September 2020 to July 2021, subjects underwent cervical MRI and clinical tests (cervical range of motion, cranio-cervical flexion test, neck flexor, and extensor muscle endurance). MRI analysis comprised muscle cross-sectional area, volume, and fat infiltration of multifidus and longus colli between C4 and C7 levels. Results: Twenty-five participants were included. Multiple linear regression analysis indicated that NDI was positively correlated with the volume percentage of fat infiltration of the multifidus (B = 0.496), negatively correlated with fat-free muscle volume of the multifidus normalized by subject height (B = \u22120.230), and accounted for 32% of the variance. There was no relationship between neck disability and longus capitis\/longus colli morphology. We also found no relationship between neck disability scores, neck flexor or extensor muscle endurance, or the outcome motor control test of craniocervical flexion (p &gt; 0.05). Conclusions: Neck disability was moderately correlated with the percentage of fat volume in the multifidus muscle and fat-free volume of the multifidus. There was no relationship between NDI scores and muscle function test outcomes or any fat or volume measures pertaining to the longus colli muscle.<\/jats:p>","DOI":"10.3390\/jcm11195522","type":"journal-article","created":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T01:47:06Z","timestamp":1663811226000},"page":"5522","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Fat Infiltration of Multifidus Muscle Is Correlated with Neck Disability in Patients with Non-Specific Chronic Neck Pain"],"prefix":"10.3390","volume":"11","author":[{"given":"Francis","family":"Grondin","sequence":"first","affiliation":[{"name":"Laboratory IRISSE, EA4075, Faculty of Human and Environment Sciences, University of La R\u00e9union, 97430 Le Tampon, France"},{"name":"Neurosurgey Department, University Hospital of La R\u00e9union, 97410 Saint-Pierre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7246-1920","authenticated-orcid":false,"given":"S\u00e9bastien","family":"Freppel","sequence":"additional","affiliation":[{"name":"Neurosurgey Department, University Hospital of La R\u00e9union, 97410 Saint-Pierre, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwendolen","family":"Jull","sequence":"additional","affiliation":[{"name":"Physiotherapy, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane 4072, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"G\u00e9rard","sequence":"additional","affiliation":[{"name":"Institute of Health Engineering, University of Picardie Jules Verne, 80000 Amiens, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1033-8262","authenticated-orcid":false,"given":"Teddy","family":"Caderby","sequence":"additional","affiliation":[{"name":"Laboratory IRISSE, EA4075, Faculty of Human and Environment Sciences, University of La R\u00e9union, 97430 Le Tampon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2149-7939","authenticated-orcid":false,"given":"Nicolas","family":"Peyrot","sequence":"additional","affiliation":[{"name":"Laboratory IRISSE, EA4075, Faculty of Human and Environment Sciences, University of La R\u00e9union, 97430 Le Tampon, France"},{"name":"Laboratory Movement Interactions Performance, MIP UR4334, Le Mans University, 72000 Le Mans, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"m791","DOI":"10.1136\/bmj.m791","article-title":"Global, Regional, and National Burden of Neck Pain in the General Population, 1990\u20132017: Systematic Analysis of the Global Burden of Disease Study 2017","volume":"368","author":"Safiri","year":"2020","journal-title":"BMJ"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/S0140-6736(20)30925-9","article-title":"Global Burden of 369 Diseases and Injuries in 204 Countries and Territories, 1990\u20132019: A Systematic Analysis for the Global Burden of Disease Study 2019","volume":"396","author":"Vos","year":"2020","journal-title":"Lancet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.berh.2011.01.019","article-title":"The Epidemiology of Neck Pain","volume":"24","author":"Hoy","year":"2010","journal-title":"Best Pract. 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